Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J A, Gossen"'
Autor:
J. A. Gossen, D. Blecher, A. Van Duyn-Goedhart, P.P.W. van Buul, Hans-Jörg Martus, M. Novak, Willi Suter
Publikováno v:
Environmental and Molecular Mutagenesis. 34:216-220
In order to evaluate the pUR288-plasmid transgenic mouse model, utilizing the bacterial lacZ gene as the mutational target, radiation-induced mutagenesis was primarily analyzed in spermatogonial stem cells. A combined hydroxyurea (HU)–X-ray treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5355f77fba9e20c8d8b9e908eef32481
https://doi.org/10.1002/(sici)1098-2280(1999)34:2/3<216::aid-em22>3.0.co
https://doi.org/10.1002/(sici)1098-2280(1999)34:2/3<216::aid-em22>3.0.co
Autor:
Ekkehart W. Vogel, Firouz Darroudi, A.A. van Zeeland, J. A. Gossen, Leon H.F. Mullenders, Adayapalam T. Natarajan, Bruno Morolli, Paul H.M. Lohman, Harry Vrieling, J. Venema
Publikováno v:
Environmental Health Perspectives
The origin of cancer in the humans is considered to be a complex and multistep process. In all cases, however, the cancer cell contains a genome in which gene(s) are either altered or wrongly expressed. Therefore, alterations in DNA have been thought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1052733193e14bafc00dcc028b213b5d
https://doi.org/10.1289/ehp.9298155
https://doi.org/10.1289/ehp.9298155
Autor:
J. Vijg, Wim Huppes, J. A. Gossen, Christine D. Dijkstra, C. de Groot, J. G. J. Bauman, V. Smit, R. H. Ostendorf
Publikováno v:
Journal of Neurocytology. 21:129-136
Galactocerebrosidase-deficient oligodendrocytes of 'twitcher' (twi/twi) mice degenerate prematurely. Transplantation of normal bone marrow cells has been shown to alleviate symptoms and to prolong survival time. However, characteristic ataxia ('twitc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66faeb58ef4c2809b46cc5573f73c07
https://doi.org/10.1007/bf01189011
https://doi.org/10.1007/bf01189011
Autor:
H J, Martus, M, Novak, D, Blecher, A, van Duyn-Goedhart, W, Suter, J A, Gossen, P P, van Buul
Publikováno v:
Environmental and molecular mutagenesis. 34(2-3)
In order to evaluate the pUR288-plasmid transgenic mouse model, utilizing the bacterial lacZ gene as the mutational target, radiation-induced mutagenesis was primarily analyzed in spermatogonial stem cells. A combined hydroxyurea (HU)-X-ray treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b048a6b9a99f2771293c22f5ba3ba8e
https://pubmed.ncbi.nlm.nih.gov/10529747
https://pubmed.ncbi.nlm.nih.gov/10529747
Publikováno v:
Environmental and molecular mutagenesis. 28(4)
In order to help establish criteria for optimizing protocols for in vivo mutation studies, lacZ transgenic mice (Muta mouse) were treated with five consecutive daily doses of ethylnitrosourea (50 mg/kg), sampled at times up to 55 days after treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3224328d9ce267236c6f65e9244f2b9a
https://pubmed.ncbi.nlm.nih.gov/8991059
https://pubmed.ncbi.nlm.nih.gov/8991059
Publikováno v:
BioTechniques. 14(4)
A method for the efficient rescue of lac operator containing plasmids from transgenic mouse genomic DNA is described. The method is based on the high affinity of the LacI repressor protein for the lac operator sequence. Using the LacI repressor prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2dadb9cd6353433ad10bbbeab8bc0a6d
https://pubmed.ncbi.nlm.nih.gov/8476606
https://pubmed.ncbi.nlm.nih.gov/8476606
Autor:
J A, Gossen, J, Vijg
Publikováno v:
BioTechniques. 14(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::acbf27a8be9396897632775e4a1510a0
https://pubmed.ncbi.nlm.nih.gov/8457332
https://pubmed.ncbi.nlm.nih.gov/8457332
Autor:
Z. Farooqi, J. A. Gossen, Adayapalam T. Natarajan, Firouz Darroudi, Leon H.F. Mullenders, J. J. W. A. Boei, A.S. Balajee
Publikováno v:
Chromosome Segregation and Aneuploidy ISBN: 9783642849404
Three different assays were developed and standardised to study the aneugenic potential of known or suspected aneugens in vivo. (1) The cytokinesis blocked micronuclei (MN) assay and fluorescent in-situ hybridisation technique using mouse centromeric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aa0d5547db17e82e0d699fded18e2f1
https://doi.org/10.1007/978-3-642-84938-1_29
https://doi.org/10.1007/978-3-642-84938-1_29
Publikováno v:
Mutation research. 250(1-2)
To study spontaneous and induced mutagenesis in vivo we recently constructed a series of transgenic mice harboring different numbers of bacteriophage lambda shuttle vectors, provided with a LacZ mutational target gene, integrated in their genome. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e61beb9d6e26af9f3425c3b383ecb6
https://pubmed.ncbi.nlm.nih.gov/1944355
https://pubmed.ncbi.nlm.nih.gov/1944355
Publikováno v:
Progress in clinical and biological research. 372
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02c11eb135160e82342f1558c2694516
https://pubmed.ncbi.nlm.nih.gov/1835538
https://pubmed.ncbi.nlm.nih.gov/1835538