Zobrazeno 1 - 10 of 21 pro vyhledávání: '"J A, Glasel"'
1
Analysis of the binding site architecture of monoclonal antibodies to morphine by using competitive ligand binding and molecular modeling
Autor: P H Kussie, J M Anchin, S Subramaniam, J A Glasel, D S Linthicum
Publikováno v: The Journal of Immunology. 146:4248-4257
The structural features of mAb directed against the opiate morphine were analyzed by using competitive ligand analog-binding studies, examination of the V region amino acid sequence, and computer-aided molecular modeling of the fragment V region. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cee66288d065f61e40ec4131cdde7d64
https://doi.org/10.4049/jimmunol.146.12.4248
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2
From outer to inner space: traveling along a scientific career from astrochemistry to drug research
Autor: J A, Glasel
Publikováno v: Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. 57
This professional history describes my journey as a research scientist after my early training and experiences in the pre- and early post-World War II United States. My graduate training concentrated on a problem in astrochemistry: phenomena on comet
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7066f73874e92afe500ea53c0d37ed3d
https://pubmed.ncbi.nlm.nih.gov/11728002
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3
The effects of morphine on cell proliferation
Autor: J A, Glasel
Publikováno v: Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. 55
There is increasing evidence that endogenous opioid peptides ("enkephalins") and other neurotransmitters have widespread, receptor-mediated roles as growth regulators in non-neuronal cells and tissues. For example, it is now believed that enkephalins
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df2f51637448947791494e1162b037ab
https://pubmed.ncbi.nlm.nih.gov/11127966
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4
Hormone-defined cell system for studying G-protein coupled receptor agonist-activated growth modulation: delta-opioid and serotonin-5HT2C receptor activation show opposite mitogenic effects
Autor: D, Agarwal, J A, Glasel
Publikováno v: Journal of cellular physiology. 171(1)
G-protein-coupled receptor (GPCR) agonist-activated transformation of NIH/3T3 fibroblast cells has been documented by many workers. Our present interest is in the growth control exerted by these agonists. The mechanisms involved in GPCR agonist-activ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::65efb46801741af95c339d24724a4198
https://pubmed.ncbi.nlm.nih.gov/9119893
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7
Stereospecificity of opiate receptors in a synchronized culture of NG108-15 cells probed with fluorescent anti-idiotypic antibodies
Autor: M, Ornatowska, J A, Glasel
Publikováno v: Molecular pharmacology. 40(3)
The stereospecificity of the binding of an anti-opiate receptor, anti-idiotypic antibody to receptors on a synchronized NG108-15 neuroblastoma x glioma cell culture has been examined by fluorescence labeling of the antibodies. We had previously found
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e055db50de09dd6d48112aec8752e5b9
https://pubmed.ncbi.nlm.nih.gov/1654512
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8
Analysis of the binding site architecture of monoclonal antibodies to morphine by using competitive ligand binding and molecular modeling
Autor: P H, Kussie, J M, Anchin, S, Subramaniam, J A, Glasel, D S, Linthicum
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 146(12)
The structural features of mAb directed against the opiate morphine were analyzed by using competitive ligand analog-binding studies, examination of the V region amino acid sequence, and computer-aided molecular modeling of the fragment V region. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a2f84b82d0e3d66c7f8f1c4a48ed700
https://pubmed.ncbi.nlm.nih.gov/2040800
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9
Binding studies of polypeptide hormones to bovine neurophysins
Autor: J F McKelvy, J A Glasel
Publikováno v: Journal of Biological Chemistry. 251:2929-2937
Experimental binding isotherms of [9-glycinamide-1-(14)C]oxytocin and [9-glycinamide-1-(14)C]arginine vasopressin to purified neurophysins I and II at pH = 4.4, 5.4, 6.5, 7.4, and 8.5 and 6 degrees, 22 degrees, and 37 degrees in aqueous buffers are r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0381270fbcc0cdef21d07ec8486f85a2
https://doi.org/10.1016/s0021-9258(17)33480-4
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10
A Digital rf Pulse Burst Generator for NMR Relaxation Experiments
Autor: J. A. Glasel, M. Petrinovic, V. Radeka, R. L. Chase
Publikováno v: Review of Scientific Instruments. 41:1766-1770
This paper describes a pulse burst generator designed to provide coherent rf pulse sequences with lengths applicable to NMR relaxation experiments. The burst generator is based on a principle which provides an inherently high on/off ratio. The freque
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70cbe033f1a4b4703395522d420053eb
https://doi.org/10.1063/1.1684406
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