Zobrazeno 1 - 10
of 2 031
pro vyhledávání: '"J A, Gibson"'
Autor:
Adrian Heald, Rui Qin, Camila M. Loureiro, Richard Williams, Chloe Devaney Dopson, J Martin Gibson, Ram Prakash Narayanan, Helene Fachim, Kevin McCay, William Ollier
Publikováno v:
Adipocyte, Vol 12, Iss 1 (2023)
ABSTRACTBackground Weight change is often seen in people with diabetes. We investigated the effects of genes associated with weight change/glucose handling/insulin-signalling.Materials/methods DNA from diabetes individuals and non-diabetes individual
Externí odkaz:
https://doaj.org/article/4a53a2e7371a4d77aa563c1934b5a019
Autor:
McLean L. D. Worsham, Parvathi Nair, J. Randy Gibson, David Rodriguez, Benjamin F. Schwartz, Weston H. Nowlin
Publikováno v:
Frontiers in Ecology and Evolution, Vol 11 (2023)
It is unclear if geographic distributions of animals are behaviorally mediated or simply maintained by ecologically-driven deleterious effects on fitness. Furthermore, it is not well known how behaviors that may affect geographic distributions and re
Externí odkaz:
https://doaj.org/article/28375af91aa642e0b9fc37f9059ca92f
Autor:
Amanda J. W. Gibson, Adrian Box, Winson Y. Cheung, Michelle L. Dean, Anifat A. Elegbede, Desiree Hao, Aliyah Pabani, Randeep Sangha, Dafydd Gwyn Bebb
Publikováno v:
Current Oncology, Vol 29, Iss 3, Pp 1967-1982 (2022)
The use, safety and effectiveness of crizotinib as part of the management of ROS1-rearranged NSCLC patients in a real-world Canadian clinical cohort was the focus of this retrospective review. Twenty-one ROS1-rearranged patients with advanced/metasta
Externí odkaz:
https://doaj.org/article/33b2527c355d4727adee66470c7c3b95
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background Humpless Bos taurus cattle are one of the earliest domestic cattle in Africa, followed by the arrival of humped Bos indicus cattle. The diverse indigenous cattle breeds of Africa are derived from these migrations, with most appear
Externí odkaz:
https://doaj.org/article/e63837c143e14b48a33031977dec333f
Autor:
Helene A. Fachim, Kirk Siddals, Nagaraj Malipatil, Rachelle P Donn, Gabriela YC Moreno, Caroline F Dalton, Safwaan Adam, Handrean Soran, J Martin Gibson, Adrian H Heald
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 96-107 (2020)
Aims: We investigated whether a lifestyle intervention could influence expression and DNA methylation of diabetes-related genes in patients with impaired glucose regulation (IGR), the results were compared to bariatric surgery, considering it an inte
Externí odkaz:
https://doaj.org/article/49a560e0bdf742dda62322bf8a172f6c
Autor:
Helene A. Fachim, Camila M. Loureiro, Kirk Siddals, Caroline F Dalton, Gavin P. Reynolds, J. Martin Gibson, Zhen Bouman Chen, Adrian H. Heald
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 443-453 (2020)
We analysed if levels of four miRNAs would change after a lifestyle intervention involving dietary and exercises in prediabetes. MiRNAs previously shown to be associated with diabetes (Let-7a, Let-7e, miR-144 and miR-92a) were extracted from serum pr
Externí odkaz:
https://doaj.org/article/a32d02250bf248a7aaeeb77bf5f8f5a1
Autor:
Paul M. Wilson, Samantha Dixon, Tracey Vell, Peter Bower, Linda Rootkin, Claire Williams, Adam Strong, David Lawrence, Rebecca Elvey, Owen Williams, Norman Stein, J. Martin Gibson
Publikováno v:
International Journal of Clinical Trials. 10:156-165
Background: Translational gaps exist in implementing health innovations rapidly in clinical practice. Pragmatic effectiveness and implementation studies, therefore, play a pivotal role in understanding how high-value health innovations could be deplo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a18899662bda4ba8ef8c3159562d063
https://doi.org/10.18203/2349-3259.ijct20231106
https://doi.org/10.18203/2349-3259.ijct20231106
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Elevated rates of evolution in reproductive proteins are commonly observed in animal species, and are thought to be driven by the action of sexual selection and sexual conflict acting specifically on reproductive traits. Whether similar patterns are
Externí odkaz:
https://doaj.org/article/2a8877a11a3e4b9c8b34502e1a6421b1
Autor:
Helene A. Fachim, Nagaraj Malipatil, Kirk Siddals, Rachelle Donn, Gabriela Y. Cortés, Caroline F. Dalton, J. Martin Gibson, Adrian H. Heald
Publikováno v:
Epigenomes, Vol 6, Iss 1, p 7 (2022)
BDNF signalling in hypothalamic neuronal circuits is thought to regulate mammalian food intake. In light of this, we investigated how a lifestyle intervention influenced serum levels and DNA methylation of BDNF gene in fat tissue and buffy coat of ND
Externí odkaz:
https://doaj.org/article/db21d75df4dd47a4866f820293d6ca91
Autor:
J Paul Gibson, Dominique Méry
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 271, Iss Proc. IMPEX 2017 and FM&MDD 2017, Pp 64-79 (2018)
The increasing development of cyber-physical systems (CPSs) requires modellers to represent and reason about physical values. This paper addresses two major, inter-related, aspects that arise when modelling physical measures. Firstly, there is often
Externí odkaz:
https://doaj.org/article/111e2ff62119471c8648b19d7ad47ee6