Zobrazeno 1 - 10
of 1 325
pro vyhledávání: '"J A, Fischer"'
Autor:
Styliani I. Kampezidou, Archana Tikayat Ray, Anirudh Prabhakara Bhat, Olivia J. Pinon Fischer, Dimitri N. Mavris
Publikováno v:
Eng, Vol 5, Iss 1, Pp 384-416 (2024)
This paper offers a comprehensive examination of the process involved in developing and automating supervised end-to-end machine learning workflows for forecasting and classification purposes. It offers a complete overview of the components (i.e., fe
Externí odkaz:
https://doaj.org/article/3a4d12e11bf54d67a46bbd9e48785f32
Publikováno v:
Geoscientific Model Development, Vol 16, Pp 7013-7035 (2023)
Simulation tools are important to investigate and predict mobility and the destructive potential of gravitational mass flows (e.g., snow avalanches). AvaFrame – the open avalanche framework – offers well-established computational modeling approac
Externí odkaz:
https://doaj.org/article/c92b5838236e404d884498d506cfef1a
Autor:
Clara Hoebart, Attila Kiss, Bruno K. Podesser, Ammar Tahir, Michael J. M. Fischer, Stefan Heber
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1856 (2024)
Sensory neurons densely innervate the myocardium. The role of their sensing and response to acute and prolonged ischemia is largely unclear. In a cellular model of ischemia-reperfusion injury, the presence of sensory neurons increases cardiomyocyte s
Externí odkaz:
https://doaj.org/article/469a13a58cf1415ba0a0cfae8f9302e2
Autor:
Friedrich Reusswig, Matthias Dille, E. Krüger, J. Ortscheid, Tobias Feige, S. Gorressen, J.-W. Fischer, Margitta Elvers
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionPlatelets play an important role in cardiovascular diseases. After acute myocardial infarction, platelets display enhanced activation and migrate into the infarct zone. Furthermore, platelets trigger acute inflammation and cardiac remodel
Externí odkaz:
https://doaj.org/article/5e8cc26c7bb64841915ebad161af2c16
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-22 (2023)
Abstract Shape optimization is an indispensable step in any aerodynamic design. However, the inherent complexity and non-linearity associated with fluid mechanics as well as the high-dimensional design space intrinsic to such problems make airfoil sh
Externí odkaz:
https://doaj.org/article/9ad64860ffe943aeac020828fea41aa2
Autor:
Maximilian L. Mager, Cosmin I. Ciotu, Markus Gold-Binder, Stefan Heber, Michael J. M. Fischer
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background and purpose: Addition of preservatives ensures microbial stability, especially in multidose containers of parenterally administered pharmaceuticals. These compounds can cause side effects, and particularly at the site of application, might
Externí odkaz:
https://doaj.org/article/c51bb090e4e2499a9a964c7420623a01
Autor:
C. Binsch, D. M. Barbosa, G. Hansen-Dille, M. Hubert, S. M. Hodge, M. Kolasa, K. Jeruschke, J. Weiß, C. Springer, S. Gorressen, J. W. Fischer, M. Lienhard, R. Herwig, S. Börno, B. Timmermann, A. L. Cremer, H. Backes, A. Chadt, H. Al-Hasani
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-14 (2023)
Abstract Background Type 2 Diabetes mellitus (T2DM) is a major risk factor for cardiovascular disease and associated with poor outcome after myocardial infarction (MI). In T2DM, cardiac metabolic flexibility, i.e. the switch between carbohydrates and
Externí odkaz:
https://doaj.org/article/1aa009e1fee843359a7e115e04fb7872
Autor:
Saskia Wedel, Praveen Mathoor, Oliver Rauh, Tim Heymann, Cosmin I. Ciotu, Dominik C. Fuhrmann, Michael J. M. Fischer, Andreas Weigert, Natasja de Bruin, Felix Hausch, Gerd Geisslinger, Marco Sisignano
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-21 (2022)
Abstract Background Neuropathic pain is experienced worldwide by patients suffering from nerve injuries, infectious or metabolic diseases or chemotherapy. However, the treatment options are still limited because of low efficacy and sometimes severe s
Externí odkaz:
https://doaj.org/article/a1ae3ff5437d4071b8e640f89f13be07
Autor:
C. J. L. D'Amboise, M. Neuhauser, M. Teich, A. Huber, A. Kofler, F. Perzl, R. Fromm, K. Kleemayr, J.-T. Fischer
Publikováno v:
Geoscientific Model Development, Vol 15, Pp 2423-2439 (2022)
Models and simulation tools for gravitational mass flows (GMFs) such as snow avalanches, rockfall, landslides, and debris flows are important for research, education, and practice. In addition to basic simulations and classic applications (e.g., haza
Externí odkaz:
https://doaj.org/article/b787a8f3216948e9afe1b76da372d00c
Autor:
Tina Blažević, Cosmin I Ciotu, Markus Gold-Binder, Elke H Heiss, Michael J M Fischer, Verena M Dirsch
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281191 (2023)
We showed previously that capsaicin, an active compound of chili peppers, can inhibit platelet-derived growth factor-induced proliferation in primary rat vascular smooth muscle cells (VSMCs). The inhibition of BrdU incorporation by capsaicin in these
Externí odkaz:
https://doaj.org/article/4bd5b2936b62482d8e4c4cff87d4e85c