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pro vyhledávání: '"J A, Desoto"'
Autor:
Elizabeth B, Fryar-Tita, Jharna R, Das, J H, Davis, J A, Desoto, Sidney, Green, William M, Southerland, Donnell, Bowen
Publikováno v:
Anticancer research. 27(3B)
Breast cancer patients are at increased risk of osteoporosis. Contributing factors include age and/or chemotherapy. The selective estrogen modulator, raloxifene (RAL), effective in the prevention of breast cancer and approved for the treatment and pr
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 53(3)
These studies were designed to develop procedures that would capitalize on the growth inhibitory effects of tamoxifen (Tam) and methotrexate (MTX) in breast cancer, while protecting bone marrow with a priming dose of 5-fluorouracil (5-FU). High-dose
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 49(7)
Faslodex (FAS, ICI 182, 780), a novel steroidal estrogen antagonist decreased high-dose methotrexate (MTX) cytotoxicity in MCF-7 breast cancer cells. When FAS is given at least 24 hr prior to MTX, the resultant interaction is antagonistic. However, w