Zobrazeno 1 - 10
of 19
pro vyhledávání: '"J A, Carmical"'
Autor:
Benjamin B Gelman, Tiansheng Chen, Joshua G Lisinicchia, Vicki M Soukup, J Russ Carmical, Jonathan M Starkey, Eliezer Masliah, Deborah L Commins, Dianne Brandt, Igor Grant, Elyse J Singer, Andrew J Levine, Jeremy Miller, Jessica M Winkler, Howard S Fox, Bruce A Luxon, Susan Morgello, National NeuroAIDS Tissue Consortium
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46178 (2012)
The National NeuroAIDS Tissue Consortium (NNTC) performed a brain gene expression array to elucidate pathophysiologies of Human Immunodeficiency Virus type 1 (HIV-1)-associated neurocognitive disorders.Twenty-four human subjects in four groups were e
Externí odkaz:
https://doaj.org/article/d2dde98821204c7c886132f862d05bce
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47301 (2012)
Ixodes species ticks are competent vectors of tick-borne viruses including tick-borne encephalitis and Powassan encephalitis. Tick saliva has been shown to facilitate and enhance viral infection. This likely occurs by saliva-mediated modulation of ho
Externí odkaz:
https://doaj.org/article/eb96a1695bbc42caaa2b328447d44ab7
Autor:
Barry Rockx, Olivier Escaffre, Viktoriya Borisevich, J. Russ Carmical, Deborah Prusak, Heinz Feldmann, Joseph Prescott
Publikováno v:
Journal of Virology. 87:3284-3294
Hendra virus (HeV) and Nipah virus (NiV) are deadly zoonotic viruses for which no vaccines or therapeutics are licensed for human use. Henipavirus infection causes severe respiratory illness and encephalitis. Although the exact route of transmission
Cognitive Enhancement with Rosiglitazone Links the Hippocampal PPARγ and ERK MAPK Signaling Pathways
Autor:
Sigmund J. Haidacher, Jordan B. Jahrling, Jennifer Rodriguez-Rivera, Kelly T. Dineley, Rovshan G. Sadygov, Yingxin Zhao, J. Russ Carmical, Caterina M. Hernandez, Jonathan M. Starkey, Heidi Spratt, Bruce A. Luxon, Thomas G. Wood, Larry Denner
Publikováno v:
The Journal of Neuroscience. 32:16725-16735
We previously reported that the peroxisome proliferator-activated receptor γ (PPARγ) agonist rosiglitazone (RSG) improved hippocampus-dependent cognition in the Alzheimer's disease (AD) mouse model, Tg2576. RSG had no effect on wild-type littermate
Autor:
Kirk L. Ives, Judith F. Aronson, Clarisse D. Djukom, J. Russ Carmical, Guillermo Gomez, Thomas G. Wood, Mark R. Hellmich, Celia Chao
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Experimental data indicate that colorectal cancer cells with CD133 expression exhibit enhanced tumorigenicity over CD133-negative (CD133-) cells. We hypothesized that CD133-positive (CD133+) cells, compared with CD133-, are more tumorigenic because t
Autor:
Thomas G. Wood, Brian Lowell, Daniel L. Marks, Irena B. King, Amanda K. McCullough, Vladimir Vartanian, Deborah Prusak, J. Russ Carmical, Ayesha K. Batra, Harini Sampath, Lloyd R. Stephen, Lauriel F. Earley
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 300:E724-E734
Exposure to chronic and acute oxidative stress is correlated with many human diseases, including, but not limited to, cancer, heart disease, diabetes, and obesity. In addition to cellular lipids and proteins, cellular oxidative stress can result in d
Publikováno v:
European review for medical and pharmacological sciences. 19(20)
Niacin, activating G-protein coupled receptor (GPR) 109A, stimulates release of vasodilatory prostaglandins (PGs) such as PGE2 which can elicit niacin-associated flushing side effects. Poly-lactic-co-glycolic acid (PLGA) and poly-lactic acid (PLA) ar
Autor:
Yue Zou, Bennett Van Houten, Constance M. Harris, Thomas M. Harris, R. Stephen Lloyd, Agnieszka Kowalczyk, J. Russ Carmical
Publikováno v:
Biochemistry. 41:3109-3118
A general protocol for preparation of oligonucleotides containing intrastrand cross-links between the exocyclic amino groups of adjacent deoxyguanosines has been developed. A series of 2, 3, and 4 methylene cross-links was incorporated site-specifica
Autor:
Francisco J. Alarcon-Chaidez, Judith F. Aronson, Stephen K. Wikel, Dar M. Heinze, Saravanan Thangamani, J. Russ Carmical
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 5 (2014)
Frontiers in Microbiology, Vol 5 (2014)
Tick salivary glands produce complex cocktails of bioactive molecules that facilitate blood feeding and pathogen transmission by modulating host hemostasis, pain/itch responses, wound healing, and both innate and adaptive immunity. In this study, cut
Autor:
Constance M. Harris, Bennett Van Houten, J. Russ Carmical, Agnieszka Kowalczyk, R. Stephen Lloyd, Yue Zou, Lubomir V. Nechev, Thomas M. Harris
Publikováno v:
Journal of Biological Chemistry. 275:19482-19489
To initiate studies designed to identify the mutagenic spectrum associated with butadiene diepoxide-induced N(2)-N(2) guanine intrastrand cross-links, site specifically adducted oligodeoxynucleotides were synthesized in which the adducted bases were