Zobrazeno 1 - 10
of 1 834
pro vyhledávání: '"J A, Cameron"'
Autor:
Christopher J. F. Cameron, Sebastian J. H. Seager, Fred J. Sigworth, Hemant D. Tagare, Mark B. Gerstein
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Cryo-EM particle identification from micrographs (“picking”) is challenging due to the low signal-to-noise ratio and lack of ground truth for particle locations. State-of-the-art computational algorithms (“pickers”) identify differen
Externí odkaz:
https://doaj.org/article/fe00cb92b6fb48f3bf722ecef3f5348e
Autor:
Calum Macdonald, Norah Palmateer, Andrew McAuley, Laura Lindsay, Taimoor Hasan, Safraj Shahul Hameed, Elliot Hall, Karen Jeffrey, Zoë Grange, Petros Gousias, Sally Mavin, Lisa Jarvis, J. Claire Cameron, Luke Daines, Holly Tibble, Colin R. Simpson, Colin McCowan, Srinivasa Vittal Katikireddi, Igor Rudan, Adeniyi Francis Fagbamigbe, Lewis Ritchie, Ben Swallow, Paul Moss, Chris Robertson, Aziz Sheikh, Josie Murray
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Several population-level studies have described individual clinical risk factors associated with suboptimal antibody responses following COVID-19 vaccination, but none have examined multimorbidity. Others have shown that suboptimal post-vacc
Externí odkaz:
https://doaj.org/article/76e8b5eedf624decac9fa914f76328ac
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2024)
Hi-C is one of the most widely used approaches to study three-dimensional genome conformations. Contacts captured by a Hi-C experiment are represented in a contact frequency matrix. Due to the limited sequencing depth and other factors, Hi-C contact
Externí odkaz:
https://doaj.org/article/f5cebd6f57544fea9b82ee960cee3fc2
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT The United Kingdom implemented the first national infant immunization schedule for the meningococcal vaccine 4CMenB (Bexsero) in September 2015, targeting serogroup B invasive meningococcal disease (IMD). Bexsero contains four variable subca
Externí odkaz:
https://doaj.org/article/58c7b71d79344770875b3c58aec4cb9d
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-4 (2020)
Abstract Objective Ligation-Mediated Amplification (LMA) is a versatile biochemical tool for amplifying selected DNA sequences. LMA has increased in popularity due to its integration within chromosome conformation capture (5C) and chromatin immunopre
Externí odkaz:
https://doaj.org/article/10f3daefd8bf451497c7b8ba1859c0bb
Autor:
Alessandro Bonetti, Federico Agostini, Ana Maria Suzuki, Kosuke Hashimoto, Giovanni Pascarella, Juliette Gimenez, Leonie Roos, Alex J. Nash, Marco Ghilotti, Christopher J. F. Cameron, Matthew Valentine, Yulia A. Medvedeva, Shuhei Noguchi, Eneritz Agirre, Kaori Kashi, Samudyata, Joachim Luginbühl, Riccardo Cazzoli, Saumya Agrawal, Nicholas M. Luscombe, Mathieu Blanchette, Takeya Kasukawa, Michiel de Hoon, Erik Arner, Boris Lenhard, Charles Plessy, Gonçalo Castelo-Branco, Valerio Orlando, Piero Carninci
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Mammalian genomes encode tens of thousands of ncRNAs that have important roles in regulation of gene expression and chromatin organization. Here, the authors present RADICLseq to map RNA-chromatin interactions in intact nuclei to shed light on these
Externí odkaz:
https://doaj.org/article/3ee35708eeee438bbb6649cdd0169ea5
Autor:
Fiona McQuaid, Rachel Mulholland, Yuma Sangpang Rai, Utkarsh Agrawal, Helen Bedford, J Claire Cameron, Cheryl Gibbons, Partho Roy, Aziz Sheikh, Ting Shi, Colin R Simpson, Judith Tait, Elise Tessier, Steve Turner, Jaime Villacampa Ortega, Joanne White, Rachael Wood
Publikováno v:
PLoS Medicine, Vol 19, Iss 2, p e1003916 (2022)
BackgroundIn 2020, the SARS-CoV-2 (COVID-19) pandemic and lockdown control measures threatened to disrupt routine childhood immunisation programmes with early reports suggesting uptake would fall. In response, public health bodies in Scotland and Eng
Externí odkaz:
https://doaj.org/article/9dabc46c55454052ac1fd97b754e9a11
Autor:
Natalie S. Shenker, Alvaro Perdones-Montero, Adam Burke, Sarah Stickland, Julie A. K. McDonald, Simon J. S. Cameron
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1069 (2022)
Given the long-term advantages of exclusive breastfeeding to infants and their mothers, there is both an individual and public health benefit to its promotion and support. Data on the composition of human milk over the course of a full period of lact
Externí odkaz:
https://doaj.org/article/9423c738c1b547bbb78646dcd8daafd1
Autor:
Xue Qing David Wang, Christopher J. F. Cameron, Denis Paquette, Dana Segal, Reid Warsaba, Mathieu Blanchette, Josée Dostie
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background Understanding how transcription occurs requires the integration of genome-wide and locus-specific information gleaned from robust technologies. Chromatin immunoprecipitation (ChIP) is a staple in gene expression studies, and while
Externí odkaz:
https://doaj.org/article/c42efafcb2e14cee9062b99d184e3af9
Autor:
Charlene M.C. Rodrigues, Jay Lucidarme, Ray Borrow, Andrew Smith, J. Claire Cameron, E. Richard Moxon, Martin C.J. Maiden
Publikováno v:
Emerging Infectious Diseases, Vol 24, Iss 4, Pp 673-682 (2018)
In September 2015, 4CMenB meningococcal vaccine was introduced into the United Kingdom infant immunization program without phase 3 trial information. Understanding the effect of this program requires enhanced surveillance of invasive meningococcal di
Externí odkaz:
https://doaj.org/article/51f8d8e8518346738f25f7c3d8ce08e1