Zobrazeno 1 - 10
of 32
pro vyhledávání: '"J A, Axelson"'
Autor:
D. Gåsvaer, J. Von Axelson
Considering today-s increasing speed of change, radical and innovative improvement - Kaikaku, is a necessity parallel to continuous incremental improvement - Kaizen, especially for SME-s in order to attain the competitive edge needed to be profitable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d3b60d881e87e63aaa73a6a803e5f8
Autor:
J, Peter, H, Burbach, R A, Adan, H H, Tol, M A, Verbeeck, J F, Axelson, F W, Leeuwen, J M, Beekman, G, Ab
Publikováno v:
Journal of neuroendocrinology. 2(5)
Oxytocin (OT) plays a role in reproduction at the level of the pituitary and mammary glands and uterus. This OT is synthesized in the hypothalamo-neurohypophyseal system (HNS). A number of observations have suggested that estrogens regulate the produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbd7f80c73c1b421256909598533a65c
https://pubmed.ncbi.nlm.nih.gov/19215399
https://pubmed.ncbi.nlm.nih.gov/19215399
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(2)
Previous estimates of maternal and fetal placental and nonplacental clearances in pregnant sheep using a two-compartment open model have revealed higher values of fetal placental clearance (CLfm) compared to the maternal placental clearance (CLmf) fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f7ed49c2bd64e01bae1485a105888b1
https://pubmed.ncbi.nlm.nih.gov/9262323
https://pubmed.ncbi.nlm.nih.gov/9262323
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(3)
In this study, two factors that could affect fetal drug exposure were examined: 1) the extent of elimination of drug delivered to the fetal liver from the placenta via the umbilical vein; and 2) the degree to which there is preferential distribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7baa41a36ed3abe1fad76db00fa748c1
https://pubmed.ncbi.nlm.nih.gov/8820416
https://pubmed.ncbi.nlm.nih.gov/8820416
Publikováno v:
NIDA research monograph. 154
The development of more sensitive and selective analytical techniques has greatly improved scientists' ability to study the PK, PD, and metabolism of drugs in pregnancy. This chapter has chronicled the evolution of the study of drug disposition in pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::714c49dcbdc439afef25f9c899846aad
https://pubmed.ncbi.nlm.nih.gov/8606744
https://pubmed.ncbi.nlm.nih.gov/8606744
Autor:
K, Yeleswaram, D W, Rurak, E, Kwan, C, Hall, A, Doroudian, M R, Wright, F S, Abbott, J E, Axelson
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(1)
Labetalol has been previously shown to cause significant maternal and fetal metabolic effects in pregnant sheep after maternal administration. To investigate these observations further, the present study describes the pharmacokinetics, metabolism and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f08c805ef7f5813c175a7aa84e3f3ba
https://pubmed.ncbi.nlm.nih.gov/8229771
https://pubmed.ncbi.nlm.nih.gov/8229771
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 21(2)
Labetalol causes significant maternal and fetal metabolic effects in pregnant sheep (Yeleswaram et al., J. Pharmacol. Exp. Ther. 262, 683-691 (1992)). This study was undertaken to investigate the contribution of skeletal muscles in the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b025427f502e1b0aab5e60df1ad2889f
https://pubmed.ncbi.nlm.nih.gov/8097698
https://pubmed.ncbi.nlm.nih.gov/8097698
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(2)
The maternal-fetal disposition of labetalol, a combined alpha-1 and beta adrenergic blocker, and its pharmacodynamics in pregnancy are not well understood. This study describes the pharmacokinetics, cardiovascular and metabolic effects of labetalol i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb390de6183e8bd77d2a0e0bcae1523d
https://pubmed.ncbi.nlm.nih.gov/1501116
https://pubmed.ncbi.nlm.nih.gov/1501116
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(1)
Ritodrine infusion to fetal lambs causes numerous metabolic perturbations including hypoxemia. To investigate these changes further and to elucidate a mechanism for the development of hypoxemia, ritodrine was infused at rate of 2.6 micrograms/min int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f93005c30d5e44ed7c9bfb2448ab6fd
https://pubmed.ncbi.nlm.nih.gov/1625213
https://pubmed.ncbi.nlm.nih.gov/1625213
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 258(3)
The disposition of the beta-2 adrenoreceptor agonist, ritodrine, has been examined in the fetal lamb during and after constant rate fetal intravenous infusion (8-24 h). Samples were collected from the fetal femoral artery, umbilical vein, maternal fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcbb4ee42bfb9eaab241df812a568d8f
https://pubmed.ncbi.nlm.nih.gov/1890624
https://pubmed.ncbi.nlm.nih.gov/1890624