Zobrazeno 1 - 7
of 7
pro vyhledávání: '"J A, Aguirre Ghiso"'
Publikováno v:
Medicina. 60
Deregulation of several signaling pathways have been found to be critical for the development of different types of tumors, both in transgenic and spontaneous models. The role of proteases and adhesion molecules during the early stages of tumor progr
Autor:
A J, Urtreger, J A, Aguirre Ghiso, S E, Werbajh, L I, Puricelli, A F, Muro, E, Bal de Kier Joff
Publikováno v:
International journal of cancer. 82(5)
Tumor invasion and metastasis development is a multistep process involving adhesion molecules as well as tumor proteases. It has been reported that tumor cells lacking fibronectin (FN) expression and engineered to re-express FN showed a marked reduct
Publikováno v:
International journal of cancer. 78(6)
The invasion and metastasis process involves degradation of the extracellular matrix mediated by tumor- and host-produced proteolytic enzymes. The main enzymes involved in this process are urokinase-type plasminogen activator (uPA) and the matrix met
Publikováno v:
International journal of cancer. 76(3)
Urokinase-type plasminogen activator (uPA) is a key serine protease involved in invasion and metastasis. We had shown that overproduction of uPA in tumor cells is controlled by a phospholipase D-protein kinase C-dependent pathway. Now we studied whet
Publikováno v:
International journal of cancer. 71(5)
Spreading is a critical process involved in motility and growth of tumor cells during the metastatic cascade. Focal adhesion kinase, src-proteins and PKC have been reported to participate in the regulation of cytoskeleton organization in both normal
Autor:
I S D'Elia, Miriam J. Diament, E. Bal de Kier Joffé, J. A. Aguirre Ghiso, Slobodanka M. Klein
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 18(1)
We studied the effect of tumoral microenvironments on metastatic phenotypes. Therefore, murine mammary adenocarcinoma cells cultured in vivo in diffusion chambers (DC) were implanted intraperitoneally in BALB/c mice. The behavior of DC-cultured cells
Autor:
Patricia V. Elizalde, Ruth Lupu, Omar Pedro Pignataro, E. Bal de Kier Joffé, L. Puricelli, J. A. Aguirre Ghiso, Mariana Salatino, Cecilia J. Proietti, Leticia Labriola, María Eugenia Balañá, Eduardo H. Charreau
Publikováno v:
International Journal of Cancer. 117:1065-1065