Zobrazeno 1 - 10
of 406
pro vyhledávání: '"J A, Abraham"'
Autor:
Senthilkumar Preethy, Yoshitsugu Aoki, Katsura Minegishi, Masaru Iwasaki, Rajappa Senthilkumar, Samuel J. K. Abraham
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Recent advances in the management of Duchenne muscular dystrophy (DMD), such as exon skipping and gene therapy, though have reached a clinical stage, the outcome at its best is still considered suboptimal. In this study, we evaluated a novel
Externí odkaz:
https://doaj.org/article/23a43cb8b1bd40839261f0f0f32c9f0f
Autor:
M. Hayashi, N. Salvetat, C. Cayzac, F. J. Checa-Robles, C. Lozano, J.-D. Abraham, B. Dubuc, S. Mereuze, J. V. Nani, F. Molina, E. Brietske, D. Weissmann
Publikováno v:
European Psychiatry, Vol 66, Pp S573-S573 (2023)
Introduction Bipolar disorder (BD) is a severe mental disorder associated with functional impairment, high disability and premature mortality. Modifications of editing in mRNA of serotonin receptor subtype 2C (5-HTR2c) was reported by us in depressed
Externí odkaz:
https://doaj.org/article/d2a05c1d3d224aa98d5c71213c737bc6
Autor:
Shojiro Katoh, Atsuki Fujimaru, Masaru Iwasaki, Hiroshi Yoshioka, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel J. K. Abraham
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Regenerative medicine applications require cells that are not inflicted with senescence after in vitro culture for an optimal in vivo outcome. Methods to overcome replicative senescence include genomic modifications which have their own disa
Externí odkaz:
https://doaj.org/article/b5c0cbb496654a6aaf0d40704c94d2db
Autor:
Naoki Yamamoto, Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Nobunao Ikewaki, Masaru Iwasaki, Senthilkumar Preethy, Gary A Levy, Subramaniam Srinivasan, Natarajan Ranganathan, Rajappa Senthilkumar, Samuel J K Abraham
Publikováno v:
BMJ Open Gastroenterology, Vol 9, Iss 1 (2022)
Objective The gut microbiome and its metabolites are influenced by age and stress and reflect the metabolism and health of the immune system. We assessed the gut microbiota and faecal metabolome in a static animal model of non-alcoholic steatohepatit
Externí odkaz:
https://doaj.org/article/0eb185c28c3e4abb8a7b4a64c421ca48
Autor:
J.-D. Abraham, N. Salvetat, P. Guerra, M. Ferrari, P. Le Guen, O. Biglia, C. Henry, L. Kessing, J.M. Haro, E. Vieta, D. Weissmann
Publikováno v:
European Psychiatry, Vol 65, Pp S413-S413 (2022)
Introduction Bipolar disorder (BD) is a psychiatric disorder characterized by alternating episodes of high mood and low mood similar to depression. To differentiate BD patients from unipolar (UN) depressed patients remains a challenge and the clinica
Externí odkaz:
https://doaj.org/article/fa44bd0acea042d9a390bcf228049e16
Autor:
Senthilkumar Preethy, Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Vaddi Surya Prakash, Nobunao Ikewaki, Yasunori Ikeue, Mitsuru Nagataki, Masaru Iwasaki, Rajappa Senthilkumar, Samuel J. K. Abraham
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Sepsis is a life-threatening condition caused by an abnormal immune response induced by infection with no approved or specific therapeutic options. We present our perspectives for the therapeutic management of sepsis through a four-way approach: (1)
Externí odkaz:
https://doaj.org/article/d5f123f3c3664c2fae7ff026758f2468
Autor:
Nobunao Ikewaki, Kosagi-Sharaf Rao, Armando Durant Archibold, Masaru Iwasaki, Rajappa Senthilkumar, Senthilkumar Preethy, Shojiro Katoh, Samuel J. K. Abraham
Publikováno v:
Thrombosis Journal, Vol 18, Iss 1, Pp 1-8 (2020)
Abstract Direct endothelial injury by viruses and dysregulation of clotting mechanisms due to cytokine storm are the major precipitating factors of mortality in COVID-19; both are attributed to a fundamental dysregulation of the immune system. While
Externí odkaz:
https://doaj.org/article/ab30bb5b0f5c47509388dbfdf1431904
Autor:
J.-D. Abraham, N. Salvetat, F. Checa-Robles, V. Patel, C. Cayzac, B. Dubuc, D. Vetter, J.-P. Lang, P. Courtet, D. Kupfer, D. Weissmann
Publikováno v:
European Psychiatry, Vol 64, Pp S77-S78 (2021)
Introduction In clinical practice, differentiating Bipolar Disorder (BD) from unipolar depression is challenging due to the depressive symptoms, which are the core presentations of both disorders. Patients with BD are often misdiagnosed during depres
Externí odkaz:
https://doaj.org/article/a11bf59ccc4846dca2d57c38599f1bd9
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/ce3eb9496378408d88b56025984e44fe
Autor:
Rajappa Senthilkumar, Hiroshi Yoshioka, Shojiro Katoh, Masaru Iwasaki, Vaddi Surya Prakash, Madasamy Balamurugan, Vidyasagar Devaprasad Dedeepiya, Senthilkumar Preethy, Samuel J. K. Abraham
Publikováno v:
Current Eye Research. 48:564-572