Zobrazeno 1 - 10
of 1 374
pro vyhledávání: '"J . Edmonds"'
Autor:
George E. Ronson, Katarzyna Starowicz, Elizabeth J. Anthony, Ann Liza Piberger, Lucy C. Clarke, Alexander J. Garvin, Andrew D. Beggs, Celina M. Whalley, Matthew J. Edmonds, James F. J. Beesley, Joanna R. Morris
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract A synthetic lethal relationship exists between disruption of polymerase theta (Polθ), and loss of either 53BP1 or homologous recombination (HR) proteins, including BRCA1; however, the mechanistic basis of these observations are unclear. Her
Externí odkaz:
https://doaj.org/article/9fe50622466f46da85132eed80fe32f1
Autor:
Shenping Liu, Ruth F. Sommese, Nicole L. Nedoma, Lucy Mae Stevens, Jason K. Dutra, Liying Zhang, David J. Edmonds, Yang Wang, Michelle Garnsey, Michelle F. Clasquin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Hydroxysteroid 17-beta-dehydrogenase 13 (HSD17B13) is a hepatic lipid droplet-associated enzyme that is upregulated in patients with non-alcoholic fatty liver disease. Recently, there have been several reports that predicted loss of function
Externí odkaz:
https://doaj.org/article/749817982a194a3cbe9e946b62e48e24
Autor:
K. Calvin, P. Patel, L. Clarke, G. Asrar, B. Bond-Lamberty, R. Y. Cui, A. Di Vittorio, K. Dorheim, J. Edmonds, C. Hartin, M. Hejazi, R. Horowitz, G. Iyer, P. Kyle, S. Kim, R. Link, H. McJeon, S. J. Smith, A. Snyder, S. Waldhoff, M. Wise
Publikováno v:
Geoscientific Model Development, Vol 12, Pp 677-698 (2019)
This paper describes GCAM v5.1, an open source model that represents the linkages between energy, water, land, climate, and economic systems. GCAM is a market equilibrium model, is global in scope, and operates from 1990 to 2100 in 5-year time steps.
Externí odkaz:
https://doaj.org/article/642aab5086f643809c8517d29836df58
Publikováno v:
Respiratory Medicine Case Reports, Vol 29, Iss , Pp - (2020)
There are growing reports of adverse health effects from e-cigarette use or vaping. The U.S. Centers for Disease Control and Prevention has reported 2409 cases and 52 deaths associated with e-cigarette use as of December 10, 2019. Vaping has been ass
Externí odkaz:
https://doaj.org/article/65de85fe60064a5b9be856c0f56ed78d
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Palmitoylation is a reversible post-translational protein modification in which palmitic acid is added to cysteine residues, allowing association with different cellular membranes and subdomains. Recently, techniques have been developed to i
Externí odkaz:
https://doaj.org/article/7f3e84c68ff34038ae54030f230a9716
Autor:
Sujatha Thyagarajan, Naomi J Edmonds
Publikováno v:
Journal of Pediatric Critical Care, Vol 4, Iss 1, Pp 30-36 (2017)
Hemorrhagic shock is a preventable mortality in pediatric trauma. Assessment and management requires an understanding of the patho-physiogical processes specific to children. The key to successful management of hemorrhagic shock in trauma is rapid as
Externí odkaz:
https://doaj.org/article/a6ee35911f144896a9a880edf44d1fa7
Autor:
Brigitte Vollmer, Caroline J. Edmonds
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Children who were growth restricted in utero (FGR) and are born small for gestational age (SGA) may experience poorer long term neurological and cognitive outcomes. Those also born preterm may have particular difficulties. The objective of this paper
Externí odkaz:
https://doaj.org/article/7ea7a728f41e40f49e94a59492f72068
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210568 (2019)
Adequate provision of safe water, basic sanitation, and hygiene (WASH) facilities and behavior change can reduce pupil absence and infectious disease. Increased drinking water quantity may also improve educational outcomes through the effect of hydra
Externí odkaz:
https://doaj.org/article/347998a3c87648d692e6321b0bf8fdde
Publikováno v:
Europace. 25
Funding Acknowledgements Type of funding sources: None. Introduction Zio XT is a recent technology that has enabled automated heart rhythm analysis using an artificial intelligence-based algorithm. It can be fitted by patients and record the heart rh
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