Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jűrgen Westermann"'
Autor:
Martin Meinhardt, Cornelia Tune, Lisa-Kristin Schierloh, Andrea Schampel, René Pagel, Jürgen Westermann
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0273264 (2022)
Large cellular antigens comprise a variety of different epitopes leading to a T cell response of extreme diversity. Therefore, tracking such a response by next generation sequencing of the T cell receptor (TCR) in order to identify common TCR propert
Externí odkaz:
https://doaj.org/article/2bab8932c4264ccf87e822f1642f5f5f
Publikováno v:
BMC Medical Education, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Most medical students in Germany are admitted via selection procedures, which are adjusted to the demands of the universities. At Lübeck medical school, scores from interviews that measure non-academic skills and pre-university G
Externí odkaz:
https://doaj.org/article/941b42cfa2b3420382adb065f5ac2d2a
Autor:
Markus Niebuhr, Julia Belde, Anke Fähnrich, Arnauld Serge, Magali Irla, Christoph T Ellebrecht, Christoph M Hammers, Katja Bieber, Jürgen Westermann, Kathrin Kalies
Publikováno v:
eLife, Vol 10 (2021)
Follicular T helper cells (Tfh) are a specialized subset of CD4 effector T cells that are crucial for germinal center (GC) reactions and for selecting B cells to undergo affinity maturation. Despite this central role for humoral immunity, only few da
Externí odkaz:
https://doaj.org/article/5c629f812223404cac261caf6eb8a22c
Autor:
Anke Fähnrich, Sebastian Klein, Arnauld Sergé, Christin Nyhoegen, Sabrina Kombrink, Steffen Möller, Karsten Keller, Jürgen Westermann, Kathrin Kalies
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
CD154 is a transmembrane cytokine expressed transiently on activated CD4 T cells upon T-cell receptor (TCR) stimulation that interacts with CD40 on antigen-presenting cells. The signaling via CD154:CD40 is essential for B-cell maturation and germinal
Externí odkaz:
https://doaj.org/article/84eee5ff2f684e0690d46981007d089b
Autor:
Claudia Stamm, Julia Barthelmann, Natalia Kunz, Kai-Michael Toellner, Jürgen Westermann, Kathrin Kalies
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67746 (2013)
The differentiation of CD4 T cells into Th1 and Th2 cells in vivo is difficult to analyze since it is influenced by many factors such as genetic background of the mice, nature of antigen, and adjuvant. In this study, we used a well-established model,
Externí odkaz:
https://doaj.org/article/f6760b81023c46cb82c4b72d6bfc0887
Autor:
Thomas Bollinger, Anton Leutz, Alexei Leliavski, Ludmila Skrum, Judit Kovac, Luigi Bonacina, Christian Benedict, Tanja Lange, Jürgen Westermann, Henrik Oster, Werner Solbach
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29801 (2011)
Though it has been shown that immunological functions of CD4+ T cells are time of day-dependent, the underlying molecular mechanisms remain largely obscure. To address the question whether T cells themselves harbor a functional clock driving circadia
Externí odkaz:
https://doaj.org/article/de55e1509f124a0abfb8302569ca6e67
Autor:
Darragh Duffy, Amina Dawoodji, Else Marie Agger, Peter Andersen, Jürgen Westermann, Eric B Bell
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8272 (2009)
BACKGROUND:High levels of death and morbidity worldwide caused by tuberculosis has stimulated efforts to develop a new vaccine to replace BCG. A number of Mycobacterium tuberculosis (Mtb)-specific antigens have been synthesised as recombinant subunit
Externí odkaz:
https://doaj.org/article/999c2268daf54b7c92c87060ea163276
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background The anatomy dissection course is a major part of the first two years of the traditional medical curriculum in Germany. The vast amount of content to be learned and the repeated examination is unanimously perceived by students and
Externí odkaz:
https://doaj.org/article/d83a5ad4eae34ec6927649fbe790dad2
Autor:
Darko Ciric, Jűrgen Westermann, Ivana M. Lalić, Sanja Despotović, Rene De Waal Malefyt, Novica M. Milićević, Živana Milićević
Publikováno v:
The Anatomical Record. 297:1472-1477
Metallophilic macrophages hold a strategic position within the thymic tissue and play a considerable function in thymic physiology. The development and positioning of these cells within thymic tissue are regulated by complex molecular mechanisms invo
Autor:
Novica M, Milićević, Ivana M, Lalić, Sanja Z, Despotović, Darko N, Ćirić, Jűrgen, Westermann, Rene, De Waal Malefyt, Živana, Milićević
Publikováno v:
Anatomical record (Hoboken, N.J. : 2007). 297(8)
Metallophilic macrophages hold a strategic position within the thymic tissue and play a considerable function in thymic physiology. The development and positioning of these cells within thymic tissue are regulated by complex molecular mechanisms invo