Zobrazeno 1 - 10
of 715
pro vyhledávání: '"Jürgen-C. Becker"'
Autor:
Lea Jessica Albrecht, Viktor Grünwald, Jürgen C. Becker, Ralf Gutzmer, Livia Asan, Ellen Uslar, Alexandra Eilers, Anne-Christine Müseler, Alexander Roesch, Dirk Schadendorf, Lisa Zimmer, Elisabeth Livingstone
Publikováno v:
EJC Skin Cancer, Vol 2, Iss , Pp 100261- (2024)
Introduction: Paraneoplastic hypercalcemia is a life-threatening complication and is usually caused by tumoral secretion of parathyroid hormone-related peptide (PTHrP). Endocrinopathies are common adverse events of immune checkpoint inhibitor (ICI) t
Externí odkaz:
https://doaj.org/article/8f76da47c470484490ffa38b95e0d931
Autor:
Nalini Srinivas, Lukas Peiffer, Kai Horny, Kuan Cheok Lei, Terkild B. Buus, Linda Kubat, Meng Luo, Menghong Yin, Ivelina Spassova, Antje Sucker, Farnoush Farahpour, Jan Kehrmann, Selma Ugurel, Elisabeth Livingstone, Thilo Gambichler, Niels Ødum, Jürgen C. Becker
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundMycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma (CTCL). Comprehensive analysis of MF cells in situ and ex vivo is complicated by the fact that is challenging to distinguish malignant from reactive T cells with
Externí odkaz:
https://doaj.org/article/b05b6c455d114b53a032805bb49cb832
Autor:
Nessr Abu Rached, Jürgen C. Becker, Anke S. Lonsdorf, Aric Keller, Ioannis A. Zeglis, Thilo Gambichler
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionMerkel cell carcinoma (MCC) is an aggressive skin cancer with a poor prognosis, which only improved with the introduction of immunotherapies. An MCC prediction model with high diagnostic accuracy is lacking. The aim was to develop an MCC
Externí odkaz:
https://doaj.org/article/e77184b7990e4465bd71e7f568683997
Autor:
Kai Horny, Christoph Sproll, Lukas Peiffer, Frauke Furtmann, Patricia Gerhardt, Jan Gravemeyer, Nikolas H. Stoecklein, Ivelina Spassova, Jürgen C. Becker
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/19906185e968466096b441b4c2f83991
Publikováno v:
Clinical Medicine Insights: Pathology, Vol 1 (2008)
Externí odkaz:
https://doaj.org/article/c0454cefde8e43d28127ce090eab6969
Autor:
Jan‐Malte Placke, Maximilian Zahn, Hannah Zillikens, Frederik Krefting, Georg C. Lodde, Lisa Zimmer, Elisabeth Livingstone, Eva Hadaschik, Antje Sucker, Alexander Roesch, Alpaslan Tasdogan, Nalini K. Srinivas, Dirk Schadendorf, Jürgen C. Becker, Selma Ugurel
Publikováno v:
JEADV Clinical Practice, Vol 2, Iss 4, Pp 810-818 (2023)
Abstract Background Merkel cell carcinoma (MCC) is one of the deadliest skin cancers. Despite existing national guidelines, treatment of MCC patients is not as well standardized as for more common skin cancers. Objectives The study objective was to i
Externí odkaz:
https://doaj.org/article/188049c65be2447ba65d4615d59cda63
Autor:
Kai Horny, Christoph Sproll, Lukas Peiffer, Frauke Furtmann, Patricia Gerhardt, Jan Gravemeyer, Nikolas H. Stoecklein, Ivelina Spassova, Jürgen C. Becker
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Oral squamous cell carcinoma (OSCC), an HPV-negative head and neck cancer, frequently metastasizes to the regional lymph nodes but only occasionally beyond. Initial phases of metastasis are associated with an epithelial–mesenchy
Externí odkaz:
https://doaj.org/article/c48f8fd3050046879760e0ef4332adfa
Autor:
Thilo Gambichler, David Schrama, Riina Käpynen, Sera S. Weyer-Fahlbusch, Jürgen C. Becker, Laura Susok, Florian Kreppel, Nessr Abu Rached
Publikováno v:
Vaccines, Vol 12, Iss 5, p 533 (2024)
Merkel cell carcinoma is a rare, aggressive skin cancer that mainly occurs in elderly and immunocompromised patients. Due to the success of immune checkpoint inhibition in MCC, the importance of immunotherapy and vaccines in MCC has increased in rece
Externí odkaz:
https://doaj.org/article/aca935283e7842faa73199b2bef58659
Autor:
Thilo Gambichler, Jonas Rüth, Silke Goesmann, Stefan Höxtermann, Marina Skrygan, Laura Susok, Jürgen C. Becker, Oliver Overheu, Wolfgang Schmidt, Anke Reinacher-Schick
Publikováno v:
Viruses, Vol 16, Iss 5, p 810 (2024)
In patients with COVID-19, broad panels of immune checkpoint molecules (ICPMs) and the purinergic signaling have not been studied in parallel. We aimed to perform in-depth immunophenotyping of major cell subsets present in human peripheral blood of C
Externí odkaz:
https://doaj.org/article/878c6a3945914e50a4b3dfc8f93469e1
Autor:
Jan-Malte Placke, Mona Kimmig, Klaus Griewank, Rudolf Herbst, Patrick Terheyden, Jochen Utikal, Claudia Pföhler, Jens Ulrich, Alexander Kreuter, Peter Mohr, Ralf Gutzmer, Friedegund Meier, Edgar Dippel, Julia Welzel, Daniel Robert Engel, Sophia Kreft, Antje Sucker, Georg Lodde, Frederik Krefting, Ingo Stoffels, Joachim Klode, Alexander Roesch, Lisa Zimmer, Elisabeth Livingstone, Eva Hadaschik, Jürgen C. Becker, Michael Weichenthal, Alpaslan Tasdogan, Dirk Schadendorf, Selma Ugurel
Publikováno v:
EBioMedicine, Vol 96, Iss , Pp 104774- (2023)
Summary: Background: PD-1-based immune checkpoint inhibition (ICI) is the major backbone of current melanoma therapy. Tumor PD-L1 expression represents one of few biomarkers predicting ICI therapy outcome. The objective of the present study was to sy
Externí odkaz:
https://doaj.org/article/2d744a8eed3741f3b79556e7478f0af0