Zobrazeno 1 - 10
of 502
pro vyhledávání: '"Jürgen Schrader"'
Autor:
Christian Jøns, Poul Erik Bloch Thomsen, Sam Riahi, Tom Smilde, Ulrich Bach, Peter Karl Jacobsen, Miloš Táborský, Jozsef Faluközy, Marcus Wiemer, Per Dahl Christensen, Attila Kónyi, Dan Schelfaut, Alan Bulava, Marcin Grabowski, Béla Merkely, Dieter Nuyens, Rajiv Mahajan, Patrick Nagel, Roland Tilz, Jerzy Malczynski, Clemens Steinwender, Johannes Brachmann, Harvey Serota, Jürgen Schrader, Steffen Behrens, Peter Søgaard
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
ObjectivesCardiac arrhythmias predict poor outcome after myocardial infarction (MI). We studied if arrhythmia monitoring with an insertable cardiac monitor (ICM) can improve treatment and outcome.DesignBIO|GUARD-MI was a randomized, international ope
Externí odkaz:
https://doaj.org/article/5cdccb0ebafe4e57b92767dd59e413d1
Autor:
Timo Massold, Fady Ibrahim, Viola Niemann, Bodo Steckel, Katrin Becker, Jürgen Schrader, Johannes Stegbauer, Sebastian Temme, Maria Grandoch, Ulrich Flögel, Pascal Bouvain
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Vascular inflammation plays a key role in the development of aortic diseases. A potential novel target for treatment might be CD73, an ecto-5′-nucleotidase that generates anti-inflammatory adenosine in the extracellular space. Here, we inv
Externí odkaz:
https://doaj.org/article/275be7bceaad46c48123f7ca0ed2f78a
Autor:
Giovanni Bisignani, Jim W. Cheung, Roberto Rordorf, Valentina Kutyifa, Daniel Hofer, Dana Berti, Luigi Di Biase, Eimo Martens, Vincenzo Russo, Paolo Vitillo, Marlies Zoutendijk, Thomas Deneke, Irina Köhler, Jürgen Schrader, Gaurav Upadhyay
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
IntroductionImplantable cardiac monitors (ICMs) provide long-term arrhythmia monitoring, but high rates of false detections increase the review burden. The new “SmartECG” algorithm filters false detections. Using large real-world data sets, we ai
Externí odkaz:
https://doaj.org/article/bd765e279ad249f283c607454bfe58c0
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113643- (2024)
Summary: CD73-derived adenosine suppresses anti-cancer immunity, and CD73 inhibitors are currently evaluated in several clinical trials. Here, we have assessed enzyme kinetics of all key purinergic ectoenzymes in five cancer cell lines (Hodgkin lymph
Externí odkaz:
https://doaj.org/article/5389bc7164e2488ab1d725d03ef6a2bc
Autor:
Dennis H. Lau, MBBS, PhD, FHRS, Bertrand Pierre, MD, Pilar Cabanas, MD, Eimo Martens, MD, Giovanni Bisignani, MD, Daniel Hofer, MD, Antonio Berruezo, MD, Romain Eschalier, MD, PhD, Jacques Mansourati, MD, Thomas Gaspar, MD, Victor Manuel Sanfins, MD, Andrejs Erglis, Andreas Hain, MD, Georgios Papaioannou, MD, Alessandro Cuneo, MD, Verena Tscholl, MD, Jürgen Schrader, PhD, Thomas Deneke, MD
Publikováno v:
Heart Rhythm O2, Vol 4, Iss 2, Pp 97-102 (2023)
Background: Insertable cardiac monitors (ICMs) are increasingly used for cardiac rhythm diagnosis with expanding indications. Little has been reported about their use and efficacy. Objective: The study sought to evaluate the clinical utility of a nov
Externí odkaz:
https://doaj.org/article/d85ce4317d4b43fabd68ed307084410c
Autor:
Angela Pelligra, Jessica Mrugala, Kerstin Griess, Philip Kirschner, Oliver Nortmann, Barbara Bartosinska, Andrea Köster, Natalia I. Krupenko, Dominik Gebel, Philipp Westhoff, Bodo Steckel, Daniel Eberhard, Diran Herebian, Bengt-Frederik Belgardt, Jürgen Schrader, Andreas P.M. Weber, Sergey A. Krupenko, Eckhard Lammert
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112703- (2023)
Externí odkaz:
https://doaj.org/article/e559785c47a14853b575dc202e1b53de
Autor:
Christina Alter, Anne-Sophie Henseler, Christoph Owenier, Julia Hesse, Zhaoping Ding, Tobias Lautwein, Jasmin Bahr, Sikander Hayat, Rafael Kramann, Eva Kostenis, Jürgen Scheller, Jürgen Schrader
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 11 (2023)
Plasma IL-6 is elevated after myocardial infarction (MI) and is associated with increased morbidity and mortality. Which cardiac cell type preferentially contributes to IL-6 expression and how its production is regulated are largely unknown. Here, we
Externí odkaz:
https://doaj.org/article/ba21c702fe434f01823d8dcc73bc160c
Autor:
Veronika Leiss, Roland P. Piekorz, Salvador Castaneda Vega, Christoph Jacoby, Ulrich Flögel, Katja Pexa, Jürgen Schrader, Bernd J. Pichler, Sandra Beer-Hammer, Bernd Nürnberg
Publikováno v:
Data in Brief, Vol 46, Iss , Pp 108851- (2023)
This article contains raw and processed data related to research published by Vega et al. (2022). This complementary dataset provides further insight into the experimental validation of a single common carotid artery occlusion (CCAO) model upon pretr
Externí odkaz:
https://doaj.org/article/6d52e522230f44f88f77be6845265ce5
Autor:
Ulrich Flögel, Sebastian Temme, Christoph Jacoby, Thomas Oerther, Petra Keul, Vera Flocke, Xiaowei Wang, Florian Bönner, Fabian Nienhaus, Karlheinz Peter, Jürgen Schrader, Maria Grandoch, Malte Kelm, Bodo Levkau
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The prediction of major cardiovascular events is still an unsolved problem. Here, the authors present a multi-color, multi-targeted non-invasive imaging technology that allows reliable in vivo identification of silent but prognostically highly releva
Externí odkaz:
https://doaj.org/article/63b7045c9fad435a95055854ca9ece41
Autor:
Andreas Kislat, Peter Olah, Marcus Kuchner, Peter Arne Gerber, Jürgen Schrader, Stephan Meller, Bernhard Homey
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9654 (2023)
Retinoids are a frequently used class of drugs in the treatment of inflammatory as well as malignant skin diseases. Retinoids have differential affinity for the retinoic acid receptor (RAR) and/or the retinoid X receptor (RXR). The endogenous dual RA
Externí odkaz:
https://doaj.org/article/5b7118b71e0a4eaa82b68253b150bd4d