Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jürgen Schloos"'
Autor:
Jürgen Schloos, Iris Treinies, Michael Paal, Veikko Koivisto, Achim Raap, Hans-Jürgen Mest, Ulrich Giese
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 364:47-52
Sulfonylureas stimulate insulin secretion independent of the blood glucose concentration. This can lead to hypoglycaemia in type 2 diabetic patients. Over the last years a number of imidazoline derivatives have been identified that stimulate insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257e5ce1a8fca867cb3f5ac6e9345c9a
https://doi.org/10.1007/s002100100415
https://doi.org/10.1007/s002100100415
Publikováno v:
British Journal of Pharmacology. 121:963-971
[125I]-[LTT]SRIF-28 and [125I]-SMS 201-995 were used to identify and characterize somatostatin (SRIF) receptors localized in rat lung tissue. In vitro autoradiography of rat lung tissue sections showed the existence of specific, high affinity binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32d52d91f3441d519abf84c7a9f8f3b8
https://doi.org/10.1038/sj.bjp.0701205
https://doi.org/10.1038/sj.bjp.0701205
Autor:
Friedrich Raulf, Daniel Hoyer, Gisbert Weckbecker, Hermann Lübbert, Christian Bruns, Jürgen Schloos
Publikováno v:
Scopus-Elsevier
In the past few years, five different somatostatin (SRIF) receptor subtypes (sst1.5) have been identified, which form a distinct group in the superfamily of G-protein-coupled receptors. The naturally occurring somatostatins SRIF-28, SRIF-25, and SRIF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6691701c6b3c0b7ffcb33f352118605
https://doi.org/10.1016/s0026-0495(96)90072-4
https://doi.org/10.1016/s0026-0495(96)90072-4
Autor:
Jürgen Schloos, Karin Weisser
Publikováno v:
Biochemical Pharmacology. 42:1729-1737
The relationship between serum angiotensin converting enzyme (ACE) activity and concentration of the ACE inhibitor enalaprilat was determined in vitro in the presence of different concentrations (S = 4-200 mM) of the substrate Hip-Gly-Gly. From Hende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb170aaee75cf8af5470ee4dec138e4
https://doi.org/10.1016/0006-2952(91)90509-4
https://doi.org/10.1016/0006-2952(91)90509-4
Publikováno v:
European Journal of Pharmacology. 196:247-255
The nature of the muscarinic receptor subtype mediating contraction of the endothelimn-denuded bovine coronary artery was investigated in vitro by functional measurements and radioligand binding studies. The acetylcholine (ACh)-induced isotonic contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93a5cfcc39f5190f92fb60315cd483c
https://doi.org/10.1016/0014-2999(91)90437-u
https://doi.org/10.1016/0014-2999(91)90437-u
Autor:
Achim Raap, Wolfgang Blechacz, Benjamin Armah, Jürgen Schloos, Hans-Jürgen Mest, Wolfgang Stenzel
Publikováno v:
Journal of cardiovascular pharmacology. 29(2)
The electromechanical and biochemical activities of the positive inotropic compounds BDF 9148 and DPI 201-106 were compared in guinea-pig myocardic preparations. Additionally, the properties of the BDF 9148 enantiomers were studied to compare their p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66783d30257246205e96d4685760907
https://pubmed.ncbi.nlm.nih.gov/9057064
https://pubmed.ncbi.nlm.nih.gov/9057064
Autor:
Jürgen Schloos, K. Breithaupt, Günter Neugebauer, Christian de Mey, Dieter Palm, Gustav G Belz
Publikováno v:
Clinical pharmacology and therapeutics. 55(3)
Objective To evaluate the pharmacodynamic properties of carvedilol across a broad range of doses in relation to its enantiospecific kinetics and adrenergic receptor occupancies, relative to placebo and propranolol. Methods Twelve healthy male subject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038177ee74b8e6c17eca62e538068d9e
https://pubmed.ncbi.nlm.nih.gov/7908256
https://pubmed.ncbi.nlm.nih.gov/7908256
Publikováno v:
Archiv der Pharmazie. 323(8)
The enantiospecific procedure for assaying carvedilol includes the extraction of the drug from plasma or urine with diisopropylether after alkalization of the sample with pH 9.8 buffer. After evaporation of the org. solvent a chiral derivatization is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55349463d077902915e5f0d63bab763
https://pubmed.ncbi.nlm.nih.gov/1980583
https://pubmed.ncbi.nlm.nih.gov/1980583