Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Jürgen Sühnel"'
Autor:
Rolf Hühne, Viktor Kessler, Axel Fürstberger, Silke Kühlwein, Matthias Platzer, Jürgen Sühnel, Ludwig Lausser, Hans A. Kestler
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-19 (2018)
Abstract Background The Ageing Factor Database AgeFactDB contains a large number of lifespan observations for ageing-related factors like genes, chemical compounds, and other factors such as dietary restriction in different organisms. These data prov
Externí odkaz:
https://doaj.org/article/b7d8828e5a7f4e1e9cf1c7185b557aac
Autor:
Peer Aramillo Irizar, Sascha Schäuble, Daniela Esser, Marco Groth, Christiane Frahm, Steffen Priebe, Mario Baumgart, Nils Hartmann, Shiva Marthandan, Uwe Menzel, Jule Müller, Silvio Schmidt, Volker Ast, Amke Caliebe, Rainer König, Michael Krawczak, Michael Ristow, Stefan Schuster, Alessandro Cellerino, Stephan Diekmann, Christoph Englert, Peter Hemmerich, Jürgen Sühnel, Reinhard Guthke, Otto W. Witte, Matthias Platzer, Eytan Ruppin, Christoph Kaleta
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Ageing is associated with a pronounced shift in mortality from cancer to degenerative diseases. Here, the authors show that in concordance with this shift, conserved transcriptional alterations during ageing across four vertebrates align with degener
Externí odkaz:
https://doaj.org/article/463f3bfceed14b74b71020ee1edcf215
Autor:
Peer Aramillo Irizar, Sascha Schäuble, Daniela Esser, Marco Groth, Christiane Frahm, Steffen Priebe, Mario Baumgart, Nils Hartmann, Shiva Marthandan, Uwe Menzel, Jule Müller, Silvio Schmidt, Volker Ast, Amke Caliebe, Rainer König, Michael Krawczak, Michael Ristow, Stefan Schuster, Alessandro Cellerino, Stephan Diekmann, Christoph Englert, Peter Hemmerich, Jürgen Sühnel, Reinhard Guthke, Otto W. Witte, Matthias Platzer, Eytan Ruppin, Christoph Kaleta
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in the spelling of the author Jule Müller, which was incorrectly given as Julia Müller. Additionally, in Fig. 4a, the blue-red colour scale for fold change in ageing/disease regulation include
Externí odkaz:
https://doaj.org/article/de3a5a1d161d427aa7fec4ef7bbcb4ed
Autor:
Jürgen Sühnel, Silke D. Kühlwein, Axel Fürstberger, Ludwig Lausser, Rolf Hühne, Matthias Platzer, Hans A. Kestler, Viktor Kessler
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-19 (2018)
BMC Bioinformatics
BMC bioinformatics, 19:390
BMC Bioinformatics
BMC bioinformatics, 19:390
Background The Ageing Factor Database AgeFactDB contains a large number of lifespan observations for ageing-related factors like genes, chemical compounds, and other factors such as dietary restriction in different organisms. These data provide quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f65adc546465b1410c7c67760e7324
http://link.springer.com/article/10.1186/s12859-018-2393-x
http://link.springer.com/article/10.1186/s12859-018-2393-x
Autor:
Julia J. Müller, Michael Ristow, Eytan Ruppin, Amke Caliebe, Steffen Priebe, Stefan Schuster, Shiva Marthandan, Alessandro Cellerino, Matthias Platzer, Peer Aramillo Irizar, Silvio Schmidt, Christoph Englert, Nils Hartmann, Rainer König, Jürgen Sühnel, Stephan Diekmann, Sascha Schäuble, Uwe Menzel, Michael Krawczak, Otto W. Witte, Peter Hemmerich, Marco Groth, Volker Ast, Reinhard Guthke, Christiane Frahm, Christoph Kaleta, Daniela Esser, Mario Baumgart
Publikováno v:
Nature Communications
Nature Communications, 9
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications, 9(1):327
Nature Communications, 9
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications, 9(1):327
Disease epidemiology during ageing shows a transition from cancer to degenerative chronic disorders as dominant contributors to mortality in the old. Nevertheless, it has remained unclear to what extent molecular signatures of ageing reflect this phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c116554ead2de81f7bdcc0dc50b1ee66
http://europepmc.org/articles/PMC5790807
http://europepmc.org/articles/PMC5790807
Autor:
Alessandro Cellerino, Sascha Schäuble, Nils Hartmann, Otto W. Witte, Christoph Kaleta, Daniela Esser, Peter Hemmerich, Stephan Diekmann, Eytan Ruppin, Stefan Schuster, Michael Ristow, Steffen Priebe, Matthias Platzer, Amke Caliebe, Volker Ast, Silvio Schmidt, Mario Baumgart, Michael Krawczak, Uwe Menzel, Marco Groth, Christoph Englert, Rainer König, Shiva Marthandan, Jürgen Sühnel, Peer Aramillo Irizar, Jule Müller, Reinhard Guthke, Christiane Frahm
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in the spelling of the author Jule Müller, which was incorrectly given as Julia Müller. Additionally, in Fig. 4a, the blue-red colour scale for fold change in ageing/disease regulation include
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bf649cbc906143cf8aa903ee28236e
https://doaj.org/article/de3a5a1d161d427aa7fec4ef7bbcb4ed
https://doaj.org/article/de3a5a1d161d427aa7fec4ef7bbcb4ed
Autor:
Jürgen Sühnel, James Adjaye, João Pedro de Magalhães, Anil Wipat, Günter Lepperdinger, Aubrey D.N.J. de Grey, Georg Fuellen
Publikováno v:
Rejuvenation Research. 13:763-767
Evidence is accumulating that the first genuine antiaging interventions (e.g., approved pharmaceutical, nutriceutical, and stem-cell-based therapies) will become available within the next decades. Model organism data, next-generation sequencing, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a8f1a96276297a33fd85ce5230cefd9
https://doi.org/10.1089/rej.2010.1125
https://doi.org/10.1089/rej.2010.1125
Autor:
Jürgen Sühnel, Klaus Gustav
Publikováno v:
Zeitschrift für Chemie. 20:283-293
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0dad0deec7ce9b897b09f902a452a17
https://doi.org/10.1002/zfch.19800200803
https://doi.org/10.1002/zfch.19800200803
Publikováno v:
Theoretical Chemistry Accounts. 125:217-231
Coarse-grained models are used to assess the packing of the 30-nm chromatin fiber. First, rigid assembly models for nucleosomal repeats from 155 to 211 bp are built using the crystal structure of the mononucleosome and attached straight stretches of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::418c946872f218b917b8c88660fdb37a
https://doi.org/10.1007/s00214-009-0561-9
https://doi.org/10.1007/s00214-009-0561-9
Publikováno v:
Nucleic Acids Research
DiProDB (http://diprodb.fli-leibniz.de) is a database of conformational and thermodynamic dinucleotide properties. It includes datasets both for DNA and RNA, as well as for single and double strands. The data have been shown to be important for under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb7ccb408df9d7f400fefe336a94b77
https://doi.org/10.1093/nar/gkn597
https://doi.org/10.1093/nar/gkn597