Zobrazeno 1 - 10
of 391
pro vyhledávání: '"Jürgen Peters"'
Autor:
Lars Palmowski, Simone Lindau, Laura Contreras Henk, Britta Marko, Andrea Witowski, Hartmuth Nowak, Sandra E. Stoll, Kai Zacharowski, Bernd W. Böttiger, Jürgen Peters, Michael Adamzik, Fabian Dusse, Tim Rahmel
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Background In sepsis, initial resuscitation with fluids is followed by efforts to achieve a negative fluid balance. However, patients with sepsis-associated acute kidney injury (SA-AKI) often need diuretic or renal replacement therapy (RRT).
Externí odkaz:
https://doaj.org/article/c85ae1f3476e42a0b3c9fa8d3dcca0b7
Publikováno v:
BMC Anesthesiology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Echocardiographic quantification of ejection fraction (EF) by manual endocardial tracing requires training, is time-consuming and potentially user-dependent, whereas determination of cardiac output by pulmonary artery catheterizat
Externí odkaz:
https://doaj.org/article/35dd23260714411aa617c7277463bb8d
Autor:
Willem Buys, Alexandra Bick, Rabea J. Madel, Astrid M. Westendorf, Jan Buer, Frank Herbstreit, Carsten J. Kirschning, Jürgen Peters
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionEarly sepsis is a life-threatening immune dysregulation believed to feature a “cytokine storm” due to activation of pattern recognition receptors by pathogen and danger associated molecular patterns. However, treatments with single to
Externí odkaz:
https://doaj.org/article/0f6bd744994d4ebcab332f1c92080099
Publikováno v:
BMC Anesthesiology, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background The mechanisms of trauma induced coagulopathy (TIC) are considered multifactorial. Amongst others, however, shedding of the endothelial glycocalyx resulting in increased concentrations of glycocalyx fragments in plasma might also
Externí odkaz:
https://doaj.org/article/d0ffc434683841a2a0978ee9711db820
Publikováno v:
BMC Anesthesiology, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Epigenetic modulation may play a role in anesthesia related phenotypes, such as cognitive impairment or memory loss, especially with exposure to anesthetics in the vulnerable phase of brain development. While isoflurane anesthesia
Externí odkaz:
https://doaj.org/article/2cb686c171264e6a9286172b19e0827f
Autor:
Linda E. Cox, Kai Walstein, Lena Völlger, Friederike Reuner, Alexandra Bick, Annika Dötsch, Andrea Engler, Jürgen Peters, Maren von Köckritz-Blickwede, Simon T. Schäfer
Publikováno v:
BMC Anesthesiology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background There is little knowledge, whether in patients with sepsis neutrophil extracellular trap (NET) formation and NET degrading nuclease activity are altered. Thus, we tested the hypotheses that 1) NET formation from neutrophils of sep
Externí odkaz:
https://doaj.org/article/a9e95e84342c4822aab23297fcb152e2
Autor:
Alexandra Bick, Willem Buys, Andrea Engler, Rabea Madel, Mazen Atia, Francesca Faro, Astrid M Westendorf, Andreas Limmer, Jan Buer, Frank Herbstreit, Carsten J Kirschning, Jürgen Peters
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0273247 (2022)
RationaleThe immune profile of sepsis patients is incompletely understood and hyperinflammation and hypoinflammation may occur concurrently or sequentially. Immune checkpoint inhibition (ICI) may counter hypoinflammation but effects are uncertain. We
Externí odkaz:
https://doaj.org/article/6ea8ff6976ca474f997f552712c7e3fe
Publikováno v:
BMC Anesthesiology, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Since inadequate heparin anticoagulation and insufficient reversal can result in complications during cardiopulmonary bypass (CPB) surgery, heparin anticoagulation monitoring by point-of-care (POC) activated clotting time (ACT) me
Externí odkaz:
https://doaj.org/article/812673038fa64e57ab0a991236085540
Autor:
Maike Stegen, Andrea Engler, Crista Ochsenfarth, Iris Manthey, Jürgen Peters, Winfried Siffert, Ulrich H Frey
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247087 (2021)
BackgroundG protein-coupled receptor kinase 6 (GRK6) is part of the G protein-coupled receptor kinase family, whose members act as key regulators of seven-transmembrane receptor signalling. GRK6 seems to play a role in regulation of inflammatory proc
Externí odkaz:
https://doaj.org/article/64594149fe924cbe83d8e5eb4c8c98be
Autor:
Tim Rahmel, Stefanie Schmitz, Hartmuth Nowak, Kaspar Schepanek, Lars Bergmann, Peter Halberstadt, Stefan Hörter, Jürgen Peters, Michael Adamzik
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228952 (2020)
Patients with severe infections and especially sepsis have a high in-hospital mortality, but even hospital survivors face long-term sequelae, decreased health-related quality of life, and high risk of death, suggesting a great need for specialized af
Externí odkaz:
https://doaj.org/article/29a98b3ef9154c2c84a59e20fa6f86d8