Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jürgen Okun"'
Autor:
Johannes Holle, Marietta Kirchner, Jürgen Okun, Aysun K Bayazit, Lukasz Obrycki, Nur Canpolat, Ipek Kaplan Bulut, Karolis Azukaitis, Ali Duzova, Bruno Ranchin, Rukshana Shroff, Cengiz Candan, Jun Oh, Günter Klaus, Francesca Lugani, Charlotte Gimpel, Rainer Büscher, Alev Yilmaz, Esra Baskin, Hakan Erdogan, Ariane Zaloszyc, Gül Özcelik, Dorota Drozdz, Augustina Jankauskiene, Francois Nobili, Anette Melk, Uwe Querfeld, Franz Schaefer, C Study Consortium
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240446 (2020)
The uremic toxins indoxyl sulfate (IS) and p-cresyl sulfate (pCS) accumulate in patients with chronic kidney disease (CKD) as a consequence of altered gut microbiota metabolism and a decline in renal excretion. Despite of solid experimental evidence
Externí odkaz:
https://doaj.org/article/21d901d7a05b44f09ca5807f9f9267aa
Autor:
Olaf Sommerburg, Susanne Hämmerling, S. Philipp Schneider, Jürgen Okun, Claus-Dieter Langhans, Patricia Leutz-Schmidt, Mark O. Wielpütz, Werner Siems, Simon Y. Gräber, Marcus A. Mall, Mirjam Stahl
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 483 (2021)
Rationale: Cystic fibrosis (CF), caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, leads to impaired pancreatic function and therefore reduced intestinal absorption of lipids and fat-soluble vitamins especial
Externí odkaz:
https://doaj.org/article/be35b711a4b64940872bfe40649354f3
Autor:
Alireza Saadatmand, Mark Pepin, Uwe Haberkorn, Jürgen Okun, Lisa Schlicker, Almut Schulze, Johannes Backs
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:189
Autor:
Christin, Riedinger, Michael, Mendler, Andrea, Schlotterer, Thomas, Fleming, Jürgen, Okun, Hans-Peter, Hammes, Stephan, Herzig, Peter P, Nawroth
Publikováno v:
The Journal of biological chemistry. 293(13)
The enzyme AICAR-transformylase/IMP cyclohydrolase (ATIC) catalyzes the last two steps of purine de novo synthesis. It metabolizes 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR), which is an AMP analogue, leading to activation of AMP-activated