Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jürgen Laufs"'
Autor:
Sabina Šturm, Klaus Weber, Primož Klinc, Ellinor Spörndly-Nees, Azadeh Fakhrzadeh, Tanja Knific, Andrej Škibin, Věra Fialová, Yoshimasa Okazaki, Tanja Razinger, Jürgen Laufs, Robert Kreutzer, Milan Pogačnik, Tanja Švara, Vesna Cerkvenik-Flajs
Publikováno v:
Toxics, Vol 10, Iss 5, p 224 (2022)
Bisphenol A (BPA), an endocrine-disrupting chemical and environmental pollutant, has been reported by many researchers to induce male reproductive toxicity in different experimental models. In this study, we investigated whether long-term exposure fo
Externí odkaz:
https://doaj.org/article/ceaf54fb99a4499db88b2a5d7b4d0bb5
Publikováno v:
International Journal of Vaccines & Vaccination. 4
Aluminum is currently the most commonly used vaccine adjuvant. Toxicity and safety in regards to the use of aluminum adjuvants is highly controversial and also confused by conflicting study results. In general, it is regarded as safe by the pharmaceu
Autor:
Bernhard Aigner, Matthias Klaften, Helmut Fuchs, Martin Hrabé de Angelis, Wolfgang Hans, Sibylle Sabrautzki, Jürgen Laufs, Reinhard Sedlmeier, Martina Klempt, Dian Michel, Mark D. Fleming, Birgit Rathkolb, Martina U. Muckenthaler, Marion Horsch, Eckhard Wolf, Dean R. Campagna
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 28(2)
Iron is essential for numerous cellular processes. For diagnostic purposes iron-related parameters in patients are assessed by clinical chemical blood analysis including the analysis of ferritin, transferrin and iron levels. Here, we retrospectively
Autor:
S. Seelig, M. Schöniger, S. Wattler, Thomas Peters, Martin Augustin, A. Koppius, E. Kochmann, Jürgen Laufs, C. Zinser, Reinhard Sedlmeier, M. Kilian, Michael Nehls, M. Voelkel, M. Klose, Ulrike Huffstadt, A. Wolf, D. Simon, M. Mayhaus, Dirk Korthaus, S. Franke, A. Graupner, Andreas Teubner, M. Kellner, M. Kurzmann, S. Garke-Mayerthaler
Publikováno v:
Mammalian Genome. 16:405-413
Mice with targeted genetic alterations are the most effective tools for deciphering organismal gene function. We generated an ENU-based parallel C3HeB/FeJ sperm and DNA archive characterized by a high probability to identify allelic variants of targe
Autor:
F. Heyraud-Nitschke, Bruno Gronenborn, Chantal David, S. Schumacher, Jürgen Laufs, Isabelle Jupin
Publikováno v:
Biochimie. 77:765-773
Replication of the single-stranded DNA genome of plant geminiviruses follows a rolling circle mechanism. It strictly depends on a 'replication initiator protein' (Rep) which is the sole viral protein essential for replication. Rep protein catalyzes m
Autor:
Eckhard Wolf, Reinhard Sedlmeier, Dian Michel, Bernhard Aigner, Matthias Klaften, Martina Klempt, Sibylle Wagner, Birgit Rathkolb, Jürgen Laufs, Boris Schneider, Martin Hrabé de Angelis
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 22(9-10)
Research on hematological disorders relies on suitable animal models. We retrospectively evaluated the use of the hematological parameters hematocrit (HCT), hemoglobin (HGB), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentratio
Autor:
Johannes Grosse, Wolfgang Jagla, S. Wattler, Boris Schneider, Andreas Schröder, Michael Nehls, Petra Hanke, Jürgen Laufs
Publikováno v:
Genes and immunity. 5(5)
Understanding the molecular regulation of immunoglobulin A (IgA) expression is important as it plays an essential role in the first-line defence through mucosal secretions. Using inbred mouse strains, we identified two independent and dominant acting
Autor:
Thorarinn Gislason, Eva Halapi, Hakon Hakonarson, Kari Stefansson, Jürgen Laufs, Emilia Soebech, Kristján Jónasson, Leifur Thorsteinsson, Andres Sigvaldason, Jeffrey R. Gulcher, Hjalti Andrason
Publikováno v:
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice. 4(1)
Background: Previous studies of vitamin D binding protein (VDBP, also known as group-specific component, Gc, encoded by the GC gene) have implicated two gene variants, GC*2 and GC*1F, as possible contributors with chronic obstructive pulmonary diseas
Autor:
Ulrich Heinzmann, Wolfgang Jagla, Rebecca A. Bergstrom, Gabriele Stumm, Andreas Marquardt, John C. Schimenti, Jürgen Laufs, Andreas Russ, Philipp Wabnitz, Francesca Pasutto, Rainer Paffenholz, David E. Bergstrom, Robert J. Munroe, Armin Bareiss
Publikováno v:
Genes Dev. 18, 1-6 (2004)
The vestibular system of the inner ear is responsible for the perception of motion and gravity. Key elements of this organ are otoconia, tiny biomineral particles in the utricle and the saccule. In response to gravity or linear acceleration, otoconia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dac945afd66f167ee30b199a2abc0d3
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=1753
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=1753
Autor:
Wolfgang Traut, Volker Matzeit, Francoise Heyraud, Bruno Gronenborn, Jeff Schell, Jürgen Laufs, Stephen G. Rogers
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 92(9)
Replication of the single-stranded DNA genome of geminiviruses occurs via a double-stranded intermediate that is subsequently used as a template for rolling-circle replication of the viral strand. Only one of the proteins encoded by the virus, here r