Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Jürgen J, Hubbuch"'
Publikováno v:
Biotechnology and bioengineering. 87(3)
This work presents the development, testing, and application in high-gradient magnetic fishing of superparamagnetic supports for adsorption of lectins. Various approaches were examined to produce affinity, mixed mode, and hydrophobic charge induction
Publikováno v:
Biotechnology and bioengineering. 87(3)
Expanded bed adsorption is an innovative chromatographic technology that allows the introduction of particle-containing feedstock without the risk of blocking the bed. Provided a perfectly classified fluidized bed (termed expanded bed) is formed in t
Publikováno v:
Biotechnology and bioengineering. 83(2)
Expanded bed adsorption is an integrated technology that allows the introduction of particle-containing feedstock without the risk of blocking the bed. The biomass particles contained in the feedstock have to be treated as an integral part of the pro
Publikováno v:
Biotechnology and bioengineering. 78(1)
A new fluid distribution system designed for expanded bed adsorption was introduced and studied in a 150-cm diameter column. Based on fluid application through a rotating distributor, it eradicates the need for perforated plates, meshes, or local mix
Autor:
Döring L; Process Science, Rentschler Biopharma SE, Erwin-Rentschler-Str. 21 88471 Laupheim, Germany; Karlsruhe Institute of Technology (KIT), Institute of Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Fritz-Haber-Weg 2 76131 Karlsruhe, Germany., Winderl J; Process Science, Rentschler Biopharma SE, Erwin-Rentschler-Str. 21 88471 Laupheim, Germany., Kron M; Process Science, Rentschler Biopharma SE, Erwin-Rentschler-Str. 21 88471 Laupheim, Germany., Hubbuch J; Karlsruhe Institute of Technology (KIT), Institute of Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Fritz-Haber-Weg 2 76131 Karlsruhe, Germany. Electronic address: juergen.hubbuch@kit.edu.
Publikováno v:
Journal of chromatography. A [J Chromatogr A] 2024 Oct 11; Vol. 1734, pp. 465261. Date of Electronic Publication: 2024 Aug 17.
Autor:
Valentic A; Institute of Process Engineering in Life Sciences - Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Hubbuch J; Institute of Process Engineering in Life Sciences - Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Publikováno v:
Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2024 Oct 03; Vol. 12, pp. 1475918. Date of Electronic Publication: 2024 Oct 03 (Print Publication: 2024).
Autor:
Beckert N; Institute of Process Engineering in Life Sciences-Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Germany., Dietrich A; Institute of Process Engineering in Life Sciences-Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Germany., Hubbuch J; Institute of Process Engineering in Life Sciences-Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Germany.
Publikováno v:
Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2024 Sep 16; Vol. 17 (9). Date of Electronic Publication: 2024 Sep 16.
Publikováno v:
Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2024 Sep 12; Vol. 32 (4), pp. 101335. Date of Electronic Publication: 2024 Sep 12 (Print Publication: 2024).
Autor:
Meutelet R; Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Bisch LJ; Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Buerfent BC; BioEcho Life Sciences GmbH, BioCampus Cologne, Köln, Germany., Müller M; BioEcho Life Sciences GmbH, BioCampus Cologne, Köln, Germany., Hubbuch J; Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Publikováno v:
Biotechnology journal [Biotechnol J] 2024 Sep; Vol. 19 (9), pp. e2400394.
Autor:
Weggen JT; Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Bean R; Purification Process Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, MD, United States., Hui K; Purification Process Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, MD, United States., Wendeler M; Purification Process Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, MD, United States., Hubbuch J; Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Publikováno v:
Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2024 Jul 11; Vol. 12, pp. 1403644. Date of Electronic Publication: 2024 Jul 11 (Print Publication: 2024).