Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jürgen Fichtl"'
Autor:
Felix Kuhne, Katrin Heinrich, Martin Winter, Jürgen Fichtl, Gabriel Hoffmann, Franziska Zähringer, Katharina Spitzauer, Monika Meier, Tarik A. Khan, Lea Bonnington, Katharina Wagner, Jan Olaf Stracke, Dietmar Reusch, Harald Wegele, Michael Mormann, Patrick Bulau
Publikováno v:
Analytical Chemistry. 95:2203-2212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::331b03c39357f6720c2a66af938caf48
https://doi.org/10.1021/acs.analchem.2c03099
https://doi.org/10.1021/acs.analchem.2c03099
Autor:
Jürgen Fichtl, Felix Kuhne, Rainer Lang, Harald Wegele, Patrick Bulau, Lea Bonnington, Dietmar Reusch, Markus Haberger, Anna-Katharina Heidenreich, Michaela Hook, Mahdi Adibzadeh, Florian Cymer
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32:2062-2071
The aim of this study was to characterize the product variants of a therapeutic T-cell bispecific humanized monoclonal antibody (TCB Mab, ∼200 kDa, asymmetric) and to develop an online cation-exchange chromatography native electrospray mass spectro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2933266ff4e346e4b66752323a0e13f
https://doi.org/10.1021/jasms.0c00446
https://doi.org/10.1021/jasms.0c00446
Autor:
Michael Adler, Katharina Diepold, Pierre Goldbach, Caroline Loew, Ulla Grauschopf, Hanns-Christian Mahler, Jürgen Fichtl, Constanze Knoblich, Nadja Alt, Patrick Bulau
Publikováno v:
Journal of pharmaceutical sciences. 101(11)
The presence of oxidized methionine residues in therapeutic monoclonal antibod- ies can potentially impact drug efficacy, safety, as well as antibody half-life in vivo. Therefore, methionine oxidation of antibodies is a strong focus during pharmaceut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d6cdf695c92eb1b3a50924d462ee63
https://pubmed.ncbi.nlm.nih.gov/22899501
https://pubmed.ncbi.nlm.nih.gov/22899501