Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial

Autor: Christoph Male, Anthonie W A Lensing, Joseph S Palumbo, Riten Kumar, Ildar Nurmeev, Kerry Hege, Damien Bonnet, Philip Connor, Hélène L Hooimeijer, Marcela Torres, Anthony K C Chan, Gili Kenet, Susanne Holzhauer, Amparo Santamaría, Pascal Amedro, Elizabeth Chalmers, Paolo Simioni, Rukhmi V Bhat, Donald L Yee, Olga Lvova, Jan Beyer-Westendorf, Tina T Biss, Ida Martinelli, Paola Saracco, Marjolein Peters, Krisztián Kállay, Cynthia A Gauger, M Patricia Massicotte, Guy Young, Akos F Pap, Madhurima Majumder, William T Smith, Jürgen F Heubach, Scott D Berkowitz, Kirstin Thelen, Dagmar Kubitza, Mark Crowther, Martin H Prins, Paul Monagle, Angelo C. Molinari, Ulrike Nowak Göttl, Juan Chain, Jeremy Robertson, Katharina Thom, Werner Streif, Rudolf Schwarz, Klaus Schmitt, Gernot Grangl, An Van Damme, Philip Maes, Veerle Labarque, Antonio Petrilli, Sandra Loggeto, Estela Azeka, Leonardo Brandao, Doan Le, Christine Sabapathy, Paola Giordano, Runhui Wu, Jie Ding, Wenyan Huang, Jianhua Mao, Päivi Lähteenmäki, Stephane Decramer, Toralf Bernig, Martin Chada, Godfrey Chan, Krisztian Kally, Beatrice Nolan, Shoshana Revel-Vilk, Hannah Tamary, Carina Levin, Daniela Tormene, Maria Abbattista, Andrea Artoni, Takanari Ikeyama, Ryo Inuzuka, Satoshi Yasukochi, Michelle Morales Soto, Karina A Solis Labastida, Monique H Suijker, Marike Bartels, Rienk Y Tamminga, C Heleen Van Ommen, D. Maroeska Te Loo, Rui Anjos, Lyudmila Zubarovskaya, Natalia Popova, Elena Samochatova, Margarita Belogurova, Pavel Svirin, Tatiana Shutova, Vladimir Lebedev, Olga Barbarash, Pei L Koh, Joyce C Mei, Ludmila Podracka, Ruben Berrueco, Maria F Fernandez, Tony Frisk, Sebastian Grunt, Johannes Rischewski, Manuela Albisetti-Pedroni, Ali Antmen, Huseyin Tokgoz, Zeynep Karakas, Jayashree Motwani, Michael Williams, John Grainger, Jeanette Payne, Mike Richards, Susan Baird, Neha Bhatnagar, Angela Aramburo, Shelley Crary, Tung Wynn, Shannon Carpenter, Sanjay Ahuja, Neil Goldenberg, Gary Woods, Kamar Godder, Ajovi Scott-Emuakpor, Gavin Roach, Leslie Raffini, Nirmish Shah, Sanjay Shah, Courtney Thornburg, Ayesha Zia, Roger Berkow

Publikováno v: Lancet Haematology, 7, e18-e27
Lancet Haematol.
The Lancet Haematology
Lancet Haematology, 7(1), E18-E27. ELSEVIER SCI LTD
The Lancet Haematology, Elsevier, 2019, ⟨10.1016/S2352-3026(19)30219-4⟩
Lancet. Haematology, 7(1), e18-e27. Lancet Publishing Group
LANCET HAEMATOL, Vol. 7, no.1, p. 18-27 (2020)
Lancet Haematology, 7, 1, pp. e18-e27
The Lancet Haematology, 7(1), E18-E27. ELSEVIER SCI LTD
The Lancet Haematology, Elsevier, 2019, 7 (1), ⟨10.1016/S2352-3026(19)30219-4⟩
Lancet Haematology
r-FISABIO. Repositorio Institucional de Producción Científica
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Contains fulltext : 219893.pdf (Publisher’s version ) (Closed access) BACKGROUND: Treatment of venous thromboembolism in children is based on data obtained in adults with little direct documentation of its efficacy and safety in children. The aim o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7274a4d6f1a8f89f43796a94d2a57da8

Design and Validation of a Bioreactor for Simulating the Cardiac Niche: A System Incorporating Cyclic Stretch, Electrical Stimulation, and Constant Perfusion

Autor: Liang Lu, Carsten Werner, Xuegeng Yang, Hans-Joachim Schnittler, Jürgen F. Heubach, Heinz-Felix Körber, Sönke Weinert, Ursula Ravens, Matthias Mende

Publikováno v: Tissue Engineering Part A. 19:403-414

To simulate the cardiac niche, a bioreactor system was designed and constructed to incorporate cyclic stretch, rhythmic electrical stimulation, and constant perfusion. The homogeneity of surface strain distribution across the cell culture substrate w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db3621ea50a0d5e7b6e1cc964a0531f0
https://doi.org/10.1089/ten.tea.2012.0135

Reduction of hERG potassium currents by hyperosmolar solutions

Autor: Rolf Beckmann, Christa Hegele-Hartung, Erich Wettwer, Fumie Yabuuchi, Jürgen F. Heubach

Publikováno v: European Journal of Pharmacology. 566:222-225

We investigated the effects of hyperosmolar solutions on human ether-a-go-go related gene (hERG) potassium currents in chinese hamster ovary (CHO) cells. The addition of d-mannitol to the external solution caused cell shrinkage and reduced current am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a06980f44277142097efe9d7e2dc91
https://doi.org/10.1016/j.ejphar.2007.03.028

Tissue distribution of a human Cav1.2 α1 subunit splice variant with a 75bp insertion☆

Autor: Wiltrud Richter, Ihor Zahanich, Sabine Boxberger, Jürgen F. Heubach, Eva M. Graf, Manja Bock, Jobst H. Schultz, Ursula Ravens

Publikováno v: Cell Calcium. 38:11-21

Mesenchymal stem cells from human bone marrow (MSC) express mRNA encoding the L-type Ca2+ channel Ca v 1.2 alpha1 subunit (alpha(1)1.2). We now describe a splice variant including an alternative exon of 75 bp in the region between exons 9 and 10, whi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17f0f24ac8b6e5bd4a8fe7c5cfc8a8e
https://doi.org/10.1016/j.ceca.2005.03.005

Electrophysiological properties of human mesenchymal stem cells

Autor: Ursula Ravens, Jürgen F. Heubach, Ihor Zahanich, Torsten Christ, Sabine Boxberger, Erich Wettwer, Bartosz Balana, Manja Bock, Eva M. Graf, Judith Leutheuser

Publikováno v: The Journal of Physiology. 554:659-672

Human mesenchymal stem cells (hMSC) have gained considerable interest due to their potential use for cell replacement therapy and tissue engineering. One strategy is to differentiate these bone marrow stem cells in vitro into cardiomyocytes prior to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::daf2c61a9599083d0be32c1a801247f0
https://doi.org/10.1113/jphysiol.2003.055806