Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jürgen Drossard"'
Autor:
Bart W Faber, Stephan Hellwig, Sophie Houard, Nicolas Havelange, Jürgen Drossard, Hubert Mertens, Alexander Croon, Robin Kastilan, Richard Byrne, Nicole van der Werff, Marjolein van der Eijk, Alan W Thomas, Clemens H M Kocken, Edmond J Remarque
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164053 (2016)
Plasmodium falciparum apical membrane antigen 1 (PfAMA1) is a leading asexual blood stage vaccine candidate for malaria. In preparation for clinical trials, three Diversity Covering (DiCo) PfAMA1 ectodomain proteins, designed to overcome the intrinsi
Externí odkaz:
https://doaj.org/article/46cb131ada9e43298252bc652224aff9
Publikováno v:
BioTechniques, Vol 23, Iss 6, Pp 996-1000 (1997)
Externí odkaz:
https://doaj.org/article/818f80ff9c9940a2bf00a9c9c191bb07
Publikováno v:
BIOspektrum. 20:464-466
The release of the pharmaceutical product Elelyso showed that plantderived biopharmaceuticals can compete economically with products from conventional expression systems. Improvements are required in terms of automation, consistency and purification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6beac00cb151e943ad1772daf05b5478
https://doi.org/10.1007/s12268-014-0464-8
https://doi.org/10.1007/s12268-014-0464-8
Publikováno v:
Biotechnology journal. 11(4)
The production of biopharmaceutical proteins in plants requires efficient downstream processing steps that remove impurities such as host cell proteins (HCPs) and adventitious endotoxins produced by bacteria during transient expression. We therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c010128f18fd3d131986744fb1d0f22
https://pubmed.ncbi.nlm.nih.gov/26632519
https://pubmed.ncbi.nlm.nih.gov/26632519
Autor:
Gabriela Stiegler, Brigitta Vcelar, Markus Sack, Thomas W. Rademacher, Valerie Isitt, Rainer Fischer, Craig J. van Dolleweerd, Julia Boyle, Philip J. Dale, Julian K.-C. Ma, Penelope Hundleby, Martin Lobedan, Hubert Mertens, Friedrich Altmann, Jürgen Drossard, Tom Cole, Mathew J. Paul, Eva Stoger, David J. M. Lewis, Richard M. Twyman, Paul Christou, Dietmar Katinger
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
instname
Although plant biotechnology has been widely investigated for the production of clinical-grade monoclonal antibodies, no antibody products derived from transgenic plants have yet been approved by pharmaceutical regulators for clinical testing. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba122f7ee842c246565d51d8f051995e
https://hdl.handle.net/10459.1/58877
https://hdl.handle.net/10459.1/58877
Autor:
Yolande Perrin, Duncan Keen, Esperanza Torres, Rainer Fischer, Liz Nicholson, Carmen Vaquero, Markus Sack, Sarah Williams, Jürgen Drossard, Paul Christou, Eva Stoger
Publikováno v:
Plant Molecular Biology. 42:583-590
This report describes the stable expression of a medically important antibody in the staple cereal crops rice and wheat. We successfully expressed a single-chain Fv antibody (ScFvT84.66) against carcinoembryonic antigen (CEA), a well characterized tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cc213bcafb58a806c3339b5fd1c98f9
https://doi.org/10.1023/a:1006301519427
https://doi.org/10.1023/a:1006301519427
Publikováno v:
Journal of Immunological Methods. 226:1-10
A TMV-specific full-size murine IgG-2b/kappa antibody (mAb24) was expressed in a Nicotiana tabacum cv. Petite Havana SR1 suspension culture (P9s), which was derived from a stably transformed transgenic plant (P9). The integration of an N-terminal mur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa5ec0503c6be901bc713f467780cdd
https://doi.org/10.1016/s0022-1759(99)00058-7
https://doi.org/10.1016/s0022-1759(99)00058-7
Autor:
Esperanza Torres, Carmen Vaquero, Liz Nicholson, Markus Sack, Eva Stöger, Jürgen Drossard, Paul Christou, Rainer Fischer, Yolande Perrin
Publikováno v:
Transgenic Research. 8:441-449
We investigated the suitability of transformed rice cell lines as a system for the production of therapeutic recombinant antibodies. Expression constructs encoding a single-chain Fv fragment (scFvT84.66, specific for CEA, the carcinoembryonic antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e38f1d2a59cea0dd6c7297075bbc6969
https://doi.org/10.1023/a:1008969031219
https://doi.org/10.1023/a:1008969031219
Publikováno v:
BioTechniques. 23:996-1000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a48733aa345bc3a6d34fda177de197c
https://doi.org/10.2144/97236bm05
https://doi.org/10.2144/97236bm05
Autor:
Alexander Croon, Clemens H. M. Kocken, Nicolas Havelange, Jürgen Drossard, Sophie Houard, Bart W. Faber, Robin Kastilan, Nicole van der Werff, Alan W. Thomas, Hubert Mertens, Marjolein van der Eijk, Richard W. Byrne, Edmond J. Remarque, Stephan Hellwig
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0164053 (2016)
PLoS ONE, Vol 11, Iss 10, p e0164053 (2016)
Plasmodium falciparum apical membrane antigen 1 (PfAMA1) is a leading asexual blood stage vaccine candidate for malaria. In preparation for clinical trials, three Diversity Covering (DiCo) PfAMA1 ectodomain proteins, designed to overcome the intrinsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959aad6f044cf097e722e90e6700adaf
https://doi.org/10.1371/journal.pone.0164053
https://doi.org/10.1371/journal.pone.0164053