Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jürgen Bockmann"'
Autor:
Berra Yildiz, Lisa Schiedt, Medhanie Mulaw, Jürgen Bockmann, Sarah Jesse, Anne-Kathrin Lutz, Tobias M. Boeckers
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Phelan-McDermid syndrome (PMS) is a syndromic form of Autism Spectrum Disorders (ASD) classified as a rare genetic neurodevelopmental disorder featuring global developmental delay, absent or delayed speech, ASD-like behaviour and neonatal skeletal mu
Externí odkaz:
https://doaj.org/article/82daea9de3a9404887a4b162e1af44a5
Autor:
Mubashir Ahmad, Nadine Stirmlinger, Irfana Jan, Ulrich Stifel, Sooyeon Lee, Marcel Weingandt, Ulrike Kelp, Jürgen Bockmann, Anita Ignatius, Tobias M. Böckers, Jan Tuckermann
Publikováno v:
JBMR Plus, Vol 7, Iss 2, Pp n/a-n/a (2023)
ABSTRACT Mutations of the postsynaptic scaffold protein Shank2 lead to autism spectrum disorders (ASD). These patients frequently suffer from higher fracture risk. Here, we investigated whether Shank2 directly regulates bone mass. We show that Shank2
Externí odkaz:
https://doaj.org/article/46146bcba9f2479d9d2e4235043799ce
Autor:
Helen Friedericke Bauer, Jan Philipp Delling, Jürgen Bockmann, Tobias M. Boeckers, Michael Schön
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2023)
Individuals with a SHANK3-related neurodevelopmental disorder, also termed Phelan-McDermid syndrome or abbreviated as PMS, exhibit significant global developmental delay, language impairment, and muscular hypotonia. Also common are repetitive behavio
Externí odkaz:
https://doaj.org/article/8a57b9e4971e4c57adacba32f68be7ee
Autor:
Katrin Studtmann, Janin Olschläger-Schütt, Friedrich Buck, Dietmar Richter, Carlo Sala, Jürgen Bockmann, Stefan Kindler, Hans-Jürgen Kreienkamp
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88518 (2014)
Local protein synthesis in dendrites enables neurons to selectively change the protein complement of individual postsynaptic sites. Though it is generally assumed that this mechanism requires tight translational control of dendritically transported m
Externí odkaz:
https://doaj.org/article/e2315c57f125443e98b496408024b1cb
Autor:
Mubashir Ahmad, Nadine Stirmlinger, Irfana Jan, Ulrich Stifel, Sooyeon Lee, Marcel Weingandt, Ulrike Kelp, Jürgen Bockmann, Anita Ignatius, Tobias M. Böckers, Jan Tuckermann
Publikováno v:
JBMR Plus. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76e1033e134a5e16353576399e684130
https://doi.org/10.1002/jbm4.10711
https://doi.org/10.1002/jbm4.10711
Publikováno v:
Journal of Neuroscience Methods. 181:227-234
Pre- and post-synaptic targeting of synaptic molecules is depending upon specific targeting signals that are encoded within defined regions of the respective protein. For the post-synaptic scaffolding proteins of excitatory synapses, ProSAP1/Shank2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3038588391adb3d1ddfe7ea887f18c86
https://doi.org/10.1016/j.jneumeth.2009.05.008
https://doi.org/10.1016/j.jneumeth.2009.05.008
Publikováno v:
Histochemistry and Cell Biology. 126:679-685
PSD95-DLG-ZO1 domain-containing proteins of the ProSAP/Shank family are major scaffolding proteins of the neuronal postsynaptic density which play a pivotal role in the linkage of membrane receptors to downstream signal effectors and the actin-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d95c7556173f2cd7c55453ebd39690b
https://doi.org/10.1007/s00418-006-0199-9
https://doi.org/10.1007/s00418-006-0199-9
Autor:
Thomas Dresbach, Jürgen Bockmann, Michael R. Kreutz, Eckart D. Gundelfinger, Thomas Liedtke, Tobias M. Boeckers, Christina Spilker
Publikováno v:
Journal of Neurochemistry. 92:519-524
Synapses are specialized contact sites mediating communication between neurons. Synaptogenesis requires the specific assembly of protein clusters at both sides of the synaptic contact by mechanisms that are barely understood. We studied the synaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b0c9d0412700c525c33f7f97fd128e
https://doi.org/10.1111/j.1471-4159.2004.02910.x
https://doi.org/10.1111/j.1471-4159.2004.02910.x
Autor:
Peter Iglauer, Tobias M. Böckers, Eckart D. Gundelfinger, Mailin Segger-Junius, Stefan Kindler, Michael R. Kreutz, Jürgen Bockmann, Dietmar Richter, Hans-Jürgen Kreienkamp
Publikováno v:
Molecular and Cellular Neuroscience. 26:182-190
Shank proteins are scaffolding proteins in the postsynaptic density of excitatory synapses in the mammalian brain. In situ hybridization revealed that Shank1/SSTRIP and Shank2/ProSAP1 mRNAs are widely expressed early in postnatal brain development wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c1b4a6862715351dccbf91003ab275
https://doi.org/10.1016/j.mcn.2004.01.009
https://doi.org/10.1016/j.mcn.2004.01.009
Autor:
Michael R. Kreutz, Eckart D. Gundelfinger, Jürgen Bockmann, Peter Redecker, Tobias M. Boeckers
Publikováno v:
Journal of Histochemistry & Cytochemistry. 51:809-819
Proteins of the presynaptic exocytic machinery have been found associated with the acrosome of male germ cells, suggesting that the sperm acrosome reaction and neurotransmission at chemical synapses may share some common mechanisms. To substantiate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55fbaf3af615e5689398b64636e24a63
https://doi.org/10.1177/002215540305100612
https://doi.org/10.1177/002215540305100612