Výsledky vyhledávání - "Jürgen Altherr"

Systemic and Hepatosplanchnic Hemodynamic and Metabolic Effects of the PARP Inhibitor PJ34 During Hyperdynamic Porcine Endotoxemia

Autor: Damian Vassilev, Marek Nalos, Peter Radermacher, Uwe B. Brückner, Gebhard Fröba, Csaba Szabó, Zsolt Iványi, Pierre Asfar, Antje Pittner, Jürgen Altherr, Balázs Hauser

Publikováno v: Shock. 19:415-421

Activation of the poly(ADP-ribose)polymerase (PARP), a highly energy-consuming DNA-repairing enzyme, plays a crucial role in the pathogenesis of multiorgan failure. Most results, however, were derived from experiments with hypodynamic shock states ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e499e313989ec3529a72f8666eddbd6
https://doi.org/10.1097/01.shk.0000048904.46342.22

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Hepatic oxygen exchange and energy metabolism in hyperdynamic porcine endotoxemia: effects of the combined thromboxane receptor antagonist and synthase inhibitor DTTX30

Autor: Peter Radermacher, Michael Georgieff, Carl Zülke, Arnim Vlatten, Ulrich Wachter, Uwe B. Brückner, K. W. Jauch, Martin Matejovic, Jürgen Altherr, Alexander Brinkmann, Josef Vogt, Karl Träger

Publikováno v: Intensive Care Medicine. 27:416-425

Objective: We compared the effects of thromboxane receptor antagonist and synthase inhibitor DTTX30 on systemic and liver blood flow, oxygen (O2) exchange and energy metabolism during 24 h of hyperdynamic endotoxemia with untreated endotoxemia. Desig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc60043031875a93e55c306f042680c
https://doi.org/10.1007/s001340000839

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Hepatic O2 exchange and liver energy metabolism in hyperdynamic porcine endotoxemia: effects of iloprost

Autor: Arnim Vlatten, Michael Georgieff, Martin Matejovic, Karl Träger, Alexander Brinkmann, Jürgen Altherr, Ulrich Wachter, K. W. Jauch, Peter Radermacher, Carl Zülke, Josef Vogt

Publikováno v: Intensive Care Medicine. 26:1531-1539

Objective: To compare the effects of a 12 h continuous infusion of iloprost, a stable prostacyclin analogue, on hepatic blood flow (Qliv), O2 exchange, and energy metabolism during a 24 h hyperdynamic, porcine endotoxemia with volume resuscitation al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047b1a82c720520eb62c2548b927588f
https://doi.org/10.1007/s001340000645

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Effects of the combined thromboxane receptor antagonist and synthase inhibitor DTTX-30 on intestinal O2-exchange and energy metabolism during hyperdynamic porcine endotoxemia

Autor: Martin Matejovic, Alexander Brinkmann, Uwe B. Brückner, Peter Radermacher, Carl Zülke, Karl Träger, Jürgen Altherr, Arnim Vlatten, Michael K. Georgieff, Karl-Walter Jauch

Publikováno v: Shock (Augusta, Ga.). 13(4)

Sepsis may lead to deranged thromboxane-prostacyclin ratio with consecutive organ dysfunction. Because of the suggested role of the gut in the pathogenesis of septic shock and multiple organ failure, we investigated the effects of the novel dual thro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7daa84fc53f3128361759fdfc00d3e
https://pubmed.ncbi.nlm.nih.gov/10774620

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EFFECTS OF THE PARP INHIBITOR PJ34 DURING PORCINE ENDOTOXEMIA

Autor: Peter Radermacher, Damian Vassilev, Uwe B. Brückner, Zsolt Iványi, Pierre Asfar, Marek Nalos, Balázs Hauser, Gebhard Fröba, Jürgen Altherr, Csaba Szabó, Antje Pittner

Publikováno v: Shock. 18:11

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ad95b0d6f0cfcae048f62e19fef57ec
https://doi.org/10.1097/00024382-200209001-00029

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