Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Jürgen Löffler"'
Autor:
Antje Häder, Sascha Schäuble, Jan Gehlen, Nadja Thielemann, Benedikt C. Buerfent, Vitalia Schüller, Timo Hess, Thomas Wolf, Julia Schröder, Michael Weber, Kerstin Hünniger, Jürgen Löffler, Slavena Vylkova, Gianni Panagiotou, Johannes Schumacher, Oliver Kurzai
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Innate immune responses vary by pathogen and host genetics. We analyze quantitative trait loci (eQTLs) and transcriptomes of monocytes from 215 individuals stimulated by fungal, Gram-negative or Gram-positive bacterial pathogens. We identify
Externí odkaz:
https://doaj.org/article/2cf885178e8843868db0af93d72f7768
Autor:
Maurice Hannemann, Dunja Wilmes, Frank Dombrowski, Jürgen Löffler, Alexander Kaminski, Astrid Hummel, Lena Ulm, Jürgen Bohnert, Volker Rickerts, Jan Springer, Holger N. Lode, Karoline Ehlert
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundInvasive mold infections are a well-known and life-threatening condition after allogeneic hematopoietic stem cell transplantation (HSCT). While Aspergillus species are recognized as predominant pathogens, Fusarium species should also be con
Externí odkaz:
https://doaj.org/article/243edd6f00f1449c8988bf9dc37631d2
Autor:
Nora Trinks, Sebastian Reinhard, Matthias Drobny, Linda Heilig, Jürgen Löffler, Markus Sauer, Ulrich Terpitz
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Trinks et al developed a protocol that enables super-resolved visualisation of the interaction between natural killer cells and Aspergillus fumigatus hyphae by expansion microscopy. They describe in detail steps of the formation of the immunological
Externí odkaz:
https://doaj.org/article/7edcd93f14fb4d519a1579614fdf2faa
Autor:
Beeke Tappe, Chris D. Lauruschkat, Lea Strobel, Jezreel Pantaleón García, Oliver Kurzai, Silke Rebhan, Sabrina Kraus, Elena Pfeuffer-Jovic, Lydia Bussemer, Lotte Possler, Matthias Held, Kerstin Hünniger, Olaf Kniemeyer, Sascha Schäuble, Axel A. Brakhage, Gianni Panagiotou, P. Lewis White, Hermann Einsele, Jürgen Löffler, Sebastian Wurster
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Patients suffering from coronavirus disease-2019 (COVID-19) are susceptible to deadly secondary fungal infections such as COVID-19-associated pulmonary aspergillosis and COVID-19-associated mucormycosis. Despite this clinical observation, direct expe
Externí odkaz:
https://doaj.org/article/d722827bb9fc46acb787b360a554ab51
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
All Aspergillus species form phialidic conidia (PC) when the mycelium is in contact with the air. These small, asexual spores are ideally suited for an airborne dissemination in the environment. Aspergillus terreus and a few closely related species f
Externí odkaz:
https://doaj.org/article/d8906a40bcf0489084d7b4a9af35d652
Autor:
P. Lewis White, Jan Springer, Matt P. Wise, Hermann Einsele, Claudia Löffler, Michelle Seif, Sabrina Prommersberger, Matthijs Backx, Jürgen Löffler
Publikováno v:
Journal of Fungi, Vol 8, Iss 1, p 81 (2022)
The COVID-19 pandemic has resulted in large numbers of patients requiring critical care management. With the established association between severe respiratory virus infection and invasive pulmonary aspergillosis (7.6% for COVID-19-associated pulmona
Externí odkaz:
https://doaj.org/article/efe845a2579c447080bbf98a4ec3a177
Autor:
João Pedro Saraiva, Marcus Oswald, Antje Biering, Daniela Röll, Cora Assmann, Tilman Klassert, Markus Blaess, Kristin Czakai, Ralf Claus, Jürgen Löffler, Hortense Slevogt, Rainer König
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background The human immune system is responsible for protecting the host from infection. However, in immunocompromised individuals the risk of infection increases substantially with possible drastic consequences. In extreme, systemic infect
Externí odkaz:
https://doaj.org/article/a93697315da642be969de5a5127e280f
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Infectious diseases are still a significant cause of morbidity and mortality worldwide. Despite the progress in drug development, the occurrence of microbial resistance is still a significant concern. Alternative therapeutic strategies are required f
Externí odkaz:
https://doaj.org/article/dccffadc9b0a4b74a943e7ea81563c1a
Autor:
Mugdha Srivastava, Elena Bencurova, Shishir K. Gupta, Esther Weiss, Jürgen Löffler, Thomas Dandekar
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Dendritic cells (DCs) are antigen presenting cells which serve as a passage between the innate and the acquired immunity. Aspergillosis is a major lethal condition in immunocompromised patients caused by the adaptable saprophytic fungus Aspergillus f
Externí odkaz:
https://doaj.org/article/b9f689c6e0c443829163876d75c802d4
Autor:
Vera Voltersen, Matthew G. Blango, Sahra Herrmann, Franziska Schmidt, Thorsten Heinekamp, Maria Strassburger, Thomas Krüger, Petra Bacher, Jasmin Lother, Esther Weiss, Kerstin Hünniger, Hong Liu, Peter Hortschansky, Alexander Scheffold, Jürgen Löffler, Sven Krappmann, Sandor Nietzsche, Oliver Kurzai, Hermann Einsele, Olaf Kniemeyer, Scott G. Filler, Utz Reichard, Axel A. Brakhage
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Aspergillus fumigatus is a common airborne fungal pathogen of humans and a significant source of mortality in immunocompromised individuals. Here, we provide the most extensive cell wall proteome profiling to date of A. fumigatus resting con
Externí odkaz:
https://doaj.org/article/9fe5a0ecbee347959685d1702c23f58a