Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Jürgen Graf"'
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110997- (2024)
Summary: Recent advances in understanding how neuronal activity shapes developing brain circuits increasingly rely on Gi/o-dependent inhibitory chemogenetic tools (Gi-DREADDs). However, their mechanisms of action and efficacy in neurons with immature
Externí odkaz:
https://doaj.org/article/fbedcfadcefb4d94bb92f62bc8f006e7
Autor:
Simon Weiler, Vahid Rahmati, Marcel Isstas, Johann Wutke, Andreas Walter Stark, Christian Franke, Jürgen Graf, Christian Geis, Otto W. Witte, Mark Hübener, Jürgen Bolz, Troy W. Margrie, Knut Holthoff, Manuel Teichert
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Tactile sensation and vision are often both utilized for the exploration of objects that are within reach though it is not known whether or how these two distinct sensory systems combine such information. Here in mice, we used a combination
Externí odkaz:
https://doaj.org/article/89b253e6788f4c7bad847a600e743e75
Autor:
Uwe Stüben, Jürgen Graf
Die Notfallversorgung an Bord eines Linienflugzeuges ist eine besondere Herausforderung. Trotz der Einschränkungen an Bord ermöglicht die Notfallausrüstung professionelles Handeln. Außerdem ist der Arzt oft als Berater in die Entscheidung über W
Network instability dynamics drive a transient bursting period in the developing hippocampus in vivo
Autor:
Jürgen Graf, Vahid Rahmati, Myrtill Majoros, Otto W Witte, Christian Geis, Stefan J Kiebel, Knut Holthoff, Knut Kirmse
Publikováno v:
eLife, Vol 11 (2022)
Spontaneous correlated activity is a universal hallmark of immature neural circuits. However, the cellular dynamics and intrinsic mechanisms underlying network burstiness in the intact developing brain are largely unknown. Here, we use two-photon Ca2
Externí odkaz:
https://doaj.org/article/5a64059fe9df40bb9387c360249f5778
Autor:
Karolina Benesova, Franziska Viktoria Kraus, Rui A Carvalho, Holger Lorenz, Christian H Hörth, Janine Günther, Karel D Klika, Jürgen Graf, Leonore Diekmann, Timo Schank, Petros Christopoulos, Jessica C Hassel, Hanns-Martin Lorenz, Margarida Souto-Carneiro
Publikováno v:
Annals of the Rheumatic Diseases. 81:1730-1741
ObjectivesRheumatic immune-related adverse events (irAE) such as (poly)arthritis in patients undergoing immune checkpoint inhibitor (ICI) treatment pose a major clinical challenge. ICI therapy improves CD8+T cell (CD8) function, but CD8 contributes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d68854b267c6722c357c4023db46573
https://doi.org/10.1136/ard-2022-222451
https://doi.org/10.1136/ard-2022-222451
Autor:
Kyra Schneider, Jürgen Graf
Publikováno v:
Handbuch IQM. Konsequent transparent – Qualität mit Routinedaten! 3. Auflage ISBN: 9783954668106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63be9f676619165e5e16cddf9f3e0593
https://doi.org/10.32745/9783954668106-16
https://doi.org/10.32745/9783954668106-16
Publikováno v:
Bautechnik. 99:76-84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eb55233bb5df13d28ba7f01fe28c766
https://doi.org/10.1002/bate.202100111
https://doi.org/10.1002/bate.202100111
Publikováno v:
Bautechnik. 99:2-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e54f7aa7ee4a4f7d33f73bc356710cc2
https://doi.org/10.1002/bate.202100105
https://doi.org/10.1002/bate.202100105
Autor:
Franziska V. Kraus, Simon Keck, Karel D. Klika, Jürgen Graf, Rui A. Carvalho, Hanns‐Martin Lorenz, M. Margarida Souto‐Carneiro
ObjectivesRA CD8+ T-cells (CD8) maintain their effector pro-inflammatory phenotype by changing their metabolism towards aerobic glycolysis. However, their massive energetic and biosynthetic needs may require additional substrates to furnish this high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1eac6ed97246e01687b9f560bb9e45f
https://doi.org/10.1101/2022.09.22.22280236
https://doi.org/10.1101/2022.09.22.22280236