Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Jürgen, Steinhoff"'
Autor:
Philipp S. Orekhov, Marine E. Bozdaganyan, Natalia Voskoboynikova, Armen Y. Mulkidjanian, Maria G. Karlova, Anna Yudenko, Alina Remeeva, Yury L. Ryzhykau, Ivan Gushchin, Valentin I. Gordeliy, Olga S. Sokolova, Heinz-Jürgen Steinhoff, Mikhail P. Kirpichnikov, Konstantin V. Shaitan
Publikováno v:
Nanomaterials, Vol 12, Iss 3, p 361 (2022)
Amphiphilic copolymers consisting of alternating hydrophilic and hydrophobic units account for a major recent methodical breakthrough in the investigations of membrane proteins. Styrene–maleic acid (SMA), diisobutylene–maleic acid (DIBMA), and re
Externí odkaz:
https://doaj.org/article/a167d1deab034ef9be66ba5862c0bb35
Autor:
Maria Karlova, Natalia Voskoboynikova, Armen Y. Mulkidjanian, Konstantin V. Shaitan, Heinz-Jürgen Steinhoff, Jürgen J. Heinisch, Olga S. Sokolova
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 16-16 (2021)
Background: Wsc1 is the best studied of the five mechanosensors of the cell wall integrity (CWI) signal transduction pathway in Saccharomyces cerevisiae. In genetic and biophysical studies, Wsc1 functions were assessed either in living yeast cells or
Externí odkaz:
https://doaj.org/article/574ec6b5a0564d10a0bb8839356139a7
Autor:
Natalia Voskoboynikova, Maria Karlova, Rainer Kurre, Armen Y. Mulkidjanian, Konstantin V. Shaitan, Olga S. Sokolova, Heinz-Jürgen Steinhoff, Jürgen J. Heinisch
Publikováno v:
Journal of Fungi, Vol 7, Iss 2, p 118 (2021)
The cell wall sensor Wsc1 belongs to a small family of transmembrane proteins, which are crucial to sustain cell integrity in yeast and other fungi. Wsc1 acts as a mechanosensor of the cell wall integrity (CWI) signal transduction pathway which respo
Externí odkaz:
https://doaj.org/article/db6e338c1a314ca1ac9d56e2d30bd94b
Autor:
Nikolay Isaev, Heinz-Jürgen Steinhoff
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 169:44-51
Lyophilization can extend protein drugs stability and shelf life, but it also can lead to protein degradation in some cases. The development of safe freeze-drying approaches for sensitive proteins requires a better understanding of lyophilization on
Autor:
Marina Diskowski, Ahmad Reza Mehdipour, Dorith Wunnicke, Deryck J Mills, Vedrana Mikusevic, Natalie Bärland, Jan Hoffmann, Nina Morgner, Heinz-Jürgen Steinhoff, Gerhard Hummer, Janet Vonck, Inga Hänelt
Publikováno v:
eLife, Vol 6 (2017)
Ion channel gating is essential for cellular homeostasis and is tightly controlled. In some eukaryotic and most bacterial ligand-gated K+ channels, RCK domains regulate ion fluxes. Until now, a single regulatory mechanism has been proposed for all RC
Externí odkaz:
https://doaj.org/article/0e2d349b01314a5c922542b0a36d1ddd
Autor:
Philipp S Orekhov, Daniel Klose, Armen Y Mulkidjanian, Konstantin V Shaitan, Martin Engelhard, Johann P Klare, Heinz-Jürgen Steinhoff
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004561 (2015)
Motile bacteria and archaea respond to chemical and physical stimuli seeking optimal conditions for survival. To this end transmembrane chemo- and photoreceptors organized in large arrays initiate signaling cascades and ultimately regulate the rotati
Externí odkaz:
https://doaj.org/article/0ee02973b80846c9887aad445e5233e9
Autor:
Heiko Warnecke, Bernd Ettmer, Klaus-Jürgen Steinhoff, Linda Bromberg, Stefan Orlik, Clemens Löbnitz, Volker Thiele
Publikováno v:
WASSERWIRTSCHAFT. 109:72-76
Autor:
Natalia Voskoboynikova, Marine E. Bozdaganyan, Dmitry A. Cherepanov, Heinz-Jürgen Steinhoff, Konstantin V. Shaitan, Armen Y. Mulkidjanian, Alexey V. Lokhmatikov
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1860:439-451
Up to half of the cellular energy gets lost owing to membrane proton leakage. The permeability of lipid bilayers to protons is by several orders of magnitude higher than to other cations, which implies efficient proton-specific passages. The nature o
Autor:
Johanna Heuveling, Erwin Schneider, Nikolay Isaev, Heinz-Jürgen Steinhoff, Nikita V. Ivanisenko
Publikováno v:
Applied Magnetic Resonance. 50:883-893
Localization of substrates in membrane proteins is an important but challenging task. In this paper, we show that deuterium electron spin echo envelope modulation spectroscopy (2H ESEEM) combined with site-directed spin labeling is a powerful tool to
Autor:
Marine E. Bozdaganyan, Heinz-Jürgen Steinhoff, Philipp S. Orekhov, Armen Y. Mulkidjanian, Natalia Voskoboynikova, Konstantin V. Shaitan
Publikováno v:
Langmuir. 35:3748-3758
Amphiphilic copolymers composed of styrene and maleic acid (SMA) monomers caused a major methodical breakthrough in the study of membrane proteins. They were found to directly release phospholipids and membrane proteins both from artificial and natur