Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Jürgen, Geisler"'
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 1131-1139 (2024)
Introduction: This report presents a case of an exceptionally delayed distant recurrence of a choroidal melanoma, occurring 4 decades after the enucleation of the affected eye. Case Presentation: In 1977, a 29-year-old man underwent enucleation for a
Externí odkaz:
https://doaj.org/article/a19dd4cddc9242a29fbb4699b7a40503
Autor:
Lilly Anne Torland, Xiaoran Lai, Surendra Kumar, Margit H. Riis, Jürgen Geisler, Torben Lüders, Xavier Tekpli, Vessela Kristensen, Kristine Sahlberg, Andliena Tahiri
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2495-2509 (2024)
Benign breast tumors are a nonthreatening condition defined as abnormal cell growth within the breast without the ability to invade nearby tissue. However, benign lesions hold valuable biological information that can lead us toward better understandi
Externí odkaz:
https://doaj.org/article/5ea483944dc84bf1be52ac364dcb6ec1
Autor:
Wanja Kildal, Karolina Cyll, Joakim Kalsnes, Rakibul Islam, Frida M. Julbø, Manohar Pradhan, Elin Ersvær, Neil Shepherd, Ljiljana Vlatkovic, Xavier Tekpli, Øystein Garred, Gunnar B. Kristensen, Hanne A. Askautrud, Tarjei S. Hveem, Håvard E. Danielsen, Tone F. Bathen, Elin Borgen, Anne-Lise Børresen-Dale, Olav Engebråten, Britt Fritzman, Olaf Johan Hartman-Johnsen, Jürgen Geisler, Gry Aarum Geitvik, Solveig Hofvind, Rolf Kåresen, Anita Langerød, Ole Christian Lingjærde, Gunhild M. Mælandsmo, Bjørn Naume, Hege G. Russnes, Kristine Kleivi Sahlberg, Torill Sauer, Helle Kristine Skjerven, Ellen Schlichting, Therese Sørlie
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e32529- (2024)
We aimed to develop deep learning (DL) models to detect protein expression in immunohistochemically (IHC) stained tissue-sections, and to compare their accuracy and performance with manually scored clinically relevant proteins in common cancer types.
Externí odkaz:
https://doaj.org/article/e0dc5fe8cfec49769db7555ff4402d86
Autor:
Peeter Karihtala, Aglaia Schiza, Elena Fountzilas, Jürgen Geisler, Icro Meattini, Emanuela Risi, Laura Biganzoli, Antonios Valachis
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background and purpose: While the prevalence of older breast cancer patients is rapidly increasing, these patients are greatly underrepresented in clinical trials. We discuss barriers to recruitment of older patients to clinical trials and propose so
Externí odkaz:
https://doaj.org/article/7054a51862ab46378ff84b1e60247062
Autor:
Hossein Schandiz, Lorant Farkas, Daehoon Park, Yan Liu, Solveig N. Andersen, Jürgen Geisler, Torill Sauer
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveIn this study, we investigated pivotal molecular markers in human high-grade breast ductal carcinoma in situ (DCIS). Expression status of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth receptor 2 (HER2) was me
Externí odkaz:
https://doaj.org/article/68a9bbba82f248bdb919fb90e5aafe0a
Autor:
Feng Wang, Eline Eikeland, Randi J. Reidunsdatter, Lars Hagen, Monica J. Engstrøm, Jürgen Geisler, Mikko Haanpää, Esa Hämäläinen, Guro F. Giskeødegård, Tone F. Bathen
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionSystemic and local steroid hormone levels may function as novel prognostic and predictive biomarkers in breast cancer patients. We aimed at developing a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the simult
Externí odkaz:
https://doaj.org/article/305a8c0db112429886fe7c585347b0bb
Autor:
Oleksii Nikolaienko, Hans P. Eikesdal, Elisabet Ognedal, Bjørnar Gilje, Steinar Lundgren, Egil S. Blix, Helge Espelid, Jürgen Geisler, Stephanie Geisler, Emiel A. M. Janssen, Synnøve Yndestad, Laura Minsaas, Beryl Leirvaag, Reidun Lillestøl, Stian Knappskog, Per E. Lønning
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Normal cell BRCA1 epimutations have been associated with increased risk of triple-negative breast cancer (TNBC). However, the fraction of TNBCs that may have BRCA1 epimutations as their underlying cause is unknown. Neither are the
Externí odkaz:
https://doaj.org/article/0089602380aa46b390f13cb9bbdb281f
Autor:
Andreas Venizelos, Christina Engebrethsen, Wei Deng, Jürgen Geisler, Stephanie Geisler, Gjertrud T. Iversen, Turid Aas, Hildegunn S. Aase, Manouchehr Seyedzadeh, Eli Sihn Steinskog, Ola Myklebost, Sigve Nakken, Daniel Vodak, Eivind Hovig, Leonardo A. Meza-Zepeda, Per E. Lønning, Stian Knappskog, Hans P. Eikesdal
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-18 (2022)
Abstract Background Subclonal evolution during primary breast cancer treatment is largely unexplored. We aimed to assess the dynamic changes in subclonal composition of treatment-naïve breast cancers during neoadjuvant chemotherapy. Methods We perfo
Externí odkaz:
https://doaj.org/article/c8fdf6f22c9d4f50b2aecdfe0b4e304f
Autor:
Joana Reis, Joao Boavida, Hang T. Tran, Marianne Lyngra, Laurens Cornelus Reitsma, Hossein Schandiz, Woldegabriel A. Melles, Kjell-Inge Gjesdal, Jürgen Geisler, Jonn Terje Geitung
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Axillary lymph node (LN) metastasis is one of the most important predictors of recurrence and survival in breast cancer, and accurate assessment of LN involvement is crucial. Determining extent of residual disease is key for surgi
Externí odkaz:
https://doaj.org/article/118f66bf8e764c4d958dede358ab4be8
Autor:
Maria Escala-Garcia, Sander Canisius, Renske Keeman, Jonathan Beesley, Hoda Anton-Culver, Volker Arndt, Annelie Augustinsson, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Marina Bermisheva, Stig E. Bojesen, Manjeet K. Bolla, Hermann Brenner, Federico Canzian, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Fergus J. Couch, Kamila Czene, Mary B. Daly, Joe Dennis, Peter Devilee, Thilo Dörk, Alison M. Dunning, Douglas F. Easton, Arif B. Ekici, A. Heather Eliassen, Peter A. Fasching, Henrik Flyger, Manuela Gago-Dominguez, Montserrat García-Closas, José A. García-Sáenz, Jürgen Geisler, Graham G. Giles, Mervi Grip, Melanie Gündert, Eric Hahnen, Christopher A. Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Jaana M. Hartikainen, Bernadette A. M. Heemskerk-Gerritsen, Antoinette Hollestelle, Reiner Hoppe, John L. Hopper, David J. Hunter, William Jacot, Anna Jakubowska, Esther M. John, Audrey Y. Jung, Rudolf Kaaks, Elza Khusnutdinova, Linetta B. Koppert, Peter Kraft, Vessela N. Kristensen, Allison W. Kurian, Diether Lambrechts, Loic Le Marchand, Annika Lindblom, Robert N. Luben, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Dimitrios Mavroudis, Taru A. Muranen, Heli Nevanlinna, Andrew F. Olshan, Håkan Olsson, Tjoung-Won Park-Simon, Alpa V. Patel, Paolo Peterlongo, Paul D. P. Pharoah, Kevin Punie, Paolo Radice, Gad Rennert, Hedy S. Rennert, Atocha Romero, Rebecca Roylance, Thomas Rüdiger, Matthias Ruebner, Emmanouil Saloustros, Elinor J. Sawyer, Rita K. Schmutzler, Minouk J. Schoemaker, Christopher Scott, Melissa C. Southey, Harald Surowy, Anthony J. Swerdlow, Rulla M. Tamimi, Lauren R. Teras, Emilie Thomas, Ian Tomlinson, Melissa A. Troester, Celine M. Vachon, Qin Wang, Robert Winqvist, Alicja Wolk, Argyrios Ziogas, kConFab/AOCS Investigators, Kyriaki Michailidou, Georgia Chenevix-Trench, Thomas Bachelot, Marjanka K. Schmidt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Breast cancer metastasis accounts for most of the deaths from breast cancer. Identification of germline variants associated with survival in aggressive types of breast cancer may inform understanding of breast cancer progression and assist t
Externí odkaz:
https://doaj.org/article/15d48d4f4e3145c29057f7c26462140f