Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jürgen, Eils"'
Autor:
Kim K. Sommer, Ali Amr, Udo Bavendiek, Felix Beierle, Peter Brunecker, Henning Dathe, Jürgen Eils, Maximilian Ertl, Georg Fette, Matthias Gietzelt, Bettina Heidecker, Kristian Hellenkamp, Peter Heuschmann, Jennifer D. E. Hoos, Tibor Kesztyüs, Fabian Kerwagen, Aljoscha Kindermann, Dagmar Krefting, Ulf Landmesser, Michael Marschollek, Benjamin Meder, Angela Merzweiler, Fabian Prasser, Rüdiger Pryss, Jendrik Richter, Philipp Schneider, Stefan Störk, Christoph Dieterich
Publikováno v:
Life, Vol 12, Iss 5, p 749 (2022)
Risk prediction in patients with heart failure (HF) is essential to improve the tailoring of preventive, diagnostic, and therapeutic strategies for the individual patient, and effectively use health care resources. Risk scores derived from controlled
Externí odkaz:
https://doaj.org/article/2af5f865521a43caa7101f243f4d83ae
Autor:
Naveed Ishaque, Mohammed L. Abba, Christine Hauser, Nitin Patil, Nagarajan Paramasivam, Daniel Huebschmann, Jörg Hendrik Leupold, Gnana Prakash Balasubramanian, Kortine Kleinheinz, Umut H. Toprak, Barbara Hutter, Axel Benner, Anna Shavinskaya, Chan Zhou, Zuguang Gu, Jules Kerssemakers, Alexander Marx, Marcin Moniuszko, Miroslaw Kozlowski, Joanna Reszec, Jacek Niklinski, Jürgen Eils, Matthias Schlesner, Roland Eils, Benedikt Brors, Heike Allgayer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The evolution and genetic nature of metastatic lesions is not completely characterized. Here the authors perform a comprehensive whole-genome study of colorectal metastases in comparison to matched primary tumors and define a multistage progression m
Externí odkaz:
https://doaj.org/article/4e68117793d04d9682b7c9652d4393b8
Autor:
Fatemeh Behjati Ardakani, Kathrin Kattler, Karl Nordström, Nina Gasparoni, Gilles Gasparoni, Sarah Fuchs, Anupam Sinha, Matthias Barann, Peter Ebert, Jonas Fischer, Barbara Hutter, Gideon Zipprich, Charles D. Imbusch, Bärbel Felder, Jürgen Eils, Benedikt Brors, Thomas Lengauer, Thomas Manke, Philip Rosenstiel, Jörn Walter, Marcel H. Schulz
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-14 (2018)
Abstract Background Bidirectional promoters (BPs) are prevalent in eukaryotic genomes. However, it is poorly understood how the cell integrates different epigenomic information, such as transcription factor (TF) binding and chromatin marks, to drive
Externí odkaz:
https://doaj.org/article/aeda19e919924fcba37b9cf5784814fb
Autor:
Hans-Ulrich, Prokosch, Thomas, Bahls, Martin, Bialke, Jürgen, Eils, Christian, Fegeler, Julian, Gruendner, Birger, Haarbrandt, Christopher, Hampf, Wolfgang, Hoffmann, Hauke, Hund, Marvin, Kampf, Lorenz A, Kapsner, Piotr, Kasprzak, Oliver, Kohlbacher, Dagmar, Krefting, Jonathan M, Mang, Michael, Marschollek, Sebastian, Mate, Armin, Müller, Fabian, Prasser, Julian, Sass, Sebastian, Semler, Holger, Stenzhorn, Sylvia, Thun, Sven, Zenker, Roland, Eils
Publikováno v:
Studies in health technology and informatics. 294
COVID-19 has challenged the healthcare systems worldwide. To quickly identify successful diagnostic and therapeutic approaches large data sharing approaches are inevitable. Though organizational clinical data are abundant, many of them are available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ccfeaaf304850bfc78d35ee28cd61e7
https://pubmed.ncbi.nlm.nih.gov/35612174
https://pubmed.ncbi.nlm.nih.gov/35612174
Autor:
Hans-Ulrich Prokosch, Thomas Bahls, Martin Bialke, Jürgen Eils, Christian Fegeler, Julian Gruendner, Birger Haarbrandt, Christopher Hampf, Wolfgang Hoffmann, Hauke Hund, Marvin Kampf, Lorenz A. Kapsner, Piotr Kasprzak, Oliver Kohlbacher, Dagmar Krefting, Jonathan M. Mang, Michael Marschollek, Sebastian Mate, Armin Müller, Fabian Prasser, Julian Sass, Sebastian Semler, Holger Stenzhorn, Sylvia Thun, Sven Zenker, Roland Eils
COVID-19 has challenged the healthcare systems worldwide. To quickly identify successful diagnostic and therapeutic approaches large data sharing approaches are inevitable. Though organizational clinical data are abundant, many of them are available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::910653df95e2e0a8cde1a54a059de463
https://doi.org/10.3233/shti220554
https://doi.org/10.3233/shti220554
Autor:
Christian Quast, Ulrike Wittig, Roland Eils, Uwe Scholz, Sebastian Beier, Gerhard Mayer, Karin Schork, Sven Twardziok, Astrid Junker, Julian Uszkoreit, Alfred Pühler, Jürgen Eils, Daniel Wibberg, Andreas Weidemann, Danuta Schüler, Martin Eisenacher, Janine Felden, Wolfgang Müller, Michael Turewicz, Maja Rey, Hans A. Kestler, Matthias Lange, Frank Oliver Glöckner, Steve Hoffmann, Daniel Arend
Publikováno v:
EPIC3Briefings in Bioinformatics, Oxford University Press (OUP), 22(5), pp. bbab010-, ISSN: 1467-5463
Briefings in Bioinformatics
Briefings in Bioinformatics
This article describes some use case studies and self-assessments of FAIR status of de.NBI services to illustrate the challenges and requirements for the definition of the needs of adhering to the FAIR (findable, accessible, interoperable and reusabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0700d78a69f9a389fcfe28cd8efe15e7
https://doi.org/10.1093/bib/bbab010
https://doi.org/10.1093/bib/bbab010
Autor:
Fabian Pott, Marco Binder, Martin Witzenrath, Christine Goffinet, Sven Laudi, Leif E. Sander, Irina Lehmann, Teresa G Krieger, Saskia Trump, Loreen Thürmann, Johannes Liebig, Sara Hadzibegovic, Robert Lorenz Chua, Uwe G. Liebert, Jan Philipp Albrecht, Lars Kaderali, Sven Twardziok, Christian Conrad, Bianca P Hennig, Bettina Heidecker, Jennifer Loske, Alessia Lena, Markus S. Anker, Naveed Ishaque, Soeren Lukassen, Christian Drosten, Maria Theresa Völker, Christina Klasa, Sarah Dorothea Müller, Marey Messingschlager, Roland Eils, Florian Kurth, Ulf Landmesser, Victor M. Corman, Julia Kazmierski, Jürgen Eils
In COVID-19, hypertension and cardiovascular diseases have emerged as major risk factors for critical disease progression. Concurrently, the impact of the main anti-hypertensive therapies, angiotensin-converting enzyme inhibitors (ACEi) and angiotens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f9c069c41af30f3665a116e93ee3444
https://doi.org/10.1101/2020.09.22.20199471
https://doi.org/10.1101/2020.09.22.20199471
Autor:
Felix Balzer, Bernd Timmermann, Saskia Trump, Naveed Ishaque, Jürgen Eils, Olivia Debnath, Sven Twardziok, Loreen Thürmann, Christian Conrad, Jennifer Loske, Fabian Pott, Uwe G. Liebert, Alexander Krannich, Christof von Kalle, Martin Witzenrath, Sein Schmidt, Robert Lorenz Chua, Florian Kurth, Andreas C. Hocke, Sven Laudi, Christian Drosten, Maria Theresa Völker, Norbert Suttorp, Roland Eils, Stefan Schneider, Irina Lehmann, Melanie Maier, Soeren Lukassen, Daniel Wendisch, Christine Goffinet, Julia Kazmierski, Holger Müller-Redetzky, Leif E. Sander, Felix Machleidt, Bianca P Hennig, Johannes Liebig
Publikováno v:
Nature Biotechnology
To investigate the immune response and mechanisms associated with severe coronavirus disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal and bronchial samples from 19 clinically well-characterized patients with moderate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443e9eaea248f5b90cb8596307d843f7
https://pubmed.ncbi.nlm.nih.gov/32591762
https://pubmed.ncbi.nlm.nih.gov/32591762
Autor:
Loreen Thürmann, Felix Balzer, Jennifer Loske, Bernd Timmermann, Alexander Krannich, Robert Lorenz Chua, Florian Kurth, Christof von Kalle, Sven Laudi, Andreas C. Hocke, Christian Conrad, Johannes Liebig, Martin Witzenrath, Bianca P Hennig, Olivia Debnath, Fabian Pott, Roland Eils, Irina Lehmann, Soeren Lukassen, Naveed Ishaque, Felix Machleidt, Jürgen Eils, Sein Schmidt, Christian Drosten, Julia Kazmierski, Holger Müller-Redetzky, Christine Goffinet, Daniel Wendisch, Stefan Schneider, Sven Twardziok, Saskia Trump, Leif-Erik Sander
The clinical course of COVID-19 is highly variable, however, underlying host factors and determinants of severe disease are still unknown. Based on single-cell transcriptomes of nasopharyngeal and bronchial samples from clinically well-characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354dc25bda203d8d6976f9de93007f43
https://doi.org/10.1101/2020.04.29.20084327
https://doi.org/10.1101/2020.04.29.20084327
Autor:
Nicolas Rodriguez, Sarala M. Wimalaratne, Camille Laibe, Rahuman S Malik-Sheriff, Roland Eils, Robert Hälke, Martin Graesslin, Tung V N Nguyen, Maciej J. Swat, Vijayalakshmi Chelliah, Jochen Schramm, Henning Hermjakob, Nicolas Le Novère, Varun B. Kothamachu, Raza Ali, Jürgen Eils, Mihai Glont
Publikováno v:
Nucleic Acids Research
BioModels serves as a central repository of mathematical models representing biological processes. It offers a platform to make mathematical models easily shareable across the systems modelling community, thereby supporting model reuse. To facilitate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c50fd0bcb6d26f8649114e7f78e1a14
https://doi.org/10.1093/nar/gkx1023
https://doi.org/10.1093/nar/gkx1023