Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jürg Graf"'
Autor:
Wolfgang Jessner, Mario Strazzabosco, Jürg Graf, Carlo Spirli, Ákos Zsembery, Gerlinde Sitter
Publikováno v:
Hepatology. 35:95-104
In view of the occurrence of hepatobiliary disorders in cystic fibrosis (CF) this study addresses the role of the cystic fibrosis transmembrane conductance regulator (CFTR) and of Ca(2+)-activated Cl(-) channels in promoting HCO3- secretion in bile d
Autor:
Rainer ENGLISCH, Reingard WURZINGER, Clemens FÜRNSINN, Barbara SCHNEIDER, Herwig FRISCH, Werner WALDHÄUSL, Jürg GRAF, Michael RODEN
Publikováno v:
Biochemical Journal. 351:39-45
Effects of insulin-like growth factor I (IGF-I) and insulin on glucose and potassium fluxes were examined by measuring transhepatic glucose and potassium balance in isolated perfused rat livers. At 1nM, both IGF-I and insulin decreased basal gluco
Autor:
Kurt Preininger, Harald Stingl, Clemens Fürnsinn, Rainer Englisch, Michael Roden, Werner Waldhäusl, Jürg Graf
Publikováno v:
British Journal of Pharmacology. 126:372-378
The thiazolidinedione compound, troglitazone, enhances insulin action and reduces plasma glucose concentrations when administered chronically to type 2 diabetic patients. To analyse to what extent thiazolidinediones interfere with liver function, we
Autor:
Adrian M. Senderowicz, Jürg Graf, Therese Thalhammer, Bettina Zembsch, Edward A. Sausville, Walter Jäger, Ernst Pittenauer, Peter Wolschann, Hans H. Sedlacek
Publikováno v:
Life Sciences. 62:1861-1873
Flavopiridol (FLAP) is a promising novel chemotherapeutic agent currently undergoing clinical phase I trials. To examine hepatic metabolism and biliary disposition of FLAP we applied the isolated perfused rat liver system. Besides FLAP two metabolite
Autor:
A. Leitner, Reinhold Hirschwehr, Jürg Graf, Otto Scheiner, C. Ebner, B Wüthrich, Erika Jensen-Jarolim, D. Kraft
Publikováno v:
Clinical & Experimental Allergy. 27:1299-1306
Background Symptoms elicited by IgE-mediated food allergy range from mild local to severe systemic reactions. Allergens in spices are particularly dangerous due to their hidden presence in many dishes. Objectives and Methods According to clinical obs
Autor:
D. Niyitegeka, N. Kemka, Serge Hubert Zébazé Togouet, Jürg Graf, Regula Meierhofer, Joseph Gangoue Pieboji
Publikováno v:
Journal of water and health. 8(4)
In developing countries, the burden of diarrhoea is still enormous. One way to reduce transmission of pathogens is by water quality interventions. Solar water disinfection (SODIS) is a low-cost and simple method to improve drinking water quality on h
Publikováno v:
International journal of environmental health research. 18(5)
In this research project, we studied factors that presumably affect the incidence of diarrhoea among young children in urban slums in developing countries: consumption of safe drinks, hygiene behaviour, cleanliness of household surroundings and the q
Autor:
Jürgen Messner, Jürg Graf
Publikováno v:
Wiener medizinische Wochenschrift (1946). 158(19-20)
Recent studies indicate that intracellular insulin signalling involves the formation of reactive oxygen species (ROS) by NADPH oxidases (NOX). ROS inhibit intracellular protein tyrosin phosphatases whereby phosphoprotein signalling is enhanced and pr
Publikováno v:
Wiener medizinische Wochenschrift (1946). 158(19-20)
In the context of the osmotic model of bile formation, we used isolated rat hepatocyte couplets and performed volume measurements by video image analysis to analyze the transport of water between the bile canalicular lumen, liver cells and the surrou
Publikováno v:
Anesthesia and analgesia. 102(2)
Amide local anesthetics mainly undergo hepatic metabolism. Specific applications, such as catheter application for long-term pain therapy, may result in large plasma concentrations. As it is unknown whether local anesthetics influence liver function,