Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Július Benický"'
Autor:
Pritha Mukherjee, Xin Zhou, Susana Galli, Bruce Davidson, Lihua Zhang, Jaeil Ahn, Reem Aljuhani, Julius Benicky, Laurie Ailles, Vitor H. Pomin, Mark Olsen, Radoslav Goldman
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4998 (2024)
Aspartate β-hydroxylase (ASPH) is a protein associated with malignancy in a wide range of tumors. We hypothesize that inhibition of ASPH activity could have anti-tumor properties in patients with head and neck cancer. In this study, we screened tumo
Externí odkaz:
https://doaj.org/article/6d1b9848fe6f4ab58bf0b8b5a3da28ea
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Targeted quantification of glycoproteins has not reached its full potential because of limitations of the existing analytical workflows. In this study, we introduce a targeted microflow LC–MS/MS-PRM method for the quantification of multipl
Externí odkaz:
https://doaj.org/article/e2d85c0463ff47968a6611225e5d0c47
Publikováno v:
Molecules, Vol 27, Iss 7, p 2213 (2022)
Development of high throughput robust methods is a prerequisite for a successful clinical use of LC-MS/MS assays. In earlier studies, we reported that nLC-MS/MS measurement of the O-glycoforms of HPX is an indicator of liver fibrosis. In this study,
Externí odkaz:
https://doaj.org/article/1de20b012f924741807fda46064dbfc1
Publikováno v:
Cellular Physiology and Biochemistry. 16:59-68
Background: The objective was to compare signal transduction pathways exploited by glucose and cell swelling in stimulating insulin secretion. Methods: Isolated rat (Wistar) pancreatic islets were stimulated in vitro by 20 mmol/l glucose or 30% hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cab5083c7d6f282a7ad2ad278e37c25f
https://doi.org/10.1159/000087732
https://doi.org/10.1159/000087732
Autor:
Monte A. Greer, Miroslava Najvirtová, Lahim Baqi, Susan E. Greer, Vladimír Štrbák, Július Benický
Publikováno v:
Cellular Physiology and Biochemistry. 13:113-122
Cell swelling causes an immediate secretory response in various cell types. Induced secretion possesses some unique features suggesting the involvement of a specific signal transduction pathway. The effect of 10-20 microM GdCl3, 100 microM HgCl2, 1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6ec06193fb1dfe2cc5b7227beef5bd
https://doi.org/10.1159/000070255
https://doi.org/10.1159/000070255
Publikováno v:
Life Sciences. 66:629-639
Summary Ethanol exerts profound effects on the endocrine and exocrine pancreas. Some effects of chronic alcohol consumption on insulin secretion in response to glucose load are similar to those of TRH gene disruption. TRH is present in insulin-produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0eff7733a0756d7e87be1623729c77
https://doi.org/10.1016/s0024-3205(99)00635-9
https://doi.org/10.1016/s0024-3205(99)00635-9
Publikováno v:
Life Sciences. 60:865-872
Cell swelling induced by hypotonic medium or small isotonic permeant molecules results in an immediate secretory response in various types of cells. We have expanded exploration of this phenomenon by examining the effect of either isotonic ethanol or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121ded0a733fd2f767a60632d07534dd
https://doi.org/10.1016/s0024-3205(97)00015-5
https://doi.org/10.1016/s0024-3205(97)00015-5
Publikováno v:
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 16(1-3)
The objective was to compare signal transduction pathways exploited by glucose and cell swelling in stimulating insulin secretion.Isolated rat (Wistar) pancreatic islets were stimulated in vitro by 20 mmol/l glucose or 30% hypotonic medium (202 mOsm/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d980f08aec8bd422269f5b53baae5b0
https://pubmed.ncbi.nlm.nih.gov/16121034
https://pubmed.ncbi.nlm.nih.gov/16121034
Publikováno v:
Endocrine. 9(2)
Because chronic ethanol ingestion may perturb thyroid function, we evaluated the effect of 4-wk of oral 10% ethanol ingestion on the hypothalamic-pituitary-thyroid (HPT) axis and septal thyrotropin-releasing hormone (TRH) in 200-g male Wistar rats. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498cd16111a5167cd6cc09628cceaffd
https://pubmed.ncbi.nlm.nih.gov/9867256
https://pubmed.ncbi.nlm.nih.gov/9867256
Publikováno v:
Neurophysiology. 32:188-188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e06d50140b5f47f5e324377bc3a14b9
https://doi.org/10.1007/bf02506564
https://doi.org/10.1007/bf02506564