Pancreas- and Pylorus-Preserving Duodenectomy for Advanced Familial Duodenal Polyposis

Autor: Júlio S. Leite, José Guilherme Tralhão, António Manso, Miguel Fernandes, Inês Cunha, Pedro Amaro

Publikováno v: GE: Portuguese Journal of Gastroenterology, Pp 1-7 (2019)

Most patients with familial adenomatous polyposis (FAP) will develop duodenal polyps and 5% progress to cancer. Those with Spigelman stage IV have a 36% risk of cancer at 10 years. Endoscopic surveillance is necessary with local ablation for early di

Externí odkaz: https://doaj.org/article/2794c5dffbc7474794e7886faed5683a

Nutrição entérica pré-operatória e resultados pós-operatórios em adultos com doença de Crohn: revisão sistemática

Autor: Anabela Rocha, Júlio S. Leite, Paula Lago, Fernando Castro-Poças, Inês Bessa, Marisa D. Santos

Publikováno v: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
GE: Portuguese Journal of Gastroenterology, Pp 1-12 (2018)
GE-Portuguese Journal of Gastroenterology v.26 n.3 2019
GE-Portuguese Journal of Gastroenterology, Volume: 26, Issue: 3, Pages: 184-195, Published: JUN 2019

Background and aim: Enteral nutrition (EN) is applicable to adult Crohn's disease (CD) in treating malnutrition and in inducing remission - here as a less effective alternative than corticosteroids. The purpose of this review is to determine whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709a046708dd4f3d51618986764d9d8d
https://hdl.handle.net/10400.16/2388

Is prophylactic colectomy indicated in patients with MYH-associated polyposis?

Autor: Fernando Regateiro, J. M. Romãozinho, G. Boavida, F. Castro‐Sousa, Pedro Amaro, Glória Isidro, O. Albuquerque, Júlio S. Leite, M. Martins

Publikováno v: Colorectal Disease. 7:327-331

Objectives The MYH gene has recently been associated with multiple colorectal tumours. It participates in the DNA base-excision-repair, avoiding mutations in other genes, namely the APC and Ki-ras. Recently, biallelic MYH mutations have been describe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6b4b527d77631c71ec474d5fdfda2d
https://doi.org/10.1111/j.1463-1318.2005.00811.x

Usefulness of Perfusion CT to Assess Response to Neoadjuvant Combined Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer

Autor: M. Antónia Portilha, Margarida Borrego, Luís Curvo-Semedo, Filipe Caseiro-Alves, Júlio S. Leite, Catarina Ruivo

RATIONALE AND OBJECTIVES: To prospectively evaluate perfusion computed tomography (CT) for assessment of changes in tumor vascularity after chemoradiation therapy (CRT) in locally advanced rectal cancer and to analyze the correlation between baseline

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2081954f2354f374a6a692fa33fcba2
https://hdl.handle.net/10400.4/1204

Four novel MSH2 / MLH1 gene mutations in portuguese HNPCC families

Autor: Isabel Veiga, Fernando Regateiro, S. Almeida, J. Soares, Manuela Baptista, Paulo Matos, Sérgio Castedo, S. Bizarro, Júlio S. Leite, Brendan Marshall, Glória Isidro, M.G. Boavida

Publikováno v: Scopus-Elsevier

Hereditary non-polyposis colorectal cancer (HNPCC) is considered to be determined bygermline mutations in the mismatch repair (MMR) genes, especially MSH2 and MLH1.While screening for mutations in these two genes in HNPCC portuguese families, 3previo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f90e0bdd999df15281eb5dc8192d5e
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033631004&partnerID=MN8TOARS