Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Júlio César Nepomuceno"'
Autor:
Jeyson Césary Lopes, Nayane Moreira Machado, Rosiane Soares Saturnino, Júlio César Nepomuceno
Publikováno v:
Genetics and Molecular Biology, Vol 38, Iss 1, Pp 101-106 (2015)
Pantoprazole® is one of the leading proton pump inhibitors (PPIs) used in the treatment of a variety of diseases related to the upper gastrointestinal tract. However, studies have shown an increased risk of developing gastric cancer, intestinal meta
Externí odkaz:
https://doaj.org/article/eea5a8fc1d07424db1945014089b043e
Autor:
Lysa Nepomuceno Luiz, José Paulo Gagliardi Leite, Jonny Yokosawa, Bruno M Carneiro, Edson Pereira Filho, Thelma Fátima de Mattos Oliveira, Guilherme Ramos Oliveira e Freitas, Lourenço Faria Costa, Nayhanne Tizzo de Paula, Hélio Lopes da Silveira, Júlio César Nepomuceno, Divina Aparecida Oliveira Queiróz
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 105, Iss 5, Pp 712-716 (2010)
Human adenoviruses (HAdV) are a major cause of acute respiratory diseases (ARD), gastroenteritis, conjunctivitis and urinary infections. Between November 2000-April 2007, a total of 468 nasopharyngeal aspirate samples were collected from children wit
Externí odkaz:
https://doaj.org/article/39a54aa44d4d4bb1ad862ba531208de4
Publikováno v:
Genetics and Molecular Biology, Vol 33, Iss 3, Pp 558-563 (2010)
This study investigated the genotoxicity of Lapachol (LAP) evaluated by wing spot test of Drosophila melanogaster in the descendants from standard (ST) and high bioactivation (HB) crosses. This assay detects the loss of heterozygosity of marker genes
Externí odkaz:
https://doaj.org/article/97a6da54bd4a4f1c8724846bdc1d04d8
Autor:
Júlio César Nepomuceno
Publikováno v:
Bioscience Journal, Vol 21, Iss 1 (2006)
Externí odkaz:
https://doaj.org/article/660a643963e44c8487a0a9aac53034c7
Autor:
Victor Constante Oliveira, Mário Antônio Spanó, Alexandre Azenha Alves de Rezende, Sarah Alves Rodrigues Constante, Júlio César Nepomuceno, Priscila Capelari Orsolin
Publikováno v:
Food and Chemical Toxicology. 106:283-291
Metformin (MET) is an anti-diabetic drug used to prevent hepatic glucose release and increase tissue insulin sensitivity. Diabetic cancer patients are on additional therapy with anticancer drugs. Doxorubicin (DXR) is a cancer chemotherapeutic agent t
Publikováno v:
Food and Chemical Toxicology. 90:10-17
Simvastatin is an antilipemic drug that promotes inhibition of HMG-CoA reductase. Simvastatin can also inhibit the formation of other products, such as isoprenoids, conferring additional benefits to this drug, which include antiproliferative, anti-in
Autor:
Paula Marynella Alves Pereira Lima, Mariana Alves Pereira Zóia, Luiz Ricardo Goulart, Yara Cristina de Paiva Maia, Priscila Capelari Orsolin, Deisi L Braga, Júlio César Nepomuceno, Thaise Gonçalves Araújo, Lara Vecchi, Cristina Ribas Fürstenau, Sara Teixeira Soares Mota
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 7
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1879 (2018)
Volume 19
Issue 7
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1879 (2018)
Breast Cancer (BC) encompasses numerous entities with different biological and behavioral characteristics, favored by tumor molecular complexity. Azadirachta indica (neem) presents phenolic compounds, indicating its potential as an antineoplastic com
Autor:
Luísa Mariana Melo Guimarães, Jeyson Césary Lopes, Júlio César Nepomuceno, Robson José de Oliveira Júnior, Sandra Morelli
Publikováno v:
Journal of Pharmacy and Pharmacology. 6
In the search for new anti-tumor agents, exploiting features such as the flexibility of coordination modes of metals have become an alternative strategy for synthesizing pharmaceuticals. It has been shown that the CuDP (copper(II), doxycycline, and 1
Autor:
Priscila Capelari Orsoli, Thaise Gonçalves Araújo, Júlio César Nepomuceno, Paula Marynella Alves Pereira Lima, Douglas Brandão Cardoso
Publikováno v:
Journal of Pharmacy and Pharmacology. 6
Diet represents an important risk factor for tumor development and numerous food dyes have been tested for their carcinogenic potential. Caramel IV colorant and its byproduct, the 4-methylimidazole (4-MI), are part of the composition of cola soft dri
Autor:
Robson José de Oliveira-Júnior, Nayane Moreira Machado, Victor Constante Oliveira, Priscila Capelari Orsolin, R.G. Silva-Oliveira, Sarah Alves Rodrigues Constante, Lorena Polloni, Júlio César Nepomuceno
Publikováno v:
Drug and chemical toxicology. 41(3)
The present study assessed the protective effect of aspirin against carcinogenicity induced by mitomycin C (MMC) by the test for detection of warts/epithelial tumor clones in Drosophila melanogaster. Larvae were treated with different concentrations