Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Júlia Visy"'
Autor:
Katalin Monostory, Anita Rácz, Pál Szabó, István Vincze, Krisztina Németh, Júlia Visy, György G. Ferenczy, Éva Szökő, György T. Balogh, Tamás Tábi, György M. Keserű, Peter Kovacs, Janez Ilaš, Bence Szilágyi
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:1579-1587
d-Amino acid oxidase (DAAO) is a potential target in the treatment of schizophrenia as its inhibition increases brain d-serine level and thus contributes to NMDA receptor activation. Inhibitors of DAAO were sought testing [6+5] type heterocycles and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbaa8df005baa5c10f706a2643bb1b2e
https://doi.org/10.1016/j.bmc.2018.02.004
https://doi.org/10.1016/j.bmc.2018.02.004
Autor:
Júlia Visy, András Kotschy, Balázs Bálint, Ferenc Zsila, Ilona Fitos, Celesztina Domonkos, Rudolf Kassai
Publikováno v:
RSC Advances. 5:53809-53818
A series of new derivatives of the natural β-carboline alkaloid harmine, introducing hydrophobic substituents into positions 7 and 9 were synthesized as potential anticancer agents. Their binding affinities for human serum albumin (HSA) and α1-acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2072256ff5566474d9c6829b90bb15e
https://doi.org/10.1039/c5ra06426k
https://doi.org/10.1039/c5ra06426k
Autor:
Virág Sarnyai, Celesztina Domonkos, Krisztina Németh, Júlia Visy, Lajos Szente, Julianna Szemán, Laszlo Jicsinszky
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 99:16-21
The resolution power of permethylated 6-monoamino-6-monodeoxy-βCD (PMMABCD) – a single isomer, cationic CD derivative – developed previously for chiral analyses in capillary electrophoresis was further studied here. Dansylated amino acids (Dns-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc40112c01df2baf21f5e6abc5f18f6
https://doi.org/10.1016/j.jpba.2014.06.028
https://doi.org/10.1016/j.jpba.2014.06.028
Fatty Acid Modulated Human Serum Albumin Binding of the β-Carboline Alkaloids Norharmane and Harmane
Publikováno v:
Molecular Pharmaceutics. 10:4706-4716
Harmane and norharmane are representative members of the large group of natural β-carboline alkaloids featured with diverse pharmacological activities. In blood, these agents are transported by human serum albumin (HSA) which has a profound impact o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06736cb04c203e1786246b06822843d5
https://doi.org/10.1021/mp400531n
https://doi.org/10.1021/mp400531n
Autor:
Krisztina Németh, Réka Mizsei, Laszlo Jicsinszky, Júlia Visy, Miklós Simonyi, Gábor Tárkányi, Julianna Szemán, Lajos Szente, Orsolya Tőke
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 72:292-298
Inclusion complexes of warfarin enantiomers with permethylated monoamino-β-cyclodextrin (PMMABCD) were characterized using CE and (1)H NMR spectroscopy in aqueous solution. These techniques gave complementary information on the stability and the str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a55b5ff04ddcdae2df2b1f4be858bf9
https://doi.org/10.1016/j.jpba.2012.09.003
https://doi.org/10.1016/j.jpba.2012.09.003
Autor:
Julianna Szemán, Lajos Szente, Gábor Varga, Antal Péter, István Ilisz, Júlia Visy, Gábor Fodor
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 70:71-76
Three β-cyclodextrin-based chiral stationary phases were developed applying novel bonding chemistry. The separation performances of β-cyclodextrin, (R,S)-2-hydroxypropyl-β-cyclodextrin, and permethyl-β-cyclodextrin-based CSPs were compared in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f033d4140065dfbeb0da3289eedf356
https://doi.org/10.1016/j.jpba.2012.05.023
https://doi.org/10.1016/j.jpba.2012.05.023
Autor:
Júlia Visy, Orsolya Kékesi, Péter Fügedi, Gábor Tárkányi, Ilona Fitos, Gabriella Nyitrai, Zsuzsánna Csíki, Krisztina Németh, Julianna Kardos, Péter Keglevich, Ágnes Simon, Ildikó Pál
Publikováno v:
Nanotoxicology. 6:576-586
We report for the first time on neuronal signaling for the evaluation of interactions between native plasmamembrane and polyamidoamine (PAMAM) dendrimers. Generation 5 polycationic (G5-NH(2)), novel β-D-glucopyranose-conjugated G5-NH(2) and generati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0d211f5e9e8c0d9302cd270b649dfb
https://doi.org/10.3109/17435390.2011.591511
https://doi.org/10.3109/17435390.2011.591511
Autor:
Miklós Simonyi, Róbert Iványi, Laszlo Jicsinszky, Júlia Visy, Krisztina Németh, Antal Péter, Enikő Forró, Lajos Szente, Erzsébet Varga, Ferenc Fülöp, Julianna Szemán
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 53:382-388
Chiral separation of 19 pairs of cis-beta-lactam (BL) stereoisomers of pharmacological importance was examined by capillary electrophoresis using cyclodextrin (CD) derivatives. In order to select the most effective conditions separating the highest n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a196cad436a2dd140eed1ec3ccb3d8d8
https://doi.org/10.1016/j.jpba.2010.04.026
https://doi.org/10.1016/j.jpba.2010.04.026
Selective binding interactions of deramciclane to the genetic variants of human α1-acid glycoprotein
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1800:367-372
Background α1-Acid glycoprotein (AGP) plays a decisive role in the serum protein binding of several drugs.Genetic variants of AGP have different ligand binding properties. The binding of deramciclane (DER), a chiral anxiolytic agent, has been studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6334576064dc620e6ebb550d76e77dab
https://doi.org/10.1016/j.bbagen.2009.08.006
https://doi.org/10.1016/j.bbagen.2009.08.006
Autor:
Júlia Visy, Krisztina Németh, Gábor Tárkányi, Miklós Simonyi, Laszlo Jicsinszky, Orsolya Toke, Róbert Iványi, Julianna Szemán, Gábor Varga, Lajos Szente
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 51:84-89
Preparation of (6-monoureido-6-monodeoxy) permethylated beta-cyclodextrin bonded chiral stationary phase from permethylated 6-monoamino-6-monodeoxy-beta-cyclodextrin is described. The optimized chiral stationary phase was evaluated by using HPLC sepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f5d3028ef1cebd93021edcd7395198
https://doi.org/10.1016/j.jpba.2009.08.009
https://doi.org/10.1016/j.jpba.2009.08.009