Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Jørn Eivind Tungen"'
Autor:
Jannicke Irina Nesman, Karoline Gangestad Primdahl, Jørn Eivind Tungen, Fransesco Palmas, Jesmond Dalli, Trond Vidar Hansen
Publikováno v:
Molecules, Vol 24, Iss 18, p 3228 (2019)
PD1n-3 DPA belongs to the protectin family of specialized pro-resolving lipid mediators. The protectins are endogenously formed mediators that display potent anti-inflammatory properties and pro-resolving bioactivities and have attracted interest in
Externí odkaz:
https://doaj.org/article/5b48990239764776bba14109fd05eb98
Publikováno v:
Journal of Natural Products
The resolution of inflammation is governed by the active biosynthesis of specialized pro-resolving mediators using ω-6 and ω-3 polyunsaturated fatty acids as substrates. These mediators act as resolution agonists and display several interesting bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aac015e087eea9adc18cae7811dc0c7
http://europepmc.org/articles/PMC7467816
http://europepmc.org/articles/PMC7467816
Publikováno v:
The Journal of Organic Chemistry. 84:11373-11381
A highly efficient and regioselective bromolactonization protocol is reported. The quantitative formation of synthetically versatile bromolactones occurs in the presence of only 0.1 mol % of an organoselenium compound, coined DECAD herein, within 90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357e1a3ae102afaa57b175637e0901ed
https://doi.org/10.1021/acs.joc.9b01294
https://doi.org/10.1021/acs.joc.9b01294
Autor:
Jesmond Dalli, Romain A. Colas, Nan Chiang, Roberta De Matteis, Markus Kalesse, Lisa Gerstmann, Charles N. Serhan, Anders Vik, Jørn Eivind Tungen, Trond Vidar Hansen
Publikováno v:
Chemistry - A European Journal. 25:1476-1480
New drugs that can resolve inflammation without immunosuppressive effects are at the medicinal chemistry frontier. Pro-resolving endogenously formed small molecules, that is, the resolvins, are excellent candidates displaying such bioactions. The fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd3f1977f2fd8cd5f86325e459f5fc2
https://doi.org/10.1002/chem.201806029
https://doi.org/10.1002/chem.201806029
Autor:
Francesco Palmas, Yngve Stenstrøm, Trond Vidar Hansen, Jeanne Sønderskov, Jørn Eivind Tungen, Charles N. Serhan, Jesmond Dalli
Publikováno v:
Tetrahedron letters
The first total synthesis of the n-3 docosapentaenoic derived oxygenated product MaR2n-3 DPA has been achieved. The 13R and 14S stereogenic centers were introduced using 2-deoxy-d-ribose in a chiral pool strategy. The geometry of the Z,E,E-triene moi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22572b66ecd6d791ac722d779d90f8da
http://europepmc.org/articles/PMC7709930
http://europepmc.org/articles/PMC7709930
Autor:
Jesmond Dalli, Patricia R. Souza, Anders Vik, Trond Vidar Hansen, Jørn Eivind Tungen, Karoline Gangestad Primdahl, Romain A. Colas
Publikováno v:
Org. Biomol. Chem.. 15:8606-8613
PD1n-3 DPA is a specialized pro-resolving lipid mediator that displays potent anti-inflammatory properties and pro-resolving bioactivities. Such naturally occurring compounds are of current interest in biomolecular chemistry and drug discovery. To in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25e629116f0712938a5e20a321c6b3d
https://doi.org/10.1039/c7ob02113e
https://doi.org/10.1039/c7ob02113e
Autor:
Jørn Eivind, Tungen, Lisa, Gerstmann, Anders, Vik, Roberta, De Matteis, Romain Alexandre, Colas, Jesmond, Dalli, Nan, Chiang, Charles Nicholas, Serhan, Markus, Kalesse, Trond Vidar, Hansen
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 25(66)
New drugs that can resolve inflammation without immunosuppressive effects are at the medicinal chemistry frontier. Pro-resolving endogenously formed small molecules, i.e. the resolvins, are excellent candidates displaying such bioactions. The first t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ddebc1d60e9f861a1f3fd38624ea4560
https://pubmed.ncbi.nlm.nih.gov/30511787
https://pubmed.ncbi.nlm.nih.gov/30511787
Publikováno v:
Organicbiomolecular chemistry. 17(12)
The halolactonization reaction is a useful chemical transformation for the construction of lactones from γ- or δ-substituted alkenoic carboxylic acids or carboxylic esters. Traditionally, the stereoselectivity of these reactions has been controlled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdaf182384e2794049ff33cf9cdf1038
https://pubmed.ncbi.nlm.nih.gov/30806424
https://pubmed.ncbi.nlm.nih.gov/30806424
Autor:
Henriette Arnesen, Helen Soedling, Jason Matthews, Thomas Sæther, Hilde I. Nebb, Ingebrigt Sylte, Nadia Nabil Haj-Yasein, Steinar M. Paulsen, Jørn Eivind Tungen, Trond Vidar Hansen
Publikováno v:
Bioorganic & Medicinal Chemistry
Source at https://doi.org/10.1016/j.bmc.2019.07.032. The peroxisome proliferator activated receptors (PPARs) are important drug targets in treatment of metabolic and inflammatory disorders. Fibrates, acting as PPARα agonists, have been widely used l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929e47c2a2ead9d70047410b50f6c37b
http://hdl.handle.net/11250/2618773
http://hdl.handle.net/11250/2618773
Autor:
Jørn Eivind, Tungen, Lisa, Gerstmann, Anders, Vik, Roberta, De Matteis, Romain Alexandre, Colas, Jesmond, Dalli, Nan, Chiang, Charles Nicholas, Serhan, Markus, Kalesse, Trond Vidar, Hansen
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 25(6)
New drugs that can resolve inflammation without immunosuppressive effects are at the medicinal chemistry frontier. Pro-resolving endogenously formed small molecules, that is, the resolvins, are excellent candidates displaying such bioactions. The fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b35dd8af3cc9db131ef9f467890df164
https://pubmed.ncbi.nlm.nih.gov/31774939
https://pubmed.ncbi.nlm.nih.gov/31774939