Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Jørn B, Christensen"'
Autor:
Matteo Tollemeto, Isidro Badillo‐Ramírez, Lasse Højlund Eklund Thamdrup, Yudong Li, Mahdi Ghavami, Tania Patiño Padial, Jørn B. Christensen, Jan vanHest, Anja Boisen
Publikováno v:
Advanced Materials Interfaces, Vol 11, Iss 19, Pp n/a-n/a (2024)
Abstract The optimal performance of drug delivery formulations, including polymeric nanoparticles, relies on particle distribution throughout the body and the interactions with biological barriers, particularly mucosal layers, which often limit their
Externí odkaz:
https://doaj.org/article/36926b89a84b4d319e78485bad13f406
Autor:
Nasir Rasool, Zainib Razzaq, Samreen Gul Khan, Sana Javaid, Naheed Akhtar, Sadaf Mahmood, Jørn B. Christensen, Ataf Ali Altaf, Syed Muhammad Muneeb Anjum, Faleh Alqahtani, Abdullah F. AlAsmari, Imran Imran
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 4, Pp 104610- (2023)
In present work, a series of novel structural hybrids of 1,3,4-oxadiazole and carbamothioate was designed by chemical modification of 2-(4-isobutylphenyl)propanoic acid. Target compounds (7a-f) were synthesized in significant yields (84–88 %) by co
Externí odkaz:
https://doaj.org/article/4fff2ca5debe43c7a7d7ec57b9a22924
Autor:
Lin-Ping Wu, Mario Ficker, Jørn B. Christensen, Dmitri Simberg, Panagiotis N. Trohopoulos, Seyed M. Moghimi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Understanding nanomaterials interactions with complement is important for a number of applications. Here, the authors study the interaction of sub 6 nm dendrimers with complement and show the small dendrimers escape complement activation but do inter
Externí odkaz:
https://doaj.org/article/4434bb5d9dfb49f59c75cce00c6a6d84
Autor:
Ronan Gleeson, Cecilie L. Andersen, Peter Rapta, Peter Machata, Jørn B. Christensen, Ole Hammerich, Stephan P. A. Sauer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3447 (2023)
A test set of N,N,N’,N’-tetrasubstituted p-phenylenediamines are experimentally explored using ESR (electron spin resonance) spectroscopy and analysed from a computational standpoint thereafter. This computational study aims to further aid struct
Externí odkaz:
https://doaj.org/article/daae072c1f0943749ff49efe10495b36
Autor:
Troels Ronco, Line H. Kappel, Maria F. Aragao, Niccolo Biagi, Søren Svenningsen, Jørn B. Christensen, Anders Permin, Lasse Saaby, Kim Holmstrøm, Janne K. Klitgaard, Artur J. Sabat, Viktoria Akkerboom, Monica Monaco, Marco Tinelli, Alexander W. Friedrich, Bimal Jana, Rikke H. Olsen
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Multidrug-resistant pathogens constitute a serious global issue and, therefore, novel antimicrobials with new modes of action are urgently needed. Here, we investigated the effect of a phenothiazine derivative (JBC 1847) with high antimicrobial activ
Externí odkaz:
https://doaj.org/article/a70ca383e2d94fc0aec69fc9b38b1f43
Autor:
Naheed Akhter, Sidra Batool, Samreen Gul Khan, Nasir Rasool, Fozia Anjum, Azhar Rasul, Şevki Adem, Sadaf Mahmood, Aziz ur Rehman, Mehr un Nisa, Zainib Razzaq, Jørn B. Christensen, Mohammed A. S. Abourehab, Syed Adnan Ali Shah, Syahrul Imran
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 211 (2023)
Triazole-based acetamides serve as important scaffolds for various pharmacologically active drugs. In the present work, structural hybrids of 1,2,4-triazole and acetamides were furnished by chemically modifying 2-(4-isobutylphenyl) propanoic acid (1)
Externí odkaz:
https://doaj.org/article/5865bca841d549898243b7223a929eca
Publikováno v:
Tollemeto, M, Huang, Z, Christensen, J B, Mørck Nielsen, H & Harloff-Helleberg, S 2023, ' Mucoadhesive Dendrons Conjugated to Mesoporous Silica Nanoparticles as a Drug Delivery Approach for Orally Administered Biopharmaceuticals ', ACS Applied Materials and Interfaces, vol. 15, no. 7, pp. 8798–8810 . https://doi.org/10.1021/acsami.2c16502
Biological drugs are increasingly important for patients and industry due to their application in the treatment of common and potentially life-threatening diseases such as diabetes, cancer, and obesity. While most marketed biopharmaceuticals today ar
Autor:
Troels Ronco, Francisca Maria Aragao, Lasse Saaby, Jørn B Christensen, Anders Permin, Andrew R Williams, Stig M Thamsborg, Rikke H Olsen
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258207 (2021)
The rapid evolution of antibiotic resistance in Clostridioides difficile and the consequent effects on prevention and treatment of C. difficile infections (CDIs) are matters of concern for public health. Thioridazine, a compound belonging to the phen
Externí odkaz:
https://doaj.org/article/6ea30fd443644510893431c84e425e63
Autor:
Troels Ronco, Nadia S. Jørgensen, Iben Holmer, Sofie Kromann, Ehsan Sheikhsamani, Anders Permin, Søren W. Svenningsen, Jørn B. Christensen, Rikke H. Olsen
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The emergence of multidrug-resistant bacteria constitutes a significant public health issue worldwide. Consequently, there is an urgent clinical need for novel treatment solutions. It has been shown in vitro that phenothiazines can act as adjuvants t
Externí odkaz:
https://doaj.org/article/4d6b0c7061f34535987391644f15425a
Publikováno v:
Advanced Nanoformulations ISBN: 9780323857857
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c98d83675ea61a1d1bb830ff6432373
https://doi.org/10.1016/b978-0-323-85785-7.00008-5
https://doi.org/10.1016/b978-0-323-85785-7.00008-5