Zobrazeno 1 - 10
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pro vyhledávání: '"Jørgen Fogh"'
Autor:
Jorgen Fogh
The study of cultured human tumor cells is a most obvious approach in experimental human cancer research. For many techniques in virology, immunology, biochemistry, and biophysics, for example, large amounts of cells may be required and such quantiti
Autor:
Francis E. Sharkey, Jørgen Fogh
Publikováno v:
Cancer and Metastasis Review. 3:341-360
Transplants of human tumors in nude mice have shown a progressive increase during the past 15 years as an experimental model for cancer research. A variety of factors, including relatively fragile health, have been identified that require appropriate
Publikováno v:
Experimental Biology and Medicine. 162:503-509
SummaryConcordance of polymorphic enzyme phenotypes in various comparisons of human normal and malignant cells in vitro and in vivo establishes isozyme stability after change to the malignant state and after long-term tissue culture. Such enzymes, th
Publikováno v:
Pathobiology. 48:229-239
Subcutaneous inoculation of 87 human tumors into athymic nude mice, including gastrointestinal (non-colon) tumors, germ cell-primitive cell tumors, kidney tumors, lower urinary tract tumors, malignant melanomas and several metastases from unknown pri
Autor:
Kenji Shimizu, Manuel Perucho, Y. Suard, Ed Stavnezer, Mitchell Goldfarb, Jørgen Fogh, Yen Hsing Li, Tohru Kamata, Jim Feramisco, Michael Wigler
Publikováno v:
Scopus-Elsevier
Three distinct transforming genes present in human tumor cell lines are all related to the viral oncogenes of Harvey and Kirsten murine sarcoma viruses, designated v-H-ras and v-K-ras, respectively. The transforming gene of a bladder carcinoma cell l
Publikováno v:
JNCI: Journal of the National Cancer Institute. 66:1003-1012
Forty-six cultured cell lines of diverse human tumor origins, including 25 melanoma cell lines, were HLA allotyped with the use of a modified eosin complement-dependent cytotoxicity test in combination with absorption and two-color fluorescence techn
Publikováno v:
Pathobiology. 53:100-106
Differing conclusions have been reached regarding the phenotypic stability of human tumors transplanted to athymic nude mice. Since previous conflicting studies of tumor histology have been largely subjective, quantitative methodology was applied to
Autor:
Jørgen Fogh, James D. Loveless
Publikováno v:
JNCI: Journal of the National Cancer Institute. 60:887-893
Sixteen established cell lines of simian virus 40 (SV40)-transformed human amnion cells were examined for SV40 production. Many of these lines produced SV40 for extensive periods. Virus production had not ceased for 2 lines after 18 months, for 3 lin
Publikováno v:
JNCI: Journal of the National Cancer Institute. 58:209-214
Numerous cell lines derived from human tumors are not HeLa contaminants. Of 192 lines established in this or other laboratories, 169 lines were found to be G6PD type B. Twenty-three lines were type A as HeLa; three of these were of Negroid origin. Th
Publikováno v:
Cancer Genetics and Cytogenetics. 16:189-197
Chromosome banding analysis was attempted on tumor cells from a total of six rhabdomyosarcomas. Results revealed a variety of chromosome alterations, including frequent structural rearrangement of chromosome #1 and the finding in one patient of multi