Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jörn Sven Kühl"'
Autor:
Isabelle Weinhofer, Paulus Rommer, Andreas Gleiss, Markus Ponleitner, Bettina Zierfuss, Petra Waidhofer-Söllner, Stéphane Fourcade, Katharina Grabmeier-Pfistershammer, Marie-Christine Reinert, Jens Göpfert, Anne Heine, Hemmo A.F. Yska, Carlos Casasnovas, Verónica Cantarín, Caroline G. Bergner, Eric Mallack, Sonja Forss-Petter, Patrick Aubourg, Annette Bley, Marc Engelen, Florian Eichler, Troy C. Lund, Aurora Pujol, Wolfgang Köhler, Jörn-Sven Kühl, Johannes Berger
Publikováno v:
EBioMedicine, Vol 96, Iss , Pp 104781- (2023)
Summary: Background: X-linked adrenoleukodystrophy (X-ALD) is highly variable, ranging from slowly progressive adrenomyeloneuropathy to severe brain demyelination and inflammation (cerebral ALD, CALD) affecting males with childhood peak onset. Risk m
Externí odkaz:
https://doaj.org/article/275297f07de64a75ad4b82604a75b650
Autor:
Isabelle Weinhofer, Agnieszka Buda, Markus Kunze, Zsofia Palfi, Matthäus Traunfellner, Sarah Hesse, Andrea Villoria-Gonzalez, Jörg Hofmann, Simon Hametner, Günther Regelsberger, Ann B. Moser, Florian Eichler, Stephan Kemp, Jan Bauer, Jörn-Sven Kühl, Sonja Forss-Petter, Johannes Berger
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Using Epstein-Barr virus (EBV) infection of human B cells, the importance of peroxisomal very long-chain fatty acid transport involving ABCD1 in viral infection and host defence is elucidated and applicable also to other herpes- and coronaviruses.
Externí odkaz:
https://doaj.org/article/cafeb30b8fac40d4ab823716a9b46cab
Autor:
Caroline G. Bergner, Lisa Schäfer, Vladan Vucinic, Birthe Schetschorke, Julia Lier, Cordula Scherlach, Michael Rullmann, Osama Sabri, Joseph Classen, Uwe Platzbecker, Jörn-Sven Kühl, Henryk Barthel, Wolfgang Köhler, Georg-Nikolaus Franke
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
CSF1 receptor-related leukoencephalopathy is a rare genetic disorder presenting with severe, adult-onset white matter dementia as one of the leading symptoms. Within the central nervous system, the affected CSF1-receptor is expressed exclusively in m
Externí odkaz:
https://doaj.org/article/d1748348c342489cac6dc03a759cd654
Autor:
Bettina Zierfuss, Isabelle Weinhofer, Jörn‐Sven Kühl, Wolfgang Köhler, Annette Bley, Katharina Zauner, Johannes Binder, Ksenija Martinović, Christian Seiser, Christoph Hertzberg, Stephan Kemp, Gerda Egger, Gerda Leitner, Jan Bauer, Christoph Wiesinger, Markus Kunze, Sonja Forss‐Petter, Johannes Berger
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 5, Pp 639-652 (2020)
Abstract Objective To identify a pharmacological compound targeting macrophages, the most affected immune cells in inflammatory X‐linked adrenoleukodystrophy (cerebral X‐ALD) caused by ABCD1 mutations and involved in the success of hematopoietic
Externí odkaz:
https://doaj.org/article/25a19368269e4040bd9f1f687a1e1952
Autor:
Jörn-Sven Kühl, Schepper, Florian, Herrmann, Jessy, Martini, Julia, Santel, Anja, Herzog, Kristina
In this project, we sought to evaluate the psychometric properties of the Fear of Progression Questionnaire for children which aims to assess the level of Fear of Progression in paediatric cancer patients. Children aged 4-18 years suffering from canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d3a6f3c1786882102f487a529c1e601
Autor:
Christine N. Duncan, Jörn-Sven Kühl, Robert Chiesa, Jaap-Jan Boelens, Florian Eichler, Caroline Sevin, Jean-Hugues Dalle, Satiro N. De Oliveira, Hernan M. Amartino, Neena Kapoor, Vinod K. Prasad, Simon Jones, Mattia Algeri, Nancy J. Bunin, Cristina Diaz-de-Heredia, Adrian J. Thrasher, Juliana Folloni Fernandes, Nicholas Smith, Ami J Shah, Franco Locatelli, Marc Engelen, Caroline A. Lindemans, Andrew C. Dietz, Lin Pan, Jakob Sieker, David A. Williams, Paul J. Orchard
Publikováno v:
Transplantation and Cellular Therapy. 28:S2-S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18b46d4287bb7aff695cf8f2232f64b4
https://doi.org/10.1016/s2666-6367(22)00164-6
https://doi.org/10.1016/s2666-6367(22)00164-6
Autor:
Dirk Boehmer, Arend von Stackelberg, Jörn-Sven Kühl, Arne Gruen, Volker Budach, Sebastian Exner, Carmen Stromberger
Publikováno v:
Strahlentherapie Und Onkologie
Background Total body irradiation (TBI) is an established part of conditioning regimens prior to stem cell transplantation in childhood leukemia but is associated with long-term toxicity. We retrospectively analyzed survival, long-term toxicity, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046e751488556a7eb94ea31283f5d5a9
https://doi.org/10.1007/s00066-021-01810-4
https://doi.org/10.1007/s00066-021-01810-4
Autor:
Anna Eichinger, Ulrike Poetschger, Evgenia Glogova, Peter Bader, Oliver Basu, Rita Beier, Birgit Burkhardt, Carl-Friedrich Classen, Alexander Claviez, Selim Corbacioglu, Hedwig E. Deubzer, Johann Greil, Bernd Gruhn, Tayfun Güngör, Kinan Kafa, Jörn-Sven Kühl, Peter Lang, Bjoern Soenke Lange, Roland Meisel, Ingo Müller, Martin G. Sauer, Paul-Gerhardt Schlegel, Ansgar Schulz, Daniel Stachel, Brigitte Strahm, Angela Wawer, Christina Peters, Michael H. Albert
Publikováno v:
Leukemia. 36(11)
Total body irradiation (TBI)-based conditioning is associated with superior leukemia-free survival in children with ALL undergoing HSCT. However, the risk for subsequent malignant neoplasms (SMN) remains a significant concern. We analyzed 705 pediatr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32935b738c9e4082a24eaba4aff880f6
https://pubmed.ncbi.nlm.nih.gov/36097283
https://pubmed.ncbi.nlm.nih.gov/36097283
Autor:
Karoline Ehlert, Johannes H. Schulte, Jörn-Sven Kühl, Sebastian Voigt, Angelika Eggert, Peter Lang
Publikováno v:
Journal of the Pediatric Infectious Diseases Society.
Background Adenovirus (AdV) infections are of particular concern in pediatric hematopoietic stem cell transplantation (HSCT) recipients as therapeutic options are limited. Brincidofovir (BCV) is the lipid-conjugated pro-drug of cidofovir (CDV) with o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdbd0a22923e41244b9a88fa84bd7ac
https://doi.org/10.1093/jpids/piab072
https://doi.org/10.1093/jpids/piab072
Autor:
Wolfgang Brück, Caroline G. Bergner, Martin S. Weber, Nafiye Genc, Franziska van der Meer, Jörn-Sven Kühl, Wolfgang Köhler, Christine Stadelmann, Gisela Stoltenburg-Didinger, Simon Hametner, Jonas Franz, Miso Mitkovski, Jutta Gärtner
Publikováno v:
Glia
Cerebral disease manifestation occurs in about two thirds of males with X-linked adrenoleukodystrophy (CALD) and is fatally progressive if left untreated. Early histopathologic studies categorized CALD as an inflammatory demyelinating disease, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75087f88a3df9e6e8e8970bd5d85a551
https://pubmed.ncbi.nlm.nih.gov/34137074
https://pubmed.ncbi.nlm.nih.gov/34137074