Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jörn Lewin"'
Autor:
Jörn Lewin, Denise Kottwitz, Johanna Aoyama, Theo deVos, Jorge Garces, Oliver Hasinger, Stefanie Kasielke, Florian Knaust, Preeti Rathi, Sebastian Rausch, Gunter Weiss, Alexander Zipprich, Edward Mena, Tse-Ling Fong
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Hepatocellular carcinoma (HCC) is the leading cause of death in patients with cirrhosis, primarily due to failed early detection. HCC screening is recommended among individuals with cirrhosis using biannual abdominal ultrasound, f
Externí odkaz:
https://doaj.org/article/3d6ec220036e47cd95d5ef53bc9a5bcb
Autor:
Christoph Kneip, Bernd Schmidt, Michael Fleischhacker, Anke Seegebarth, Jörn Lewin, Nadja Flemming, Stefanie Seemann, Thomas Schlegel, Christian Witt, Volker Liebenberg, Dimo Dietrich
Publikováno v:
BioTechniques, Vol 47, Iss 3, Pp 737-744 (2009)
DNA methylation is an important epigenetic mechanism involved in fundamental biological processes such as development, imprinting, and carcino-genesis. For these reasons, DNA methylation represents a valuable source for cancer biomarkers. Methods for
Externí odkaz:
https://doaj.org/article/4802c36b2bef417d9a0fd54805aa8b04
Autor:
Rene Cortese, Jörn Lewin, Liselotte Bäckdahl, Manuel Krispin, Reinhold Wasserkort, Florian Eckhardt, Stephan Beck
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26002 (2011)
Cellular differentiation involves widespread epigenetic reprogramming, including modulation of DNA methylation patterns. Using Differential Methylation Hybridization (DMH) in combination with a custom DMH array containing 51,243 features covering mor
Externí odkaz:
https://doaj.org/article/ca5f1967b3e042e6856813298b5b5d96
Autor:
Vardhman K Rakyan, Thomas Hildmann, Karen L Novik, Jörn Lewin, Jörg Tost, Antony V Cox, T Dan Andrews, Kevin L Howe, Thomas Otto, Alexander Olek, Judith Fischer, Ivo G Gut, Kurt Berlin, Stephan Beck
Publikováno v:
PLoS Biology, Vol 2, Iss 12, p e405 (2004)
The Human Epigenome Project aims to identify, catalogue, and interpret genome-wide DNA methylation phenomena. Occurring naturally on cytosine bases at cytosine-guanine dinucleotides, DNA methylation is intimately involved in diverse biological proces
Externí odkaz:
https://doaj.org/article/2cf00ba41d244a9caba9210bb644349d
Autor:
Stefanie Kasielke, Johanna Aoyama, Alexander Zipprich, Florian Knaust, Jörn Lewin, Denise Kottwitz, Theo deVos, Tse-Ling Fong, Edward Mena, Jorge Garces, Oliver Hasinger, Gunter Weiss, Preeti Rathi, Sebastian Rausch
Publikováno v:
BMC Gastroenterology
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-8 (2021)
Background Hepatocellular carcinoma (HCC) is the leading cause of death in patients with cirrhosis, primarily due to failed early detection. HCC screening is recommended among individuals with cirrhosis using biannual abdominal ultrasound, for earlie
Autor:
Wilfred F. J. van IJcken, Joyce B. J. van Meurs, Fan Liu, Dmitry Zubakov, André G. Uitterlinden, Iris Kokmeijer, Manfred Kayser, Cornelia M. van Duijn, Ying Choi, Linda Broer, Albert Hofman, Jörn Lewin
Publikováno v:
Forensic Science International: Genetics, 24, 33-43. Elsevier Ireland Ltd
Establishing the age of unknown persons, or persons with unknown age, can provide important leads in police investigations, disaster victim identification, fraud cases, and in other legal affairs. Previous methods mostly relied on morphological featu
Autor:
Thomas Schlegel, Dimo Dietrich, Jörn Lewin, Anke Seegebarth, Stefanie Seemann, Christian Witt, Michael Fleischhacker, Bernd Schmidt, Nadja Flemming, Volker Liebenberg, Christoph Kneip
Publikováno v:
BioTechniques. 47:737-744
DNA methylation is an important epigenetic mechanism involved in fundamental biological processes such as development, imprinting, and carcino-genesis. For these reasons, DNA methylation represents a valuable source for cancer biomarkers. Methods for
Autor:
Triantafillos Liloglou, Bernd Schmidt, Dimo Dietrich, Sabine Weickmann, Reimo Tetzner, Christian Witt, Volker Liebenberg, Martin Walshaw, Jürgen Distler, Anke Seegebarth, Stefanie Seemann, Olaide Y. Raji, Jörn Lewin, Michael Fleischhacker, Thomas Schlegel, Nadja Flemming, Christoph Kneip, Ulrike Wille, John K. Field
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 600 (2010)
BMC Cancer
BMC Cancer
Background This study aimed to show that SHOX2 DNA methylation is a tumor marker in patients with suspected lung cancer by using bronchial fluid aspirated during bronchoscopy. Such a biomarker would be clinically valuable, especially when, following
Autor:
Anne, Fassbender, Jörn, Lewin, Thomas, König, Tamas, Rujan, Cecile, Pelet, Ralf, Lesche, Jürgen, Distler, Matthias, Schuster
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 576
Recently, the analysis and functional elucidation of CpG island methylation has become a focus area of genomic research. Deviations from the normal parental imprinting pattern have been shown to cause developmental defects associated with serious sym