Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jörn Karhausen"'
Autor:
Janessa Y.J. Tan, Danielle E. Anderson, Abhay P.S. Rathore, Aled O’Neill, Chinmay Kumar Mantri, Wilfried A.A. Saron, Cheryl Q.E. Lee, Chu Wern Cui, Adrian E.Z. Kang, Randy Foo, Shirin Kalimuddin, Jenny G. Low, Lena Ho, Paul Tambyah, Thomas W. Burke, Christopher W. Woods, Kuan Rong Chan, Jörn Karhausen, Ashley L. St. John
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
Lung inflammation is a hallmark of Coronavirus disease 2019 (COVID-19) in patients who are severely ill, and the pathophysiology of disease is thought to be immune mediated. Mast cells (MCs) are polyfunctional immune cells present in the airways, whe
Externí odkaz:
https://doaj.org/article/0ded7096dad04c348c5c375637996e23
Autor:
Maorong Jiang, Ran Li, Jingjun Lyu, Xuan Li, Wei Wang, Zhuoran Wang, Huaxin Sheng, Weiguo Zhang, Jörn Karhausen, Wei Yang
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background Cardiac arrest (CA) is associated with high morbidity and mortality, even after spontaneous circulation is re-established. This dire situation is partly due to post-CA syndrome for which no specific and effective intervention is a
Externí odkaz:
https://doaj.org/article/6b94a45d2a344ca68fd2282e26383ff6
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Conjugation with the small ubiquitin-like modifier (SUMO) constitutes a key post-translational modification regulating the stability, activity, and subcellular localization of its target proteins. However, the vast numbers of identified SUMO substrat
Externí odkaz:
https://doaj.org/article/ea6aa8caa7fa4d4ea1391fbf84ed293c
Autor:
Zhuoran Wang, Wei Wang, Wei Yang, Xuan Li, Weiguo Zhang, Maorong Jiang, Huaxin Sheng, Jingjun Lyu, Ran Li, Jörn Karhausen
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-12 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
BackgroundCardiac arrest (CA) is associated with high morbidity and mortality, even after spontaneous circulation is re-established. This dire situation is partly due to post-CA syndrome for which no specific and effective intervention is available.
Autor:
Yuntian Shen, Wei Wang, Wei Yang, Zhuoran Wang, Qiang Zhao, Jörn Karhausen, Qiang Liu, Maorong Jiang, Weiguo Zhang, Ran Li, Huaxin Sheng, Ulrike Hoffmann, Liping Lu, Jiangbo Wu, Jingjun Lyu, Minghua Zhu
Publikováno v:
J Cereb Blood Flow Metab
In patients who are successfully resuscitated after initial cardiac arrest (CA), mortality and morbidity rates are high, due to ischemia/reperfusion injury to the whole body including the nervous and immune systems. How the interactions between these
Autor:
Jatin Anand, Ehsan Benrashid, Oliver K. Jawitz, Jeffrey G. Gaca, David N. Ranney, G. Chad Hughes, Julie Doberne, Andrew M. Vekstein, Jeffrey E. Keenan, Jörn Karhausen, Jacob N. Schroder, Babtunde A Yerokun, Hanghang Wang
Publikováno v:
Eur J Cardiothorac Surg
OBJECTIVES The impact of hypothermic circulatory arrest (HCA) temperature on postoperative acute kidney injury (AKI) has not been evaluated. This study examined the association between circulatory arrest temperatures and AKI in patients undergoing pr
Autor:
Miklos D. Kertai, Manuel L. Fontes, Mark Stafford-Smith, Srikar Rao, Alan M. Smeltz, Mary Cooter, Jörn Karhausen
Publikováno v:
Journal of Cardiothoracic and Vascular Anesthesia. 32:1214-1224
To explore whether baseline pulse pressure (PP) confers an increased risk for acute kidney injury (AKI) independent of intraoperative hypotension or hypertension in patients who undergo coronary artery bypass grafting (CABG) surgery.Retrospective stu
Autor:
Miklos D. Kertai, Adriana D. Oprea, Mary Cooter, Mihai V. Podgoreanu, Patrick Nailer, Jörn Karhausen, J. Mauricio Del Rio, Manuel L. Fontes, Mark Stafford-Smith, Nicole R. Guinn, Jacob N. Schroder, Cynthia L. Green
Publikováno v:
Canadian Journal of Anesthesia/Journal canadien d'anesthésie. 65:46-59
Preoperative and postoperative anemia have been identified individually as potential risk factors for postoperative complications after coronary artery bypass grafting (CABG) surgery. Their interrelationship with acute kidney injury (AKI) and long-te
Autor:
Robert H. Lee, Joseph P. Mathew, Jörn Karhausen, Hae Woong Choi, Yacine Boulaftali, Krishna Rao Maddipati, Qing Ma, Wolfgang Bergmeier, Soman N. Abraham
Publikováno v:
Science Advances
Activated platelets cause microvascular inflammation via direct activation of perivascular mast cells.
Platelet responses have been associated with end-organ injury and mortality following complex insults such as cardiac surgery, but how platele
Platelet responses have been associated with end-organ injury and mortality following complex insults such as cardiac surgery, but how platele
Autor:
Mihai V. Podgoreanu, Jerrold H. Levy, Jeffrey G. Gaca, Shan Zhou, Jörn Karhausen, Manuel L. Fontes, William D. White, Miklos D. Kertai, Mark Stafford-Smith, Ian J. Welsby, Mary Cooter, Yi-Ju Li, Joseph P. Mathew, Edmund H. Jooste, Solomon Aronson
Publikováno v:
Anesthesiology. 124:339-352
Background Cardiac surgery requiring cardiopulmonary bypass is associated with platelet activation. Because platelets are increasingly recognized as important effectors of ischemia and end-organ inflammatory injury, the authors explored whether posto