Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jörn, Saupe"'
Autor:
Anne Lesage, Christoph Gibson, François Marceau, Horst-Dieter Ambrosi, Jörn Saupe, Werner Katzer, Brigitte Loenders, Xavier Charest-Morin, Jochen Knolle
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
We here report the discovery and early characterization of Compound 3, a representative of a novel class of small molecule bradykinin (BK) B2 receptor antagonists, and its superior profile to the prior art B2 receptor antagonists Compound 1 and Compo
Externí odkaz:
https://doaj.org/article/92e7f5a02ede42aebfed681c18b87a99
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
Externí odkaz:
https://doaj.org/article/ec06792070a34f04867f8c2d6a669668
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
An Ugi multicomponent reaction with chiral cyclic amino acids, benzyl isocyanide and cyclic ketones (or acetone) has been exploited as key step for the generation of peptidomimetics. After a straightforward set of elaborations, the peptidomimetics we
Externí odkaz:
https://doaj.org/article/a7ee0e49accd4b4a9217a59cbf0da7e7
Autor:
Anne, Lesage, François, Marceau, Christoph, Gibson, Brigitte, Loenders, Werner, Katzer, Horst-Dieter, Ambrosi, Jörn, Saupe, Alexander, Faussner, Evangelia, Pardali, Jochen, Knolle
Publikováno v:
International immunopharmacology. 105
PHA-022121 is a novel small molecule bradykinin B
Autor:
Nestor Kamdem, Yvette Roske, Dmytro Kovalskyy, Maxim O. Platonov, Oleksii Balinskyi, Annika Kreuchwig, Jörn Saupe, Liang Fang, Anne Diehl, Peter Schmieder, Gerd Krause, Jörg Rademann, Udo Heinemann, Walter Birchmeier, Hartmut Oschkinat
Publikováno v:
Magnetic resonance, 2(1):355-374
Dishevelled (Dvl) proteins are important regulators of the Wnt signalling pathway, interacting through their PDZ domains with the Wnt receptor Frizzled. Blocking the Dvl PDZ–Frizzled interaction represents a potential approach for cancer treatment,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6e3aced6420c815950ecd12d6a7af1
https://mr.copernicus.org/articles/2/355/2021/
https://mr.copernicus.org/articles/2/355/2021/
Autor:
Nestor Kamdem, Yvette Roske, Dmytro Kovalskyy, Maxim O. Platonov, Oleksii Balinskyi, Annika Kreuchwig, Jörn Saupe, Liang Fang, Anne Diehl, Peter Schmieder, Gerd Krause, Jörg Rademann, Udo Heinemann, Walter Birchmeier, Hartmut Oschkinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fdc86dbc1083396b0b38977e9cc22a0
https://doi.org/10.5194/mr-2021-20-supplement
https://doi.org/10.5194/mr-2021-20-supplement
Autor:
Anne Lesage, François Marceau, Christoph Gibson, Brigitte Loenders, Werner Katzer, Horst-Dieter Ambrosi, Jörn Saupe, Alexander Faussner, Evangelia Pardali, Jochen Knolle
Publikováno v:
International Immunopharmacology. 105:108523
Autor:
Christoph Gibson, Xavier Charest-Morin, Brigitte Loenders, Jörn Saupe, Werner Katzer, Horst-Dieter Ambrosi, Jochen Knolle, Anne Lesage, François Marceau
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology, Vol 11 (2020)
We here report the discovery and early characterization of Compound 3, a representative of a novel class of small molecule bradykinin (BK) B2 receptor antagonists, and its superior profile to the prior art B2 receptor antagonists Compound 1 and Compo
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Macrocycles are a structural class bearing great promise for future challenges in medicinal chemistry. Nevertheless, there are few flexible approaches for the rapid generation of structurally diverse macrocyclic compound collections. Here, an efficie
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 6 (2018)
Frontiers in Chemistry, Vol 6 (2018)
An Ugi multicomponent reaction with chiral cyclic amino acids, benzyl isocyanide and cyclic ketones (or acetone) has been exploited as key step for the generation of peptidomimetics. After a straightforward set of elaborations, the peptidomimetics we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e8b7d7662f8decfbd3b11580d1f39e
http://hdl.handle.net/11567/923058
http://hdl.handle.net/11567/923058