Zobrazeno 1 - 10
of 657
pro vyhledávání: '"Jörg-Dieter Schulzke"'
Autor:
Markus M. Heimesaat, Soraya Mousavi, Fábia Daniela Lobo de Sá, Elisa Peh, Jörg-Dieter Schulzke, Roland Bücker, Sophie Kittler, Stefan Bereswill
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHuman infections with the food-borne enteropathogen Campylobacter jejuni are responsible for increasing incidences of acute campylobacteriosis cases worldwide. Since antibiotic treatment is usually not indicated and the severity of the en
Externí odkaz:
https://doaj.org/article/e8ff160ec5e940a5ad797d8f772da427
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The oleoresin myrrh has been used for centuries as an anti-inflammatory remedy for a variety of diseases and is said to have a protective effect on the intestinal epithelium. An intact epithelial barrier function is the prerequisite for a healthy gut
Externí odkaz:
https://doaj.org/article/c1551ed713084d9eb5896e7ea39a868d
Autor:
Karem Awad, Christian Barmeyer, Christian Bojarski, Oliver Nagel, In-Fah M. Lee, Michal R. Schweiger, Jörg-Dieter Schulzke, Roland Bücker
Publikováno v:
Cells, Vol 12, Iss 24, p 2846 (2023)
Background: In patients with diarrhea-predominant irritable bowel syndrome (IBS-D), the diarrheal mechanisms are largely unknown, and they were examined in this study on colon biopsies. Methods: Electrophysiological measurements were used for monitor
Externí odkaz:
https://doaj.org/article/617ff395507043f5b1568681be88f5b2
Autor:
Martina Schneemann, Lucas Heils, Verena Moos, Franziska Weiß, Susanne M. Krug, January Weiner, Dieter Beule, Ralf Gerhard, Jörg-Dieter Schulzke, Roland Bücker
Publikováno v:
Toxins, Vol 15, Iss 11, p 643 (2023)
Background: Clostridioides difficile toxins TcdA and TcdB are responsible for diarrhea and colitis. Lack of functional studies in organoid models of the gut prompted us to elucidate the toxin’s effects on epithelial barrier function and the molecul
Externí odkaz:
https://doaj.org/article/7f3885d1b10448c8ab6e17773d112dc2
Autor:
Susanne M. Krug, Carolin Grünhagen, Kristina Allers, Christian Bojarski, Joachim Seybold, Thomas Schneider, Jörg-Dieter Schulzke, Hans-Jörg Epple
Publikováno v:
Cells, Vol 12, Iss 14, p 1887 (2023)
Based on indirect evidence, increased mucosal translocation of gut-derived microbial macromolecules has been proposed as an important pathomechanism in HIV infection. Here, we quantified macromolecule translocation across intestinal mucosa from treat
Externí odkaz:
https://doaj.org/article/c5c79210e68047a584b8e58bbdbdbc28
Autor:
Jia-Chen E. Hu, Franziska Weiß, Christian Bojarski, Federica Branchi, Jörg-Dieter Schulzke, Michael Fromm, Susanne M. Krug
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Ulcerative colitis (UC) has a relapsing and remitting pattern, wherein the underlying mechanisms of the relapse might involve an enhanced uptake of luminal antigens which stimulate the immune response. The tricellular tight juncti
Externí odkaz:
https://doaj.org/article/34df0e68687349aea2f0d276e6d12885
Autor:
Sholpan Omarova, Karem Awad, Verena Moos, Christoph Püning, Greta Gölz, Jörg-Dieter Schulzke, Roland Bücker
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 449 (2023)
Background: Campylobacter jejuni (C. jejuni) is one of the most common causes of bacterial gastroenteritis worldwide. One sequela of this infection is the development of post-infectious irritable bowel syndrome (PI-IBS). It has been suggested that a
Externí odkaz:
https://doaj.org/article/ddaf1b3fc17e454ead32bb2de7386bdd
Publikováno v:
Toxins, Vol 15, Iss 1, p 54 (2023)
Background: Clostridioides difficile binary toxin (CDT) defines the hypervirulence of strains in nosocomial antibiotic-induced colitis with the highest mortality. The objective of our study was to investigate the impact of CDT on the intestinal epith
Externí odkaz:
https://doaj.org/article/9eafaf262bde45dd81a66527a814f11b
Autor:
Karem Awad, Christian Barmeyer, Christian Bojarski, Oliver Nagel, In-Fah M. Lee, Michal R. Schweiger, Jörg-Dieter Schulzke, Roland Bücker
Publikováno v:
Cells, Vol 12, Iss 2, p 236 (2023)
Background: The underlying pathophysiology of irritable bowel syndrome (IBS) is still unclear. Our aim was to investigate the pathophysiological mechanisms of diarrhea, constipation, and antigen uptake in mixed-type IBS (IBS-M). Methods: Colonoscopic
Externí odkaz:
https://doaj.org/article/6dc6f099552e46198939f9832ba91002
Autor:
Tatjana Zejc, Jörg Piontek, Jörg-Dieter Schulzke, Michael Fromm, Jürgen Ervens, Rita Rosenthal
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11234 (2022)
A change in claudin expression has been demonstrated in various tumors. The present study specifically compares claudin expression in oral squamous cell carcinoma (OSCC) with healthy oral epithelium from the same individual and analyzes the associati
Externí odkaz:
https://doaj.org/article/108bbfebf9514dd693c527029efac69a