Výsledky vyhledávání - "Jörg Th. Hartmann"

Microsatellite Instability, Mismatch Repair Deficiency, and BRAF Mutation in Treatment-Resistant Germ Cell Tumors

Autor: Ewout W. Steyerberg, Ad J. M. Gillis, Karin Oechsle, Ruud J H L M van Gurp, Carsten Bokemeyer, Leendert H. J. Looijenga, J. Wolter Oosterhuis, Frank Mayer, Friedemann Honecker, Jörg Th. Hartmann, Winand N.M. Dinjens, Hans Stoop, Hendrik Wermann

Publikováno v: Journal of Clinical Oncology. 27:2129-2136

Purpose Mismatch repair (MMR) deficiency and microsatellite instability (MSI) are associated with cisplatin resistance in human germ cell tumors (GCTs). BRAF mutation (V600E) is found in MSI colorectal cancers. The role of RAS/RAF pathway mutations i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3756867c0620d49e389bb6c5c29e26ca
https://doi.org/10.1200/jco.2008.18.8623

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