Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Jörg Standfuss"'
Autor:
Maximilian Wranik, Michal W. Kepa, Emma V. Beale, Daniel James, Quentin Bertrand, Tobias Weinert, Antonia Furrer, Hannah Glover, Dardan Gashi, Melissa Carrillo, Yasushi Kondo, Robin T. Stipp, Georgii Khusainov, Karol Nass, Dmitry Ozerov, Claudio Cirelli, Philip J. M. Johnson, Florian Dworkowski, John H. Beale, Scott Stubbs, Thierry Zamofing, Marco Schneider, Kristina Krauskopf, Li Gao, Oliver Thorn-Seshold, Christoph Bostedt, Camila Bacellar, Michel O. Steinmetz, Christopher Milne, Jörg Standfuss
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Serial crystallography at X-ray free-electron lasers (XFELs) permits the determination of radiation-damage free static as well as time-resolved protein structures at room temperature. Efficient sample delivery is a key factor for such experi
Externí odkaz:
https://doaj.org/article/f224092cc9184c46b2af0e3942817cf2
Autor:
Filip Leonarski, Jie Nan, Zdenek Matej, Quentin Bertrand, Antonia Furrer, Ishkhan Gorgisyan, Monika Bjelčić, Michal Kepa, Hannah Glover, Viktoria Hinger, Thomas Eriksson, Aleksander Cehovin, Mikel Eguiraun, Piero Gasparotto, Aldo Mozzanica, Tobias Weinert, Ana Gonzalez, Jörg Standfuss, Meitian Wang, Thomas Ursby, Florian Dworkowski
Publikováno v:
IUCrJ, Vol 10, Iss 6, Pp 729-737 (2023)
Serial and time-resolved macromolecular crystallography are on the rise. However, beam time at X-ray free-electron lasers is limited and most third-generation synchrotron-based macromolecular crystallography beamlines do not offer the necessary infra
Externí odkaz:
https://doaj.org/article/c27c457b830e451aab9a87a194dd5a8f
Autor:
Maximilian Wranik, Tobias Weinert, Chavdar Slavov, Tiziana Masini, Antonia Furrer, Natacha Gaillard, Dario Gioia, Marco Ferrarotti, Daniel James, Hannah Glover, Melissa Carrillo, Demet Kekilli, Robin Stipp, Petr Skopintsev, Steffen Brünle, Tobias Mühlethaler, John Beale, Dardan Gashi, Karol Nass, Dmitry Ozerov, Philip J. M. Johnson, Claudio Cirelli, Camila Bacellar, Markus Braun, Meitian Wang, Florian Dworkowski, Chris Milne, Andrea Cavalli, Josef Wachtveitl, Michel O. Steinmetz, Jörg Standfuss
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Photopharmacology manipulates the biological activity of small molecules by light. Using an X-ray laser, the authors follow the release of the drug azo-combretastatin A4 from tubulin and the concomitant structural changes over nine orders of magnitud
Externí odkaz:
https://doaj.org/article/31ccc9f5c1c7420b8b23b5fa45bdc9ee
Autor:
Michal. W. Kepa, Takashi Tomizaki, Yohei Sato, Dmitry Ozerov, Hiroshi Sekiguchi, Nobuhiro Yasuda, Koki Aoyama, Petr Skopintsev, Jörg Standfuss, Robert Cheng, Michael Hennig, Soichiro Tsujino
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Acoustic levitation has attracted attention in terms of chemical and biochemical analysis in combination with various analytical methods because of its unique container-less environment for samples that is not reliant on specific material ch
Externí odkaz:
https://doaj.org/article/e2bc12d9b2ec4ec88a5e6a104c810761
Autor:
Karol Nass, Camila Bacellar, Claudio Cirelli, Florian Dworkowski, Yaroslav Gevorkov, Daniel James, Philip J. M. Johnson, Demet Kekilli, Gregor Knopp, Isabelle Martiel, Dmitry Ozerov, Alexandra Tolstikova, Laura Vera, Tobias Weinert, Oleksandr Yefanov, Jörg Standfuss, Sven Reiche, Christopher J. Milne
Publikováno v:
IUCrJ, Vol 8, Iss 6, Pp 905-920 (2021)
Serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs) enables essentially radiation-damage-free macromolecular structure determination using microcrystals that are too small for synchrotron studies. However, SFX experiments o
Externí odkaz:
https://doaj.org/article/ad50bebd17b6464fb70fffcb3373aa32
Autor:
Karol Nass, Robert Cheng, Laura Vera, Aldo Mozzanica, Sophie Redford, Dmitry Ozerov, Shibom Basu, Daniel James, Gregor Knopp, Claudio Cirelli, Isabelle Martiel, Cecilia Casadei, Tobias Weinert, Przemyslaw Nogly, Petr Skopintsev, Ivan Usov, Filip Leonarski, Tian Geng, Mathieu Rappas, Andrew S. Doré, Robert Cooke, Shahrooz Nasrollahi Shirazi, Florian Dworkowski, May Sharpe, Natacha Olieric, Camila Bacellar, Rok Bohinc, Michel O. Steinmetz, Gebhard Schertler, Rafael Abela, Luc Patthey, Bernd Schmitt, Michael Hennig, Jörg Standfuss, Meitian Wang, Christopher J. Milne
Publikováno v:
IUCrJ, Vol 7, Iss 6, Pp 965-975 (2020)
Long-wavelength pulses from the Swiss X-ray free-electron laser (XFEL) have been used for de novo protein structure determination by native single-wavelength anomalous diffraction (native-SAD) phasing of serial femtosecond crystallography (SFX) data.
Externí odkaz:
https://doaj.org/article/ad7aad98478142d29b1d85fde6face15
Autor:
Daniel Mayer, Fred F. Damberger, Mamidi Samarasimhareddy, Miki Feldmueller, Ziva Vuckovic, Tilman Flock, Brian Bauer, Eshita Mutt, Franziska Zosel, Frédéric H. T. Allain, Jörg Standfuss, Gebhard F. X. Schertler, Xavier Deupi, Martha E. Sommer, Mattan Hurevich, Assaf Friedler, Dmitry B. Veprintsev
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The cellular functions of arrestins are determined in part by the pattern of phosphorylation on the G protein-coupled receptors (GPCRs) to which arrestins bind. Here, authors use a library of synthetic phosphopeptide analogues of the GPCR rhodopsin C
Externí odkaz:
https://doaj.org/article/3fb017c511b74ac5b642a4f342d8976b
Autor:
Michal. W. Kepa, Takashi Tomizaki, Yohei Sato, Dmitry Ozerov, Hiroshi Sekiguchi, Nobuhiro Yasuda, Koki Aoyama, Petr Skopintsev, Jörg Standfuss, Robert Cheng, Michael Hennig, Soichiro Tsujino
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/28e131e7ebc64b3f9ba380346127a8a9
Autor:
Tobias Weinert, Natacha Olieric, Robert Cheng, Steffen Brünle, Daniel James, Dmitry Ozerov, Dardan Gashi, Laura Vera, May Marsh, Kathrin Jaeger, Florian Dworkowski, Ezequiel Panepucci, Shibom Basu, Petr Skopintsev, Andrew S. Doré, Tian Geng, Robert M. Cooke, Mengning Liang, Andrea E. Prota, Valerie Panneels, Przemyslaw Nogly, Ulrich Ermler, Gebhard Schertler, Michael Hennig, Michel O. Steinmetz, Meitian Wang, Jörg Standfuss
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Serial crystallography was developed for protein crystal data collection with X-ray free-electron lasers. Here the authors present several examples which show that serial crystallography using high-viscosity injectors can also be routinely employed f
Externí odkaz:
https://doaj.org/article/03611f85d66b40d78ee218591843f7af
Autor:
Przemyslaw Nogly, Valerie Panneels, Garrett Nelson, Cornelius Gati, Tetsunari Kimura, Christopher Milne, Despina Milathianaki, Minoru Kubo, Wenting Wu, Chelsie Conrad, Jesse Coe, Richard Bean, Yun Zhao, Petra Båth, Robert Dods, Rajiv Harimoorthy, Kenneth R. Beyerlein, Jan Rheinberger, Daniel James, Daniel DePonte, Chufeng Li, Leonardo Sala, Garth J. Williams, Mark S. Hunter, Jason E. Koglin, Peter Berntsen, Eriko Nango, So Iwata, Henry N. Chapman, Petra Fromme, Matthias Frank, Rafael Abela, Sébastien Boutet, Anton Barty, Thomas A. White, Uwe Weierstall, John Spence, Richard Neutze, Gebhard Schertler, Jörg Standfuss
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Serial femtosecond crystallography using X-ray free-electron lasers has huge potential for time-resolved structural experiments. Here, the authors present a structure of the light-driven proton pump bacteriorhodopsin using these techniques.
Externí odkaz:
https://doaj.org/article/66e1d90ec93842009e8a6e6a5fac12b3