Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jörg Schlotterbeck"'
Autor:
Simon R. Roth, Bernhard Drotleff, Michael Lämmerhofer, Kerstin Henkel, Carlos Calderón, Jörg Schlotterbeck, Merja A. Neukamm
Publikováno v:
Analytical and Bioanalytical Chemistry
Dental plaque is a structurally organized biofilm which consists of diverse microbial colonies and extracellular matrix. Its composition may change when pathogenic microorganisms become dominating. Therefore, dental biofilm or plaque has been frequen
Autor:
Malgorzata Cebo, Michael Lämmerhofer, Jörg Schlotterbeck, Madhumita Chatterjee, Meinrad Gawaz
Publikováno v:
Analytica Chimica Acta. 1094:57-69
In this study, a combined targeted/untargeted UHPLC-ESI-QTOF-MS/MS method for the targeted quantitative analysis of the primary platelet lipid mediators thromboxane B2 (TXB2), 12S-hydroxy-5Z,8E,10E-heptadecatrienoic acid (HHT) and its oxidation produ
Publikováno v:
Analytica Chimica Acta. 1048:66-74
In this study, two monophasic isopropanol-water mixtures (IPA:H2O 75:25 v/v and IPA:H2O 90:10 v/v) were compared with traditionally employed biphasic methods of Bligh & Dyer and Matyash et al. as extraction systems for lipidomics analysis in Hela cel
Publikováno v:
Analytica Chimica Acta. 1046:1-15
A non-targeted lipidomics workflow based on C8 core-shell particle ultra high-performance liquid chromatography (UHPLC) hyphenated to ESI-QTOF-MS in data-independent acquisition (DIA) mode with sequential window acquisition of all theoretical fragmen
Autor:
Malgorzata Cebo, Madhumita Chatterjee, Meinrad Gawaz, Carlos Calderón Castro, Jörg Schlotterbeck, Michael Lämmerhofer
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 205
Lipids play a major role in platelet signaling and activation. In this study, we analyzed the platelet lipidome in an untargeted manner by reversed-phase UHPLC for lipid species separation coupled to high-resolution QTOF-MS/MS in data-independent acq
Publikováno v:
Journal of Separation Science. 41:4286-4295
Undaria pinnatifida (Wakame) alga contains high amounts of hexadeca-4Z,7Z,10Z,13Z-tetraenoic acid which was reported to decrease the efficiency of cisplatin chemotherapeutics. To obtain a fatty acid enriched extract of this ω-3 poly-unsaturated fatt
Publikováno v:
Analytica chimica acta. 1086
Lipidomics has gained rising attention in recent years. Several strategies for lipidomic profiling have been developed, with targeted analysis of selected lipid species, typically utilized for lipid quantification by low-resolution triple quadrupole
Publikováno v:
Analytical and bioanalytical chemistry. 411(2)
Polyunsaturated fatty acids are important signaling molecules. A recent study reported hexadeca-4Z,7Z,10Z,13Z-tetraenoic acid, 12-oxo-5Z,8E,10E-heptadecatrienoic acid, and (12S)-hydroxy-5Z,8E,10E-heptadecatrienoic acid as chemotherapy resistance-indu
Autor:
Meinrad Gawaz, Tilman E. Schäffer, Tobias Geisler, Monika Zdanyte, Nada Alnaggar, Jörg Schlotterbeck, Madhumita Chatterjee, Dominik Rath, Michael Lämmerhofer, Johannes Rheinlaender, Oliver Borst, Britta Walker-Allgaier, Iris Müller
Publikováno v:
European heart journal. 38(25)
Aims Hyperlipidaemia enhances susceptibility to thrombosis, while platelet oxidixed LDL (oxLDL) binding in acute coronary syndrome (ACS) correlates with activation status. This study explores the platelet lipidome in symptomatic coronary artery disea