Výsledky vyhledávání - "Jörg Lauber"

The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation

Autor: Holger Heine, Christoph Lange, Jörg Lauber, Jan Buer, Torsten Goldmann, Antje Blumenthal, Norbert Reiling, Stefan Ehlers, Ernst Brandt

Publikováno v: Blood. 108:965-973

Microarray - assisted gene - expression screens of human macrophages revealed WNT5A, a homolog of Wingless, a key regulator of Drosophila melanogaster embryonic segmentation and patterning, to be consistently up-regulated following stimulation with d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fca01d43030a6241f90026668977358
https://doi.org/10.1182/blood-2005-12-5046

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Gene expression patterns of epithelial cells modulated by pathogenicity factors ofYersinia enterocolitica

Autor: Robert Geffers, Juliane Krejci, N. Speer, Ingo B. Autenrieth, Erwin Bohn, Steffen Müller, Christian Spieth, Andreas Zell, Jörg Lauber, Jan Buer, Birgit Manncke

Publikováno v: Cellular Microbiology. 6:129-141

Summary Epithelial cells express genes whose products signal the presence of pathogenic microorganisms to the immune system. Pathogenicity factors of enteric bacteria modulate host cell gene expression. Using microarray technology we have profiled ep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa97fd568a5d8cbb8b15585e1e349724
https://doi.org/10.1046/j.1462-5822.2003.00346.x

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Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells

Autor: Michael P. Manns, Torsten Wüstefeld, Ande Satyanarayana, Stefanie U. Wiemann, Maria A. Blasco, Jörg Lauber, Jan Buer, K.L. Rudolph, Kurt E.J. Dittmar

Publikováno v: The EMBO Journal. 22:4003-4013

Telomere shortening limits the regenerative capacity of primary cells in vitro by inducing cellular senescence characterized by a permanent growth arrest of cells with critically short telomeres. To test whether this in vitro model of cellular senesc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529709f81d5062bff9cf28a38832d37d
https://doi.org/10.1093/emboj/cdg367

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G-CSF as immune regulator in T cells expressing the G-CSF receptor: implications for transplantation and autoimmune diseases

Autor: Bernd Hertenstein, Anke Franzke, Wiebke Hansen, Patricia Gatzlaff, Arnold Ganser, Christian Könecke, Jörg Lauber, Jan Buer, Wenji Piao, Angela Schmitt-Thomsen

Publikováno v: Blood. 102:734-739

Results from experimental models, in vitro studies, and clinical data indicate that granulocyte colony-stimulating factor (G-CSF) stimulation alters T-cell function and induces Th2 immune responses. The immune modulatory effect of G-CSF on T cells re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63af2b848fcb5e530cc9fccf882b94ae
https://doi.org/10.1182/blood-2002-04-1200

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Fingerprints of anergic T cells

Autor: Oskar Lechner, Jörg Lauber, Harald von Boehmer, Anke Franzke, Adelaida Sarukhan, Jan Buer

Publikováno v: Current Biology. 11:587-595

Peripheral T cell tolerance may result from activation-induced cell death [1], anergy [1], and/or immune response modulation by regulatory T cells [2] . In mice that express a transgenic receptor specific for peptide 111–119 of influenza hemaggluti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f010885636d2860f1ca6ea610c1e107
https://doi.org/10.1016/s0960-9822(01)00160-9

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Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T½)

Autor: Andrea Hoffmann, Nicole Betat, Gerhard Gross, Marion Ahrens, Dietmar Bächner, Jörg Lauber, Dietmar Schröder, Leopold Flohé, Peter Steinert

Publikováno v: Developmental Dynamics. 213:398-411

ABmp-dependent in vitro model was used to identify cDNAs during the manifestation of mesenchymal lineages. This model involves the recombinant expression of Bmps (Bmp-2, Bmp-4-7) in murine mesenchymal C3H10T1/2 progenitors, which leads to the differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8dd3dd15c6f130b9374e38a84862df1a
https://doi.org/10.1002/(sici)1097-0177(199812)213:4<398::aid-aja5>3.0.co

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Constitutive secretion of β-trace protein by cultivated porcine choroid plexus epithelial cells: Elucidation of its complete amino acid and cDNA sequences

Autor: Hans-Joachim Galla, Sabine Hellwig, Jörg Lauber, Gerhard Gross, Harald S. Conradt, Ulla Gath, Andrea Hoffmann, Rita Getzlaff

Publikováno v: Journal of Cellular Physiology. 169:235-241

Primary porcine choroid plexus epithelial cells cultivated in chemically defined medium maintain their epithelial characteristics and form confluent monolayers. They produce a fluid the composition of which resembles cerebrospinal fluid. The present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ab90756e22ae0b1c71c25ed82588cbd
https://doi.org/10.1002/(sici)1097-4652(199611)169:2<235::aid-jcp2>3.0.co

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Developmental expression of murine β-trace in embryos and adult animals suggests a function in maturation and maintenance of blood-tissue barriers

Autor: Jörg Lauber, Dietmar Bächner, Andrea Hoffmann, Gerhard Gross, Nicole Betat

Publikováno v: Developmental Dynamics. 207:332-343

The complete cDNA for murine Beta-trace protein was isolated by RT-PCR using degenerate primers designed according to amino acid sequences derived from tryptic peptides. It encodes a protein of 165 amino acids (calculated molecular weight 18,472 Da)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6bec2336e6a8a04bcb0470512d6306aa
https://doi.org/10.1002/(sici)1097-0177(199611)207:3<332::aid-aja10>3.0.co

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Ongoing Coxsackievirus Myocarditis Is Associated with Increased Formation and Activity of Myocardial Immunoproteasomes

Autor: Antje Voigt, Silke Meiners, Reinhard Kandolf, N. Speer, Martina Sauter, Jörg Lauber, Ulrike Kuckelkorn, Gudrun Szalay, Karl Stangl, Andreas Zell, Christian Spieth, Karin Klingel

A growing body of evidence indicates that viral infections of the heart contribute to ongoing myocarditis and dilated cardiomyopathy. Murine models of coxsackievirus B3 (CVB3)-induced myocarditis mimic the human disease and allow identification of su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d3ae715880de0885320b4c13f53b4c
https://europepmc.org/articles/PMC1606581/

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