Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jörg Klufa"'
Publikováno v:
Life, Vol 11, Iss 11, p 1237 (2021)
The skin is the outermost barrier protecting the body from pathogenic invasion and environmental insults. Its breakdown initiates the start of skin inflammation. The epidermal growth factor (EGFR) on keratinocytes protects this barrier, and its dysfu
Externí odkaz:
https://doaj.org/article/f53435f55ffb48c2af4e18f36b8ad734
Autor:
Peter Arne Gerber, Petra Boukamp, Anne Schorr, Erich Bünemann, Anja Müller-Homey, Peter Hevezi, Stephan Alexander Braun, Frauke Alves, Bernhard Homey, Stephan Seeliger, Andreas Kislat, Péter Oláh, Stephanie Holtz, Albert Zlotnik, Andreas Hippe, Maria Sibilia, Bettina Alexandra Buhren, Sergio A. Lira, Andor Pivarcsi, Jörg Klufa, Thomas K. Hoffmann, Nikolas H. Stoecklein, Jens W. Fischer, Holger Schrumpf, Jonathan P. Sleeman, Martin Steinhoff, Katharina Jannasch, Nicole Amberg, Thomas Bauer
Publikováno v:
British Journal of Cancer
British journal of cancer, 125 (9), 1318
British journal of cancer, 125 (9), 1318
The activation of the EGFR/Ras-signalling pathway in tumour cells induces a distinct chemokine repertoire, which in turn modulates the tumour microenvironment.The effects of EGFR/Ras on the expression and translation of CCL20 were analysed in a large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002204320db60b3bd69f13d50b60c924
Autor:
Daniel Schulz, Jörg Klufa, Igor Vujic, Beate M. Lichtenberger, Hana Kozakova, Maria Sibilia, Buck Hanson, Klemens Rappersberger, Craig W. Herbold, Thomas Mohr, Bernd Bodenmiller, Philipp Starkl, Dagmar Srutkova, Alexander Loy, Sylvia Knapp, Thomas Bauer
Publikováno v:
Science Translational Medicine
Epidermal growth factor receptor (EGFR)-targeted anticancer therapy induces stigmatizing skin toxicities affecting patients' quality of life and therapy adherence. The lack of mechanistic details underlying these adverse events hampers their manageme