Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jörg Klingelhöfer"'
Autor:
Jörg Klingelhöfer, Birgitte Grum-Schwensen, Mette K. Beck, Rikke Stagaard Petersen Knudsen, Mariam Grigorian, Eugene Lukanidin, Noona Ambartsumian
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 12, Pp 1260-1268 (2012)
The small Ca-binding protein, S100A4, has a well-established metastasis-promoting activity. Moreover, its expression is tightly correlated with poor prognosis in patients with numerous types of cancer. Mechanistically, the extracellular S100A4 drives
Externí odkaz:
https://doaj.org/article/89e965c037fd4b04bd81f4348b52da21
Autor:
Birgitte Forst, Matilde Thye Hansen, Jörg Klingelhöfer, Henrik Devitt Møller, Gitte Helle Nielsen, Birgitte Grum-Schwensen, Noona Ambartsumian, Eugene Lukanidin, Mariam Grigorian
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10374 (2010)
The tumor microenvironment has been described as a critical milieu determining tumor growth and metastases. A pivotal role of metastasis-inducing S100A4 in the development of tumor stroma has been proven in animal models and verified in human breast
Externí odkaz:
https://doaj.org/article/02f28f10082240f2b4a2ffd64e28d43f
Autor:
Noona Ambartsumian, Eugene Lukanidin, Jonathan Sleeman, Per Guldberg, Mariam Grigorian, Hiromi Yanagisawa, Jörg Klingelhöfer, Rune Troelsgaard Pedersen, Mika Frankel, Natascha Cremers, Ulrik Ralfkjær, Henrik Devitt Møller
Supplementary Figures S1-S4; Supplementary Materials and Methods; Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946bf642dd39f813250ed79423152ba7
https://doi.org/10.1158/1541-7786.22518657.v1
https://doi.org/10.1158/1541-7786.22518657.v1
Autor:
Mohammad Saleem, Badrinath R. Konety, Christopher A. Warlick, Noona Ambartsumian, Jinhua Wang, Jörg Klingelhöfer, Paari Murugan, Marina G. Ferrari, Ashraf Shabaneh, Hifzur R. Siddique, Arpit Rao, Tabish Hussain, Adrian P. Mansini, Arsheed A. Ganaie
(Ai) Box-plot shows the association of copy number of S100A4 gene to Gleason Score of prostate tumors in CaP patients. The graph was generated from the analysis of TCGA clinical data using Oncomine platform. (Aii) Image shows the detection of S100A4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e935a4c1fe1fc23736beff519d270f0
https://doi.org/10.1158/1535-7163.22519167
https://doi.org/10.1158/1535-7163.22519167
Autor:
Noona Ambartsumian, Eugene Lukanidin, Jonathan Sleeman, Per Guldberg, Mariam Grigorian, Hiromi Yanagisawa, Jörg Klingelhöfer, Rune Troelsgaard Pedersen, Mika Frankel, Natascha Cremers, Ulrik Ralfkjær, Henrik Devitt Møller
The tumor microenvironment is now recognized as a major factor in determining the survival and growth of disseminated tumor cells at potential metastatic sites. Tumor cells send signals to stroma cells and stimulate them to produce factors that in tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e2323b93c721e703aa5809d42fe309
https://doi.org/10.1158/1541-7786.c.6542052.v1
https://doi.org/10.1158/1541-7786.c.6542052.v1
Autor:
Noona Ambartsumian, Eugene Lukanidin, Boye Schnack Nielsen, Kasper Almholt, Mariam Grigorian, Jörg Klingelhöfer, Birgitte Grum-Schwensen
Supplementary Materials, Table 1-2, Figure 1 from Lung Metastasis Fails in MMTV-PyMT Oncomice Lacking S100A4 Due to a T-Cell Deficiency in Primary Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559947254249763abe9fd0dfd2834b33
https://doi.org/10.1158/0008-5472.22386908
https://doi.org/10.1158/0008-5472.22386908
Autor:
Hifzur R. Siddique, Mohammad Saleem, Jörg Klingelhöfer, Jinhua Wang, Christopher A. Warlick, Adrian P. Mansini, Paari Murugan, Ashraf Shabaneh, Badrinath R. Konety, Arpit Rao, Arsheed A. Ganaie, Tabish Hussain, Noona Ambartsumian, Marina G. Ferrari
Publikováno v:
Molecular Cancer Therapeutics. 19:2598-2611
S100A4 oncoprotein plays a critical role during prostate cancer progression and induces immunosuppression in host tissues. We hypothesized that S100A4-regulated oncogenic activity in immunosuppressed prostate tumors promotes growth of neoplastic cell
Autor:
Kathrine Lundø, K.K. Rasmussen, Jan Hoeber, Anders Christiansen, David P.D. Woldbye, Elena N. Kozlova, Henrik Hertz, Amaia de Diego Ajenjo, Jörg Klingelhöfer, Alexander L. Nielsen, Stanislava Pankratova, Oksana Dmytriyeva
Publikováno v:
ACS Chemical Neuroscience. 11:1270-1282
Vascular endothelial growth factor B (VEGFB) is a pleiotropic trophic factor, which in contrast to the closely related VEGFA is known to have a limited effect on angiogenesis. VEGFB improves survival in various tissues including the nervous system, w
Autor:
Arsheed A, Ganaie, Adrian P, Mansini, Tabish, Hussain, Arpit, Rao, Hifzur R, Siddique, Ashraf, Shabaneh, Marina G, Ferrari, Paari, Murugan, Jörg, Klingelhöfer, Jinhua, Wang, Noona, Ambartsumian, Christopher A, Warlick, Badrinath R, Konety, Mohammad, Saleem
Publikováno v:
Molecular cancer therapeutics. 19(12)
S100A4 oncoprotein plays a critical role during prostate cancer progression and induces immunosuppression in host tissues. We hypothesized that S100A4-regulated oncogenic activity in immunosuppressed prostate tumors promotes growth of neoplastic cell
Autor:
Chiraz Chaabane, Antonija Sakic, Brenda R. Kwak, Mariam Grigorian, Sylvain Lemeille, Noona Ambartsumian, Marie-Luce Bochaton-Piallat, Jörg Klingelhöfer
Publikováno v:
Sakic, A, Chaabane, C, Ambartsumian, N, Klingelhofer, J, Lemeille, S, Kwak, B R, Grigorian, M & Bochaton-Piallat, M-L 2022, ' Neutralization of S100A4 induces stabilization of atherosclerotic plaques : role of smooth muscle cells ', Cardiovascular Research, vol. 118, no. 1, pp. 141-155 . https://doi.org/10.1093/cvr/cvaa311
Cardiovascular Research, Vol. 118, No 1 (2022) pp. 141-155
Cardiovascular Research
Cardiovascular Research, Vol. 118, No 1 (2022) pp. 141-155
Cardiovascular Research
Aims During atherosclerosis, smooth muscle cells (SMCs) accumulate in the intima where they switch from a contractile to a synthetic phenotype. From porcine coronary artery, we isolated spindle-shaped (S) SMCs exhibiting features of the contractile p