Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Jörg Hagmann"'
Autor:
Jasmin Fertey, Jörg Hagmann, Hans‐Joachim Ruscheweyh, Christian Munk, Susanne Kjaer, Daniel Huson, Juliane Haedicke‐Jarboui, Frank Stubenrauch, Thomas Iftner
Publikováno v:
Cancer Medicine, Vol 9, Iss 3, Pp 1058-1068 (2020)
Abstract Several studies have demonstrated that the viral genome can be methylated by the host cell during progression from persistent infection to cervical cancer. The aim of this study was to investigate whether methylation at a specific site could
Externí odkaz:
https://doaj.org/article/6f62c698defa435bb9517ce21dbf8b2f
Autor:
Patrick Hüther, Jörg Hagmann, Adam Nunn, Ioanna Kakoulidou, Rahul Pisupati, David Langenberger, Detlef Weigel, Frank Johannes, Sebastian J. Schultheiss, Claude Becker
Publikováno v:
Quantitative Plant Biology, Vol 3 (2022)
Whole-genome bisulfite sequencing (WGBS) is the standard method for profiling DNA methylation at single-nucleotide resolution. Different tools have been developed to extract differentially methylated regions (DMRs), often built upon assumptions from
Externí odkaz:
https://doaj.org/article/2959635d3c8b4446b5ae0f1218a6fb26
Autor:
Cristina A Barragan, Rui Wu, Sang-Tae Kim, Wanyan Xi, Anette Habring, Jörg Hagmann, Anna-Lena Van de Weyer, Maricris Zaidem, William Wing Ho Ho, George Wang, Ilja Bezrukov, Detlef Weigel, Eunyoung Chae
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008313 (2019)
In many plant species, conflicts between divergent elements of the immune system, especially nucleotide-binding oligomerization domain-like receptors (NLR), can lead to hybrid necrosis. Here, we report deleterious allele-specific interactions between
Externí odkaz:
https://doaj.org/article/3dfeea69a47a4665a108f55aa9dc69d6
Autor:
Daniel Koenig, Jörg Hagmann, Rachel Li, Felix Bemm, Tanja Slotte, Barbara Neuffer, Stephen I Wright, Detlef Weigel
Publikováno v:
eLife, Vol 8 (2019)
Genetic drift is expected to remove polymorphism from populations over long periods of time, with the rate of polymorphism loss being accelerated when species experience strong reductions in population size. Adaptive forces that maintain genetic vari
Externí odkaz:
https://doaj.org/article/4527ed8efc5f4d48848588abec805c19
Autor:
Anjar Wibowo, Claude Becker, Gianpiero Marconi, Julius Durr, Jonathan Price, Jörg Hagmann, Ranjith Papareddy, Hadi Putra, Jorge Kageyama, Jorg Becker, Detlef Weigel, Jose Gutierrez-Marcos
Publikováno v:
eLife, Vol 7 (2018)
Externí odkaz:
https://doaj.org/article/fcc1fb40594940c4ac548c93e742c0a1
Autor:
Laura Pisarsky, Ruben Bill, Ernesta Fagiani, Sarah Dimeloe, Ryan William Goosen, Jörg Hagmann, Christoph Hess, Gerhard Christofori
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1161-1174 (2016)
Despite the approval of several anti-angiogenic therapies, clinical results remain unsatisfactory, and transient benefits are followed by rapid tumor recurrence. Here, we demonstrate potent anti-angiogenic efficacy of the multi-kinase inhibitors nint
Externí odkaz:
https://doaj.org/article/2e1f3cdad32948ae82dae8837ddcdd50
Autor:
Moises Exposito-Alonso, Claude Becker, Verena J Schuenemann, Ella Reiter, Claudia Setzer, Radka Slovak, Benjamin Brachi, Jörg Hagmann, Dominik G Grimm, Jiahui Chen, Wolfgang Busch, Joy Bergelson, Rob W Ness, Johannes Krause, Hernán A Burbano, Detlef Weigel
Publikováno v:
PLoS Genetics, Vol 14, Iss 2, p e1007155 (2018)
By following the evolution of populations that are initially genetically homogeneous, much can be learned about core biological principles. For example, it allows for detailed studies of the rate of emergence of de novo mutations and their change in
Externí odkaz:
https://doaj.org/article/8b7a5737e41847aca48b2ee9652e2fa0
Autor:
Ulrich Lutz, David Posé, Matthias Pfeifer, Heidrun Gundlach, Jörg Hagmann, Congmao Wang, Detlef Weigel, Klaus F X Mayer, Markus Schmid, Claus Schwechheimer
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005588 (2015)
Plants integrate seasonal cues such as temperature and day length to optimally adjust their flowering time to the environment. Compared to the control of flowering before and after winter by the vernalization and day length pathways, mechanisms that
Externí odkaz:
https://doaj.org/article/66fb26ac099f4d6881db8a2d713bbb6c
Autor:
Jörg Hagmann, Claude Becker, Jonas Müller, Oliver Stegle, Rhonda C Meyer, George Wang, Korbinian Schneeberger, Joffrey Fitz, Thomas Altmann, Joy Bergelson, Karsten Borgwardt, Detlef Weigel
Publikováno v:
PLoS Genetics, Vol 11, Iss 1, p e1004920 (2015)
There has been much excitement about the possibility that exposure to specific environments can induce an ecological memory in the form of whole-sale, genome-wide epigenetic changes that are maintained over many generations. In the model plant Arabid
Externí odkaz:
https://doaj.org/article/e2f5de4af2b24cb89901576276926984
Publikováno v:
PLoS Genetics, Vol 10, Iss 11, p e1004785 (2014)
DNA methylation is an ancient molecular modification found in most eukaryotes. In plants, DNA methylation is not only critical for transcriptionally silencing transposons, but can also affect phenotype by altering expression of protein coding genes.
Externí odkaz:
https://doaj.org/article/d04c096f7e7e4259b5aeef1663de7f74